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Changes in the LIS Research Front: Time-Sliced Cocitation Analyses of LIS Journal Articles, 1990–2004

Based on articles published 1990-2004 in 21 LIS journals, a set of co-citation analyses were performed to study changes in research fronts over the last 15 years, where LIS is at now; and to discuss where it is heading. To study research fronts, here defined as current and influential co-cited papers, a citations among documents methodology was applied; and to study changes, the analyses were time

Konstruktion av doseringssystem för tillsatsämne till dieselpump

This thesis describes the development process of an additive dosage system for a fuel dispenser. The level of additive concentration is low (<1000 ppm) and three predefined concentration levels are selectable for each filling. A device to visualize the additive dosing, when chosen, was also required. These prerequisites influenced the decision to design a separate additive system for pumping, mete

“Brown Babies” in post-WWII Denmark : A Case Study of the Vulnerabilities of Adopted Children Born of War

Children born to occupying soldiers during or after conflicts are in many ways an extraordinarily vulnerable population. These so-called children born of war (CBOW) commonly inherit the stigma of transgression and foreignness from their respective parents and face discrimination in post-conflict societies. Their specific vulnerabilities, though, emerge from multiple overlapping factors: the needs

A fork in the road : – why CC BY?

As academic librarians at a medical faculty, we promote open science practices by educating researchers about the implications of open license conditions. Researchers are sometimes faced with a choice of path in the process of publishing open access, when the publisher offers a choice of different Creative Commons licenses. They are often not aware of what the terms of the licenses mean in practic

”Grift-Runor, skrifne 1769" : En ärekränkande och blasfemisk gravdikt av Brynolph Hallborg

The seventeenth and eighteenth centuries are the golden age of the poetic epitaph in Sweden and Europe. Most epitaphs were shaped in accordance with the principle of decorum, i.e., they were written to praise the dead and to comfort the bereaved. But there were also poems that sought to instead find faults with the deceased, sometimes even to insult their memory. A form of funeral poetry that was

Identifying bacteria using DNA binding maps

We have developed an assay, based on nanofluidic channels and fluorescence microscopy, for optical mapping of DNA based on competitive binding between two molecules - one fluorescent and one sequence selective. From the experimental data we can extract binding constants for the two competing DNA binders, which may be subsequently used to calculate a theoretical reference map of any DNA with known

Sample preparation for single-cell whole chromosome analysis

In this work we present an integrated system for whole chromosome analysis of single bacterium. Using whole genome barcoding techniques, which offer direct and rapid microscopic visualization of the entire genome in one field-of-view, we aim to rapidly identify individual bacterium. We are developing our device to achieve the crucial, and difficult process of isolating a bacterium, removing the DN

Beta secretase 1-dependent amyloid precursor protein processing promotes excessive vascular sprouting through NOTCH3 signalling

Amyloid beta peptides (Aβ) proteins play a key role in vascular pathology in Alzheimer’s Disease (AD) including impairment of the blood–brain barrier and aberrant angiogenesis. Although previous work has demonstrated a pro-angiogenic role of Aβ, the exact mechanisms by which amyloid precursor protein (APP) processing and endothelial angiogenic signalling cascades interact in AD remain a largely un

Aquaporins : Chemical inhibition by small molecules

The human genome encodes 13 aquaporin isoforms with characteristic substrate specificity that are expressed at specific locations throughout the body. Of these isoforms, AQPs 1-4 serve important functions in renal water reabsorption. Consequently, specific AQP inhibitors have been proposed as 'aquaretics', a new class of drugs suitable to induce diuresis without concomitant salt wasting. Furthermo

Dynamic site characterization for brownfield risk management

Common remediation and land management approaches often preclude economically attractive and low risk brownfield redevelopment. The authors argue that recently developed dynamic site characterization techniques can greatly improve sound decision making on land revitalization options. A number of these in-situ soil and groundwater test methods, such as MIP, ROST™/UVOST™, XRF and BAT, based on geote

Fate of riverine iron over estuarine salinity gradients

Floder och åar är viktiga källor för järn och andra näringsämnen till Östersjön. De senaste decennierna har järnkoncentrationen i svenska och finska åar ökat kraftigt, vilket skulle kunna leda till en ökad transport av järn till Östersjön. Vilken effekt detta kan ha för Östersjön beror på vad som händer med järnet när det möter det salta vattnet i Östersjön. Järn transporteras huvudsakligen i formRivers have traditionally not been considered important sources of bioavailable iron (Fe) to the marine waters, since most Fe is lost by salinity-induced aggregation and sedimentation during estuarine mixing. However, recent studies from boreal rivers found a remarkably high Fe stability, probably due to the interaction with organic matter. Recent studies have suggested that Fe speciation is a key

From space to specs : Requirements for 4MOST

4MOST,1 the 4m Multi-Object spectrographic Survey Telescope, is an upcoming optical, fiber-fed, MOS facility for the VISTA telescope at ESO's Cero Paranal Observatory (Chile). The preliminary design of 4MOST features 2,400 fibers split into a low-resolution (1,600 fibers, 390-900 nm, R > 5; 000) and a high-resolution channel (800 fibers, three arms, ∼20-25 nm coverage each, R > 18; 000) with an Ec