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Background: Germline BRCA1 mutations confer a substantial lifetime risk of breast and ovarian cancer, but whether cancer at other sites is increased is less clear. To evaluate the risks of other cancers in BRCA1 mutation carriers, we conducted a cohort study of 11 847 individuals from 699 families segregating a BRCA1 mutation that were ascertained in 30 centers across Europe and North America. Met

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Background Patients with chromosome 5 abnormalities and high-risk myelodysplastic syndromes or acute myeloid leukemia have a poor outcome. We hypothesized that increasing doses of lenalidomide may benefit this group of patients by inhibiting the tumor clone, as assessed by fluorescence in situ hybridization for del(5q31). Design and Methods Twenty-eight patients at diagnosis or with relapsed disea

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Objective: To examine whether the relationship between the metabolic syndrome (MetS) and various sleep parameters [sleep duration, symptoms of sleep-disordered breathing (SDB), and sleep disturbances] varies by age. Methods: Waist circumference, blood pressure, triglycerides, high-density lipoprotein cholesterol, and fasting glucose were used to determine MetS status in a cohort (N = 19,691) of mi

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Introduction: Despite spectacular progress in cellular transplantology, there are still many concerns about the fate of transplanted cells. More preclinical studies are needed, especially on large animal models, to bridge the translational gap between basic research and the clinic. Herein, we propose a novel approach in analysis of cell transplantation effects in large animals explants using in vi

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OBJECTIVES: Estimate risks of coronary heart disease (CHD), stroke and cardiovascular disease (CVD) with updated mean systolic (SBP) and diastolic (DBP) blood pressure in an observational study of patients with type 2 diabetes. METHODS: Thirty-five thousand and forty-one patients treated with antihypertensive drugs, and 18 512 untreated patients, aged 30-75 years, without previous heart failure,

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Acute lung injury (ALI) represents an aetiologically diverse form of pulmonary damage. Part of the assessment and diagnosis of ALI depends on skilled observer-based scoring of brightfield microscopy tissue sections. Although this readout is sufficient to determine gross alterations in tissue structure, its categorical scores lack the sensitivity to describe more subtle changes in lung morphology.

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Objective To review the efficacy of exercise interventions on sport-related concussion (SRC) incidence, as well as on linear and rotational head accelerations, and isometric neck strength and to assess reporting completeness of exercise interventions using the Consensus on Exercise Reporting Template (CERT).Design Systematic review and meta-analysis, according to the Prisma in Exercise, Rehabilita

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Studier i svensk språkhistoria 8 är en rapport från konferensen Svenska språkets historia 8 som avhölls i Lund 21-22 maj 2004. Temat för konferensen var Språkförändring på olika nivåer i språket. Tanken var att fokusera på språkförändringsmekanismer i ett brett perspektiv och på alla språkliga nivåer. I detta syfte hade konferensen fyra plenarföreläsningar; en vardera inom fonologi, lexikon, synta

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Chiral building blocks are needed in the chemical and pharmaceutical industries for the production of fine chemicals and pharmaceuticals. The utilisation of microorganisms and enzymes to perform stereoselective reductions of carbonyl compounds is an efficient and widely applied method for the generation of chiral molecules. The aim of this thesis was to develop and improve yeast-catalysed bioredu

Publication In EMBO Journal

Activation of endogenous retroviruses during brain development causes an inflammatory response Article Activation of endogenous retroviruses during brain development causes an inflammatory response Marie E Jönsson1 , Raquel Garza1 , Yogita Sharma1, Rebecca Petri1 , Erik Södersten2, Jenny G Johansson1, Pia A Johansson1 , Diahann AM Atacho1, Karolina Pircs1 , Sofia Madsen1, David Yudovich3, Ramprasa

https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/2021-03/publication%20in%20EMBO%20journal.pdf - 2026-07-23

Ana Rebordão

Sometimes it ends with a kiss Ana Rebordão creates staged environments in which she always plays the central figure, shifting between roles. Her latest piece, Sometimes it ends with a kiss, reflects on power relations within family structures. Through absurd, enigmatic performances, she evokes a sense of trauma and gives a sharp voice to silent female characters. The work shows women speaking to t

https://www.iac.lu.se/ana-rebordao - 2026-07-21

Geographies of Sustainability

MESS23, 7.5 credits The Geographies of Sustainability course provides interdisciplinary perspectives aimed at studying the dynamics of social and environmental change in particular places. The course covers perspectives from a variety of research fields from land-change science and landscape geography to political economy and cultural geography. It aims to advance students’ understanding of the sp

https://www.lumes.lu.se/programme-overview/programme-outline/2nd-semester/geographies-sustainability - 2026-07-21

Q&A: Search and write

17 September 2026 15:30 to 16:15 | Other Do you have questions about writing, texts, information retrieval or references? Let us help you! Almost every Thursday afternoon during the autumn term, you can meet librarians from the Library of Science and a language and study consultant from the Academic Support Centre in Zoom. We’re available online for anyone who wants to ask questions or get support

https://www.science-library.lu.se/calendar/qa-search-and-write - 2026-07-21

Q&A: Search and write

24 September 2026 15:30 to 16:15 | Other Do you have questions about writing, texts, information retrieval or references? Let us help you! Almost every Thursday afternoon during the autumn term, you can meet librarians from the Library of Science and a language and study consultant from the Academic Support Centre in Zoom. We’re available online for anyone who wants to ask questions or get support

https://www.science-library.lu.se/calendar/qa-search-and-write-0 - 2026-07-21

Q&A: Search and write

1 October 2026 15:30 to 16:15 | Other Do you have questions about writing, texts, information retrieval or references? Let us help you! Almost every Thursday afternoon during the autumn term, you can meet librarians from the Library of Science and a language and study consultant from the Academic Support Centre in Zoom. We’re available online for anyone who wants to ask questions or get support wi

https://www.science-library.lu.se/calendar/qa-search-and-write-1 - 2026-07-21

Q&A: Search and write

8 October 2026 15:30 to 16:15 | Other Do you have questions about writing, texts, information retrieval or references? Let us help you! Almost every Thursday afternoon during the autumn term, you can meet librarians from the Library of Science and a language and study consultant from the Academic Support Centre in Zoom. We’re available online for anyone who wants to ask questions or get support wi

https://www.science-library.lu.se/calendar/qa-search-and-write-2 - 2026-07-21

Q&A: Search and write

15 October 2026 15:30 to 16:15 | Other Do you have questions about writing, texts, information retrieval or references? Let us help you! Almost every Thursday afternoon during the autumn term, you can meet librarians from the Library of Science and a language and study consultant from the Academic Support Centre in Zoom. We’re available online for anyone who wants to ask questions or get support w

https://www.science-library.lu.se/calendar/qa-search-and-write-3 - 2026-07-21