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BackgroundA novel non-invasive method for generation of pressure volume loops (PV-loops) using brachial blood pressure and cardiovascular magnetic resonance (CMR) imaging has recently been presented and validated (1). The non-invasive nature of this method enables calculation of PV-loops in large patient cohorts previously not feasible due to the need of invasive measurements.PurposeThe purpose of
Background Sometimes, patients with a history of metal intolerance react negatively or doubtfully to nickel at patch testing. Objective The aim of the study was to investigate whether aqueous nickel sulfate hexahydrate at 15% and 30% traces more contact allergy than the nickel preparation in the baseline series at 5%. Methods In the period 1995-2015, more than 800 of 16,059 patients with a negativ
Background: Mass screening could identify those with unrecognized celiac disease (CD), but the experience of being detected through screening and living with screening-detected CD should be explored before considering this as acceptable intervention. For this study we invited screening-detected adolescents to describe their experience living with screening-detected CD five years after diagnosis wi
Background: The objective of this study was to determine whether the frequency of sexually transmitted diseases (STDs) and some reproductive events in women with experience of casual travel sex (CTS) abroad with previously unknown male partners differed when compared to women lacking such experience. Methods: Nine hundred and ninety-six women seeking contraceptive advice from two family planning c
Streptococcus bovis/Streptococcus equinus complex (SBSEC) is a common cause of infective endocarditis (IE). For IE-pathogens, the capacity to activate and aggregate platelets is believed to be an important virulence mechanism. While the interactions between bacteria and platelets have been described in detail for many Gram-positive pathogens, little research has been carried out with SBSEC in this
Bacteria can cause life-threatening infections, such as pneumonia, meningitis, or sepsis. Antibiotic therapy is a mainstay of treatment, although antimicrobial resistance has drastically increased over the years. Unfortunately, safe and effective vaccines against most pathogens have not yet been approved, and thus developing alternative treatments is important. We analyzed the efficiency of factor
BACKGROUND. This study was performed in women who had attended the clinic for contraceptive advice to determine whether a history of casual sex with a foreign male, previously unknown to them (SFM) in their home country (Sweden), constituted an increased risk for acquiring sexually transmitted diseases (STD) as compared to women without such an experience (COMP). METHODS. Of 996 women enrolled, an
OBJECTIVE: To describe and enhance our understanding of how persons with late effects of polio experience the influence of an interdisciplinary rehabilitation programme. PARTICIPANTS: Twelve persons with clinically verified late effects of polio who had participated in an individualized, goal-oriented, comprehensive interdisciplinary rehabilitation programme. METHODS: Qualitative research intervie
In this group we study how metastatic processes depend on suppression of the immune response and how the immune system actually instead promotes breast cancer metastasis. The research has a strong translational character with clinical collaborations and primary material as base in all projects. The focus is on immunosuppressive cell populations and metastatic processes in breast cancer. Understand
Our research is focused on the regulation of the complement system in health and disease. Complement is crucial part of innate immunity and thus protects host from infections and contributes to removal of dying cells. We study involvement of complement in pathology of rheumatic and inflammatory diseases as well as several types of cancer. Further, we investigate strategies developed by bacterial
We study the extension of what class of linear time invariantplants may be transformed into SPR systems introducingan observer. It is shown that for the open loopstable systems a cascaded observer achieves the result.For the open loop unstable systems an observer-basedfeedback is required to success. In general any system stabilizableand observable may be transformed into an SPRsystem. This overco
The function of six porcine left lung allografts was studied after pulmonary (140 mL/kg) and bronchial (50 mL/kg) artery perfusion with Perfadex (Kabi Pharmacia, Uppsala, Sweden) at room temperature, followed by 24-hour storage of the lungs in an atelectatic state in 6 degrees to 8 degrees C Perfadex, which is a low-potassium-dextran solution. Left lung transplantation was done followed by right p
