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Defining extended half-life rFVIII-A critical review of the evidence

Introduction: Recent haemophilia treatment advances include new recombinant FVIII (rFVIII) products with improved pharmacokinetic (PK) properties that aim to reduce the burden of prophylaxis. These treatments are commonly referred to as extended half-life rFVIII products (EHL rFVIII). There is no uniform definition of what constitutes an EHL rFVIII. Such a definition would help physicians, patient

γ-globulins prepared from sera of multiparous women bind anti-HLA antibodies and inhibit an established in vivo human alloimmune response

It has previously been shown that sera from multiparous women have increased levels of anti-idiotypic antibodies specific for anti-HLA molecules. γ-Globulins prepared from these sera may be superior to commercial preparations of intravenous γ-globulin (IVIg) for inhibiting HLA alloimmunization. To test this, F(ab′)2 fragments prepared from either commercial IVIg or from the sera of men or multipar

Genetic signature of prostate cancer mouse models resistant to optimized hK2 targeted α-particle therapy

Hu11B6 is a monoclonal antibody that internalizes in cells expressing androgen receptor (AR)-regulated prostate-specific enzyme human kallikrein-related peptidase 2 (hK2; KLK2). In multiple rodent models, Actinium-225-labeled hu11B6-IgG1 ([225Ac]hu11B6-IgG1) has shown promising treatment efficacy. In the present study, we investigated options to enhance and optimize [225Ac]hu11B6 treatment. First,

Tissue deposits of IgA-binding streptococcal M proteins in IgA nephropathy and Henoch-Schonlein purpura.

IgA nephropathy (IgAN) and Henoch-Schönlein purpura (HSP) are diseases characterized by IgA deposits in the kidney and/or skin. Both may arise after upper respiratory tract infections, but the pathogenic mechanisms governing these diseases remain unclear. Patients with IgAN (n = 16) and HSP (n = 17) were included in this study aimed at examining whether IgA-binding M proteins of group A streptococ

TFPI-2 protects against gram-negative bacterial infection

Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Recently we reported that EDC34, a C-terminal peptide derived from TFPI-2, exerts a broad antimicrobial activity. In the present study, we describe a previously unknown antimicrobial mode of ac

C-terminal TFPI-1-derived peptides: their evolutionary host defense functions

Antimicrobial peptides (AMPs) are evolutionarily ancient molecules. They are essential innate immune response molecules that protect organisms from invading pathogens. Tissue factor pathway inhibitors (TFPI-1 and TFPI-2) C-terminal derived peptides exert host defense mechanisms against microbes. Studies showed that in human plasma, C-terminal TFPI-1 and -2 derived peptides mediate bacterial killin

Tentaschema VT 2026 Februari - Augusti 2026 Extern Hemsida 2025-12-08

Institutionen för handelsrätt Uppd: 2025-12-08 Tentamensschema februari 2026 - augusti 2026 Datum Kurskod Kursnamn Tid Lokal Tors 12 feb HARN53 Trade, Investment and Sustainability 14-19 MA9 HARN54 Intellectual Property and Trade Ons 25 feb HARA71 Kommersiella avtal och köp 14-19 MA8 HARG15 Compliance och risk i affärslivet HARA61 Dataskyddsrätt II HARA23 Förvaltningsrättslig översiktskurs HARA65

https://www.ehl.lu.se/sites/ehl.lu.se/files/2025-12/Tentaschema%20VT%202026%20%20februari%20-%20augusti%202026%20extern%20hemsida%202025-12-08.pdf - 2026-05-09

Moving (together) Matters How Synchrony Shapes Our Interactional Experience With Social Robots - 18

Moving (together) matters how synchrony shapes our interactional experience with social robots Valentina Fantasia SITE research group and Robotic lab, Department of Philosophy and Cognitive Science Synchrony is a hard-wired sociality mechanism in humans 3 • Evident in pre-natal and post natal coordination • Twin foetuses make special twin-directed movements distinct from movements toward inanimate

https://www.ai.lu.se/sites/ai.lu.se/files/2026-03/Moving%20(together)%20matters%20how%20synchrony%20shapes%20our%20interactional%20experience%20with%20social%20robots%20-%2018%20March%202026.pdf - 2026-05-09

Schema vårterminen 2013

Schema vårterminen 2013 Rev 160425 Schema Mediehistoria vårterminen 2016 MHIA12 Mediehistoria: Fortsättningskurs, 31-60 hp Delkurs 4: Uppsats, 7,5 p Kursansvarig: Sophie Elsässer Datum Tid Lokal Undervisning Lärare Mån 2/5 10–12 H405 Idéseminarium SE Mån 2/5 13–15 B210, Informationssökning, ES PC-sal steg 2 med bibliotekarie Obligatoriskt! Ons 4/5 13–14 A320 SI JW Fre 6/5 12.00 Inlämning av PM på

https://www.historiska.lu.se/media/utbildning/dokument/kurser/MHIA12/20161/MHIA12_dk4_vt16_schema_rev160425.pdf - 2026-05-08