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Background: Botulinum toxin A (BTX-A) has been used to reduce spasticity in children with cerebral palsy (CP) for decades. The purpose of this study was to analyze to what extent BTX-A treatment was used to treat spasticity in a total population of children with CP. We investigated 1) the use of BTX-A in relation to age, sex, and Gross Motor Function Classification System (GMFCS) level, 2) the mos
Background: Chronic pain patients frequently suffer from psychological symptoms. There is no consensus concerning the prevalence of severe anxiety and depressive symptoms and the strength of the associations between pain intensity and psychological distress. Although an important aspect of the clinical picture is understanding how the pain condition impacts life, little is known about the relative
In the central Himalayas, water dynamics are expected to change due to multiple factors like climate change, hydro power development and shifting land use practices. This thesis looks at possible changes in water dynamics in Marsyandi river basin, Nepal, as well as causes to those changes and how they are perceived locally. Grounded in critical physical geography, the study uses mixed methods an
This is a thesis project, analysing data from high-resolution imaging observations, specifically speckle imaging, as a follow up study of exoplanet host stars observed with K2, the second operational phase of the space telescope Kepler. The project was accomplished at NASA Ames research center under the guidance of Rachel A. Matson, during an internship in collaboration with the Swedish National S
Popular Abstract in Swedish Streptococcus pyogenes Människan är ständigt koloniserad av en mängd olika mikroorganismer. De flesta bakterier är ofarliga och en del av dem är faktiskt nödvändiga för oss, t.ex. de tarmbakterier som hjälper oss att producera vitaminer. Grupp A streptokocker (GAS) eller Streptococcus pyogenes, är en av de vanligaste sjukdomsframkallande bakterierna hos människan. De kaWe have found that a set of group A streptococcal strains, primarily associated with skin infections, express surface-associated M proteins that bind plasminogen and plasmin with high affinity. The binding is mediated by a common 13 amino acid internal repeated sequence located in the NH2-terminal surface-exposed portion of these M proteins. It could be demonstrated that plasminogen, absorbed by t
The university programmes are basically nationally based, developed from the historical needs of specific need of a society. The Bologna process is challenging the educational market mainly at post-graduate level. The exchange of students is still limited to a reduced number of curious and ambitious persons, many with a high interest for cultural exchange – the ‘exotic dimension’. Individual caree
Background One of Alfa Laval’s factories in Lund, LA, has noticed that up to 50% of all order proposals suggested by their ERP system JEEVES is considered to be irrelevant and are subsequently disregarded by the purchasers. Consequently, many purchasers disregard the parameters in JEEVES that control what proposals get suggested and instead order on “gut-feeling” and personal experience. Not only
The title of this Master´s thesis is Multicultural librarian competence - a literature study and interwievs with librarians and managers in Malmö Public Library. Every fifth Swede is born abroad or has at least one parent who are. The migration flows of today reach out longer, there are more efficent ways of communication and travel. This has made previously ethnic homogeneous populations as the
Strategic decisions on how a company should invest resources is naturally a crucial decision, but for startups this decision is even more important as each small decision will have major repercussions on the longevity of a startup. This study seeks to deepen the understanding of the perceived sustainability of a startup by a customer - since this is a growing customer decision criteria - and h
OBJECTIVE: This study assessed prognostic factors regarding long-term outcome for amputation and death among patients who underwent intra-arterial thrombolysis due to lower limb ischemia. METHODS: Consecutive patients with intra-arterial thrombolysis due to lower limb ischemia treated at the Department of Vascular Diseases, University Hospital of Malmö, between January 1, 2001, and December 31, 20
OBJECTIVE: To investigate effects of lipid lowering drug, simvastatin, on apolipoprotein M expression in the hyperlipidemic mice and in hepatic cell line, HepG2 cells. METHODS: Swiss male mice were randomly divided into the high fat group and control group, and were intragastrically fed with 0.9% saline (control group) or lipid emulsion (high fat group) at the daily dosage of 15 ml/kg body weight
Deteriorating water quality is a challenge which affects people of the entire world, with a growing population and increased industrialization worldwide. The problem is especially apparent in many developing nations where water resource management must be improved to secure a future sustainable supply. This study was undertaken as a bachelor degree within the MFS-program funded by SIDA. The study
Outdoor climate has considerable impact on the indoor climate and it is therefore important to adapt the buildings to the climate. This thesis shows how to improve indoor climate in a climate which it is hot, dry in the summer and cold in the winter. My investigative unit is a middle class house in the town Baalbek in Lebanon and the purpose of the study is to come up with proposals on possible so
Right now, the world is facing the largest wave of urban growth in history. The cities depend on nature’s ecosystem to function properly. The aim is to build dense, green and sustainable. In the future we must find new ways to integrate green structure into the cities more efficiently. Green to Grey is a series of paving stones that can host vegetation. The product and the vegetation can flexibly
Background: Somali piracy and armed robbery against ships remain to be one of the major global concerns today. Since 2007, over 1,500 piracy and piratical attacks were reported to the IMB Piracy Reporting Centre. These figures were gradually increased over the years, along with the degree of maritime violence. Somali pirates, with the urge of ransom payments, have consequently become more threate
Medgärningsmannaskapet är en komplex rättsfigur som både tillämpats och kommit till uttryck på olika sätt. Det är en oförutsägbar konstruktion och därför intressant att studera och lätt att kritisera. Uppsatsens syfte är att redogöra för medgärningsmannaskapets rättsliga stöd, tillämpning och uttryck samt huruvida konstruktionen tillämpats i linje med en sådan medverkanslära som StraffrättskommiIn Sweden there is a complex legal construction called “medgärningsmannaskap” (perpetrators of parties to a crime) that is both applied and expressed in many different ways. It is an unpredictable unit in the Swedish legal system and thus interesting to study and easy to criticize. The purpose of this thesis is to describe on what legal foundation “medgärningsmannaskapet” is built upon, how it is
Background: Paediatric surgical care is increasingly being centralized away from low-volume centres, and prehospital delay is considered a risk factor for more complicated appendicitis. The aim of this study was to determine the incidence of paediatric appendicitis in Sweden, and to assess whether distance to the hospital was a risk factor for complicated disease. Methods: A nationwide cohort stud
Background and Purpose- Psychosocial factors can have implications for ischemic stroke risk and recovery. This study investigated the effect of genetically determined risk of depression on these outcomes using the Mendelian randomization (MR) framework. Methods- Genetic instruments for risk of depression were identified in a discovery genome-wide association study of 246 363 cases and 561 190 cont
Anaplastic thyroid cancer (ATC) is a rare and highly aggressive thyroid malignancy, usually resistant to conventional therapeutic strategies. The prognosis of ATC is extremely poor with a median survival rate of 6 months. Current treatment therapy includes surgical resection in combination with external radiotherapy and chemotherapy. The underlying mechanisms involved in ATC tumorigenesis is under
The sharing economy is an emerging niche for innovation capable of disrupting established socio-technical and economic regimes. Because of this potential to cause radical changes in a wide array of domains, research in multiple disciplines addressing various aspects entailing this phenomenon is proliferating. In this emerging body of literature, the understanding and framing of the sharing economy
