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Coagulation Systems of Invertebrates and Vertebrates and Their Roles in Innate Immunity: The Same Side of Two Coins?

Bacterial infections represent a serious health care problem, and all multicellular organisms have developed defense mechanisms to eliminate pathogens that enter the host via different paths including wounds. Many invertebrates have an open circulatory system, and effective coagulation systems are in place to ensure fast and efficient closure of wounds. It was proposed early on that coagulation sy

Indistinguishable genomic profiles and shared prognostic markers in undifferentiated pleomorphic sarcoma and leiomyosarcoma: different sides of a single coin?

Soft tissue sarcoma (STS) diagnostics and prognostics are challenging, particularly in highly malignant and pleomorphic subtypes such as undifferentiated pleomorphic sarcoma (UPS) and leiomyosarcoma (LMS). We applied 32K BAC arrays and gene expression profiling to 18 extremity soft tissue LMS and 31 extremity soft tissue UPS with the aim of identifying molecular subtype signatures and genomic prog

Aggressive pituitary tumours and carcinomas : two sides of the same coin?

The European Society of Endocrinology (ESE) survey reported on the largest cohort of 125 aggressive pituitary tumours (APT) and 40 pituitary carcinomas (PC). Whilst the survey focused on treatment effectiveness, all pathological data were not explored in detail. Here, we comment on some interesting pathological findings, notably the difference between APT and PC.

The Other Side of the Coins : The Environmental Impact of Greenfield FDI in Sub-Saharan Africa´s Pollution-Intensive Industries and the Role of Governance

While foreign direct investments (FDI) are promoted as a vehicle for economic development their environmental consequences are less estab-lished. This study tests the hypotheses that 1) FDI led to environmental deg-radation in form of increased greenhouse gas emissions during Sub-Saharan Africa´s recent growth spurt but that 2) this impact was felt to a lesser extent in countries with a higher qua

Two sides of the same coin : The experiences of high-achieving women in the Swedish workplace

Adopting a qualitative approach to the investigation of high achievement, the authors analyzed how high-achieving women in the Swedish workplace made meaning of positive and negative experiences in their work. The data consisted of interviews with 15 women identified as being high achieving in their respective field, and it was analyzed using grounded theory methodology. The women described five d

Are aggressive pituitary tumors and carcinomas two sides of the same coin? Pathologists reply to clinician’s questions

Pituitary adenohypophyseal tumors are considered as benign and termed “adenomas”. However, many tumors are invasive and a proportion of these exhibit an “aggressive behavior” with premature death due to progressive growth. Only very rare (0.2%) tumors with metastases are considered malignant and termed “carcinomas”. Taking into account this variability in behavior and the oncological definition, p

Bet on both sides of the coin to improve the organizational climate: The impact of congruent task and role clarity between leaders and staff

Four organizations at Stockholm-Arlanda airport are going through various organizational changes. They are preparing for present and future demands through structural changes, implementation of new technology, training, and other efficiency and capacity improving measures. The change processes will be followed during two years of which this paper presents the baseline measurement. The key factors

Cancer and autoimmunity: two sides of the same coin. Complement system proteins in the regulation of immune responses.

Factor H is an inhibitor of the complement system, essential for controlling the alternative pathway and also playing a crucial role in various cellular functions. In this thesis, we identified new intriguing functions of FH as a survival factor for primary human monocytes, promoting their differentiation into immunosuppressive macrophages. We showed that FH is expressed by human breast cancer cel

The Pahlavis and the Other Side of the Coins

It was with great interest that I read “Political Power of Iranian Hierocracies” by János Jany published in Comparative Civilizations Review. Writing about Iranian history is not an easy task because historical points of view have been highly politicized. Such is particularly the case when discussing the Pahlavi dynasty, particularly its founder, Reza Shah Pahlavi, and his successor, Mohammed Reza

The two sides of the coin : joint project leader interaction in university-industry collaboration projects

This article focuses on how academic and industrial leaders view central aspects of the initiation, collaboration process, and the outcomes in government-funded R&D projects. In much previous work on university-industry collaborations (UICs), universities or researchers and/or firms have been studied without any direct reference to the other party, thus neglecting the fact that the motivations

Coins have both sides : Revealing the structure and pattern of global interdependence network for five critical metals

Evaluating the trade interdependence among countries is the key to understanding critical metal minerals security. By constructing a novel interdependence network, this paper reveals a more comprehensive world hierarchy and risk system of critical metals, and focuses on the interdependencies between China and the US-led MSP countries before and after the Sino-US trade disputes. The results indicat

Two sides of the same green coin? A legal analysis of the concept of the (green) industrial competitiveness of the Union through the Net-Zero Industry Act

I den pågående kampen mot klimathotet har Europeiska unionen antagit en ledande roll för att fullfölja skiftet mot en grön ekonomi, bland annat genom att fokusera på att stärka konkurrenskraften avseende tillverkningen av netto-noll energiindustrin och säkra de nödvändiga råvarorna för denna omställning. För att möjliggöra detta presenterade den Europeiska kommissionen i mars 2023, i samband med pIn the global race against climate change, the answer of the European Union is the transition towards a green economy by focusing on strengthening the competitiveness of the net-zero technology industry and securing the necessary critical materials. To do so, the Union presented two legislative acts in the European Green Deal Industrial Plan in 2023, amongst which the Net-Zero Industry Act. While