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Background: Sports function and psychological readiness to return to sports (RTS) are important outcomes when evaluating rehabilitation after anterior cruciate ligament reconstruction (ACLR). It is, however, unclear which specific factors contribute most to these outcomes. Purpose: To determine associations between demographic characteristics, objective measurements of physical function, patient-r

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Background: Retrospective comparative studies suggest a survival benefit after complete local treatment of recurrence (LTR) in renal cell carcinoma (RCC), which may be largely due to an indication bias. Objective: To determine the role of LTR in a homogeneous population characterised by limited and potentially resectable recurrence. Design, setting, and participants: RECUR is a protocol-based mult

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IMPORTANCE: The introduction of solid or semisolid foods alongside breast milk plays a vital role in meeting nutritional requirements during early childhood, which is crucial for child growth and development. Understanding the prevalence of zero-food children (defined for research purposes as children aged 6 to 23 months who did not consume animal milk, formula, or solid or semisolid food during t

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Purpose: Glaucoma is a heterogeneous group of optic neuropathies that potentially may be associated with other cerebral neurodegenerative processes leading to dementia. However, prior studies have been inconsistent. We examined dementia risks after glaucoma diagnosis in a large population-based cohort. Design: National matched cohort study. Participants: A total of 324 730 persons diagnosed with g

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Background: Understanding the relationship among changes in Clinical Dementia Rating (CDR), patient outcomes, and probability of progression is crucial for evaluating the long-term benefits of disease-modifying treatments. We examined associations among changes in Alzheimer’s disease (AD) stages and outcomes that are important to patients and their care partners including activities of daily livin

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Uppskattningsvis ligger idag mellan 2,5 till 20 miljoner ton olja i vrak runt världens kuster. Under tusentals år har den kommersiella sjöfarten dominerat haven. Det var dock inte förrän industrialiseringen på 1800-talet som olja började användas i allt större utsträckning. I den kommersiella sjöfarten är frakt av miljöfarliga ämnen inte något ovanligt, varje dag skeppas cirka en halv miljon ton oCurrently, between 2,5 and 20 million tons of oil are found in shipwrecks around the world. For thousands of years, commercial sea transport has dominated the seas. However, it was not until the industrial revolution in the 19th century that oil started being used extensively. Within commercial sea transport, the shipping of environmentally hazardous substances is not uncommon. About half a millio

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Jordan has one of the lowest available water supplies in the world; meanwhile Jordan has seen large increase in population and refugee’s fluxes, leading to an increase in water demand [1]. To address this unprecedented water scarcity, Jordan’s water must be used where its social and economic value is highest. Jordan must treat and reuse virtually every drop of water. It is expected to have more th

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BACKGROUND: Atrioventricular plane displacement (AVPD) reflects longitudinal left ventricular (LV) systolic function, and wall thickening (WT) regional radial LV function. The temporal evolution of these measures after STEMI with CMR has not been evaluated. We aimed to investigate how AVPD and WT are affected globally and regionally from the sub-acute to the chronic phase after ST-elevation myocar

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We studied avian development in 49 to 153 species of temperate and tropical New World passerine birds to determine how growth rates, and incubation and nestling periods, varied in relation to other life-history traits. We collected growth data and generated unbiased mass and tarsus growth rate estimates (mass n = 92 species, tarsus n = 49 species), and measured incubation period (n = 151) and nest

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Background: Low levels of the soluble tumour necrosis factor-like weak inducer of apoptosis (sTWEAK) and depression are linked to cardiovascular disease. Galectin-3, inadequate glycemic control and low high-density lipoprotein (HDL)-cholesterol levels were previously linked to depression in these patients with type 1 diabetes mellitus (T1DM). The main aim was to explore whether sTWEAK was associat

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The transition from animal-based to plant-based proteins is rapidly increasing because of different concerns about meat consumption, some being the nutritional and environmental effects of meat consumption. During this transition, there needs to be a holistic approach to assessing plant-based food. This master thesis is focused on investigating the nutritional and environmental impact of three pla

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Antibiotic resistance poses a global threat. Antibiotics are administered to 80-90% of terminally ill patients but evidence of their effectiveness in improving survival or symptom relief at the end of life (EOL) is scarce. To determine the proportion of deceased patients that continue antibiotic treatment after documented EOL discussion and the decision to prioritise symptom relief over active tre

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Quantification using the Centiloid (CL) scale has become a valuable information to consider when interpreting amyloid-PET images and is now implemented in several software packages. This work aims to assess the comparability of CL from [18F]flutemetamol scans derived using several research and commercial quantification pipelines. Methods: This analysis relies on three datasets: a test-retest cohor

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BACKGROUND: Long COVID has emerged as a global health challenge, with increasing evidence of cardiovascular sequelae. Most previous studies have focused on hospitalised cohorts, whereas cardiovascular risk in community-managed long COVID cases remains less explored. We aimed to investigate the incidence of major cardiovascular events in individuals with long COVID compared to those without long CO

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Background: Knowledge is increasing about TSC-Associated Neuropsychiatric Disorders (TAND), but little is known about the potentially confounding effects of intellectual ability (IA) on the rates of TAND across age, sex, and genotype. We evaluated TAND in (a) children vs. adults, (b) males vs. females, and (c) TSC1 vs. TSC2 mutations, after stratification for levels of IA, in a large, internationa

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Apart from the substantive public procurement rules, harmonising national provisions for the award of public contracts, the Community also strives to ensure compliance with those rules. For that purposes the Remedies Directive 89/665/EEC has been adopted to ensure that effective and rapid remedies are available to aggrieved bidders. This directive has recently been amended by Directive 2007/66/EC

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The regulation of the European parliament and the Council (EG) nr. 864/2007 on the law applicable to non-contractual obligations is known as Rome II. Rome II contains a conflict rule in art. 7 which determines the law applicable to a claim involving environmental damages connected with more than one state. This conflict rule does not only apply to cases of damage to property and persons, but also

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Childhood cancer aetiology is poorly understood and is considered to originate in utero and early postnatal life. In this study, we investigated perinatal characteristics as potential risk factors by performing a population-based case-control study, including 1340 cancer cases diagnosed < 19y and born between 1989–2021 in southern Sweden, and 13400 controls matched by sex, year, and municipality o

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Biodiversity hotspots are biogeographic regions exceptionally rich in endemic species showing high rates of habitat loss, making them the priority of global conservation efforts. As part of the biodiversity hotspot with the highest density of endemic species, the West Usambara Mountains in Tanzania require an efficient and resourceful monitoring solution. This thesis aimed to model the tree specie