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Introduction Delayed palliative management (DPM) is an alternative for prostate cancer (PCa) patients with poor performance status, or those who received radical treatment but progressed and no longer meet the criteria for curative treatment. PIONEER is a large network of federated data analytic platforms in PCa that aims to improve its care through the application of big data analytics. The objec

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Background: People with aphasia (PWA) after ischemic stroke often have difficulties in communication and social participation. To individualise rehabilitation and optimise recovery, there is a need for knowledge regarding prevalence of aphasia, and language functions in relation to long-term recovery and health-related quality of life (HRQoL). In this study, we examined these issues in a Swedish s

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PURPOSE: The Obesity and Disease Development Sweden (ODDS) study was designed to create a large cohort to study body mass index (BMI), waist circumference (WC) and changes in weight and WC, in relation to morbidity and mortality.PARTICIPANTS: ODDS includes 4 295 859 individuals, 2 165 048 men and 2 130 811 women, in Swedish cohorts and national registers with information on weight assessed once (2

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BACKGROUND: In patients with chronic coronary syndrome undergoing percutaneous coronary intervention, the optimal timing of P2Y12 inhibitors' administration is uncertain. We compared pretreatment versus treatment in the catheterization laboratory (In-Cathlab) in a real-world population. METHODS: In Swedish Coronary Angiography and Angioplasty Registry, all patients with chronic coronary syndrome u

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Background: [18F]PSMA-1007 is a promising tracer for integrated positron emission tomography and computed tomography (PET/CT). Objective: Our aim was to assess the diagnostic accuracy of [18F]PSMA-1007 PET/CT for primary staging of lymph node metastasis before robotic-assisted laparoscopy (RALP) with extended lymph node dissection (ePLND). Design, Setting and Participants: The study was a retrospe

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Do virtual representations, intended for teaching and learning, afford different constraints and affordances compared to their physical twins, and may this lead to different ways of interaction and understanding? In this line of inquiry, and with the perspective on learning as an extended activity, where learning can be mediated through the interaction with artefacts, the present study has transla

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Child stunting (chronic undernutrition) is a major public health concern in low- and middle-income countries. In Rwanda, an estimated 33% of children are affected. This study investigated the household living conditions and the impact of gender-related decision-making on child stunting. The findings contribute to ongoing discussion on this critical public health issue. In December 2021, a populati

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Background: Specific medical guidelines for health surveillance exist for people with Down syndrome (DS) since 25 years but knowledge of adherence to the guidelines is lacking. The guidelines were developed to avoid unnecessary suffering from preventable conditions. The aims of the study were to investigate 1) planned health care visits in relation to the co-morbidities described in specific medic

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Objective: To assess foetal circulating free foetal haemoglobin (fHbF) levels and heme defences, correlated to foetal circulatory biometry and foetal sex in severe early-onset foetal growth restriction (FGR). Design, Setting and Population: A prospective study severe early-onset foetal growth restriction pregnancies with close clinical management (estimated foetal weight (EFW) < 3rd centile and <

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Previously proposed high spin states in Na22,23 are compared with calculations from the cranked Nilsson model including Strutinsky renormalization. High K rotational isomers are proposed for Iπ=6- in Na22 and 11/2+, 13/2+, and possibly 15/2+ in Na23. The positive parity yrast sequences in these two nuclei are analyzed in terms of the change from collective to single particle behavior at I=9 (22Na)

June visits and summer greetings!

June visits and summer greetings! June visits and summer greetings! Published 20 June 2024 Summer is approaching (or is already here), and the lab has had an intense spring that culminated in many prominent visits in June! We've had so many exciting questions and discussions with everyone, and we feel proud and happy to have such a fantastic operation to showcase and share with others. Here are so

https://www.humlab.lu.se/article/june-visits-and-summer-greetings/ - 2026-07-17

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När är en bild barnpornografisk? Frågan kan utredas rättsdogmatiskt, men också empiriskt genom att domstolarnas prövningar av misstänkt barnpornografiska bilder undersöks. Det är inte självklart att de olika utredningsmetoderna ger samstämmiga svar; domare dömer inte nödvändigtvis på ett sätt som överensstämmer med gällande rätt. I den här undersökningen jämfördes innebörden av barnpornografi enliWhen does an image constitute child pornography? The issue can be investigated with a legal dogmatic method, but also with an empirically method and by examining the courts' trials regarding suspected child pornographic material. It is not obvious that the different methods of investigation provide consistent answers; judges do not necessarily decide in a manner consistent with applicable law.

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Den svenska missbruks- och narkotikamodellen bygger på en restriktiv straffrättslig kontroll med ett narkotikafritt samhälle som mål. Trots detta har Sverige idag högst narkotikarelaterad dödlighet i Europa. Portugal använder istället en modell där skademinimering är centralt och förvärv och innehav avsett för eget bruk samt eget bruk är avkriminaliserat. I dagsläget verkar också Norge ta in på etThe Swedish drug control strategy is based on restrictive criminal law where the goal is a society free from illicit drugs. However, today Sweden has the highest drug-related mortality in Europe. Countries like Portugal use a different model where harm reduction is central and acquisitions, personal possession and consumption are decriminalized. Norway is also taking an interest in switching to a

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Transformativt ledarskap är en av de mest inflytelserika teorierna inom ledarskapsforskning idag och dess fördelar har blivit uppmärksammade från flertalet perspektiv. Syftet med följande studie var att undersöka relationen mellan personlighetsdrag i HEXACO-modellen, en utmanare till den etablerade femfaktormodellen, och uppskattandet av transformativ ledarskapsstil. Datan samlades in genom en intTransformational leadership is one of the most influential theories in leadership research today and its benefits have been highlighted from several perspectives. The purpose of the following study was to examine the relationship between personality traits in the HEXACO model, a contender to the established five-factor model, and the appreciation of transformational leadership style. The data was

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Trots att exponering- och responsprevention (ERP) är en effektiv behandling för patienter med tvångssyndrom (eng: obsessive-compulsive disorder; OCD), blir inte alla hjälpta. Medan många författare har intresserat sig för demografiska och kliniska faktorers betydelse för behandlingsutfall, är det få studier som har undersökt hur processer som uppstår under behandling (t.ex. förändring i motivationExposure and response prevention (ERP) is an effective treatment for obsessive-compulsive disorder (OCD), but not everyone benefits. While many authors have explored the contribution of demographic and clinical factors in relation to treatment outcome, few studies have investigated how processes that occur during the course of treatment (e.g., changes in motivation) relate to treatment outcome. Th

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Ansträngningsutlöst andningsfunktionsstörning drabbar främst barn och ungdomar, oftast i samband med idrottsutövning och är vanligare bland flickor än pojkar. Mekanismerna bakom besvären är komplexa och inte helt klarlagda. Enhetliga rutiner för omhändertagandet finns inte. Syftet med uppsatsen var att kartlägga och utvärdera omhändertagandet av personer med dessa besvär vid Röst- och TalvårdsavdeExercise-induced respiratory dysfunction affects mostly children and young people, usually during athletic performance, and is more common among girls than boys. The mechanisms of the disorder are complex and not fully understood. Uniform clinical procedures for examination and treatment of these patients are not established. The purpose of this paper was to identify and evaluate the present care