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Strålbehandling är en av de vanligaste metoderna för att behandla cancer. I den mest använda formen av strålbehandling används en strålkälla utanför kroppen, så kallad extern strålterapi. Ett alternativ är att ge behandlingen med hjälp av ett läkemedel till vilket man har kopplat ett radioaktivt ämne, så kallad radionuklidterapi. Det radioaktiva läkemedlet ansamlas i tumören och ger där en intern In radionuclide therapy (RNT), radioactive pharmaceuticals are administered for therapeutic purposes. Dosimetry, i.e. the estimation of the absorbed dose to various targets, can potentially lead to a better understanding of the therapeutic effects in RNT and allow for individualization of the therapy. However, dosimetry is seldom used in RNT clinical practice, and several problems degrade the info

This paper analyses the effect of variety and intensity of knowledge on the innovation of regions. Employing data for Swedish functional regions, the paper tests the role of the variety (related and unrelated) and intensity of (1) internal knowledge generated within the region and also (2) external knowledge networks flowing into the region in explaining regional innovation, as measured by patent

Douglas-Rachford splitting and the alternating direction method of multipliers (ADMM) can be used to solve convex optimization problems that consist of a sum of two functions. Convergence rate estimates for these algorithms have received much attention lately. In particular, linear convergence rates have been shown by several authors under various assumptions. One such set of assumptions is strong

This paper presents a new microphone array method to enhance speech signals in a noisy reverberant environment. A time-delay estimation method is used for the speech source localization. The robustness of the localization method in high noise levels is provided by a subband Kurtosis-weighted structure. The estimated inter-sensor time-delays are directly used in an adaptive soft-constrained subband

In this chapter, speech enhancement and echo cancellation for hands-free mobile telephony are discussed. A number of microphone array methods have been tested and results from car measurements are given. Traditional methods such as linearly constrained beamforming and generalized sidelobe cancelers are discussed as well as array gain optimization methods. An in situ calibrated method which gives a

The linear filtering, prediction and smoothing problems as well as the linear quadratic control problems can very generally be formulated as operator equations using basic linear algebra.The equations are of Fredholm type II, and they are difficult to solve directly.It is shown how the operator can be factorized into two Volterra operators using a matrix Riccati equation. Recursive solution of the

We provide necessary and sufficient structural conditions for multistationarity and oscillations in aggregate monotone systems, defined as the interconnection of stable monotone components. Our classification is based on the presence of exclusively positive or exclusively negative cycles in the system aggregate graph, whose nodes are the monotone subsystems. The results presented here scale up the

Synovial proliferation in rheumatoid arthritis causes capsular distension, destruction of tendons and ligaments, and erosion of bone. The classic deformities in rheumatoid arthritis, like boutonnière or swan neck, are not consistent, and each patient may have his or her own pattern of deformities. The anatomic arrangement of the tendons enables motion of the proximal interphalangeal (PIP) joint is

We present a study of the performance degradation of electromagnetic absorbers when applied to doubly curved surfaces. The scattering from a perfectly conducting sphere coated with different types of single- and multilayer absorbers has been evaluated using analytic recursion expressions. A comparison of the effect of curvature on the absorber performance is presented for structures based on homog

A large-scale, high-efficiency and low-cost platform based on a Beckman Coulter Biomek FX and custom-made automation systems for structural genomics has been set up at Peking University, Beijing, People's Republic of China. This platform has the capacity to process up to 2000 genes per year for structural and functional analyses. Bacillus subtilis, a model organism for Gram-positive bacteria, and

Oats are an excellent source of high-quality proteins, with a favourable amino acid composition. Oat proteins therefore have greatpotential to complement existing animal and plant protein sources, especially if the protein content could be increased. In this thesis,high-protein oat lines were identified and characterised. More than a thousand individual lines in a mutagenised oat population(Target

In multipath routing, maximization of the cardinality K of the disjoint-path set for a given source and destination assuming an upper bound on the differential delay D is one of the key factors enabling its practical applications. In the paper we study such an optimization problem for multipath routing involving maximization of K under the D constraint as the primary objective, and then minimizati

The combination of complementary measurement techniques has become a frequent approach to improve scientific knowledge. Pairing of the high lateral resolution scanning force microscopy (SFM) with the spectroscopic information accessible through scanning transmission soft x-ray microscopy (STXM) permits assessing physical and chemical material properties with high spatial resolution. We present pro

The European Spallation Source is Europe's next generation high-power neutron source utilising a linear accelerator and a rotating tungsten target to produce neutrons that will be used for fundamental research and industrial applications. The facility is co-hosted by the states of Denmark and Sweden, and while the main site will be placed in Lund, Sweden, the Data Management and Software Centre wi

Graphene's success has stimulated great interest and research in the synthesis and characterization of graphene-like 2D materials, single and few-atom-thick layers of van der Waals materials, which show fascinating and technologically useful properties. This review presents an overview of recent electrochemical sensors and biosensors based on graphene and on graphene-like 2D materials for biomarke

The value of course evaluations has been debated since they frequently fail to capture the complexity of education and learning. Group Concept Mapping (GCM), a participant-centred mixed-method was explored as a tool for evaluation and development in nursing education and to better understand students' learning experiences, using data from a GCM-based evaluation of a research training assignment in

A smart power management strategy is needed to economically manage local production and consumption while maintaining the balance between supply and demand. Finding the best-distributed generators’ set-points and the best city demand scheduling can lead to moderate and judicious use out of critical moments without compromising smart city residents’ comfort. This paper aimed at applying the Particl