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Purpose: Radiotherapy (RT) for patients with locally advanced head and neck squamous cell carcinoma (LA-HNSCC) can be intensified by delivering 6 (6fx/w) instead of 5 (5fx/w) fractions per week. Randomized trials have demonstrated superiority for 6fx/w in patients treated without concurrent chemotherapy (CRT). This real-world analysis compares 6 vs 5 fx/w in LA-HNSCC all-comers, treated predominan
Introduction: Evidence for gut–kidney interactions in early kidney disease is limited, particularly in community-dwelling adults with largely preserved kidney function. Here, we quantified links between gut microbiota and estimated glomerular filtration rate (eGFR) in two population-based Swedish cohorts. Methods: Deep shotgun metagenomics profiled fecal samples from 9788 adults in the Swedish CAr
Rapid urban growth is making cities hotter, a trend further exacerbated by climate change. Urban green spaces (UGS) are commonly used as nature-based solutions to reduce heat, but there are gaps in understanding how cooling effects vary across climate zones. Using satellite data from 2021 to 2024, we examined urban heat and UGS patterns during the hot season across four Ethiopian cities with diffe
BACKGROUND/AIMS: This study represents an external validation with model updating of the online DIGIROP-Prescreen and DIGIROP-Screen 2.0 prediction models, incorporating ≥14 days of parenteral nutrition as an additional predictor, to identify infants requiring treatment for retinopathy of prematurity (ROP) in a contemporary Swedish cohort, estimate potential cost savings and compare DIGIROP perfor
The World Health Organization rapports general low adherence to medical treatments in long term therapies among developed countries. The aim of this study was to analyse the individual variation in drug adherence to long term use. A set of individual data with people interviewed in year 2004/2005 was created from the Swedish Survey of Living Conditions and the Pharmaceutical Registry. The data set
In February 2002, the UNITA rebel leader Jonas Savimbi was shot dead by Angolan Government forces, thereby putting an end to almost four decades of war in Angola. Once peace had been declared, the Government of Zambia together with the Government of Angola and the UNHCR began to make arrangements for the voluntary repatriation of the large Angolan refugee population residing in Zambia. However, du
The increasing spread of global pandemics such as HIV/AIDS, tuberculosis (TB) and malaria, in particular in developing countries, has forced the engagement of industrialized countries and pharmaceutical companies. Because medicines to cure these diseases are often under patent protection, they are not affordable for people in developing countries where health crises prevail. In November 2001, WTO
Human rights are the basis by which the dignity of the human being is guaranteed. This is especially important in the relationship between persons and governments, who on the one hand have great power in form of legislation over these persons, but on the other hand must ensure the protection of human rights. A problem may arise when these two opposing forces of the State collide,1 as the individua
Den samiska ursprungsbefolkningens traditionella territorium breder ut sig över delar av Sverige, Norge, Finland och Ryssland. Samisk kultur är starkt kopplad till rennäringen, som kräver vidsträckta och sammanhängande marker där renen ostörd kan få tillgång till naturbete. Den här uppsatsen undersöker nuvarande möjligheter för samer i Sverige att påverka beslutsprocesser rörande användning av marThe traditional territory of the indigenous Sami people stretches into Sweden, Norway, Finland and Russia. Sami culture is strongly connected to reindeer husbandry, which requires vast and coherent land where the reindeer can access natural pasture without disturbances. This thesis examines present possibilities for Sami in Sweden to impact decision-making processes regarding use of land and natur
Att vara ett offer för människohandel (trafficking) genom prostitution eller annan sexuell exploatering innebär att offret utsätts för uppenbara kränkningar av sina mänskliga rättigheter i form av våldtäkt, fysiskt våld, tvångsprostitution och sexuellt slavarbete. Efter att ha undkommit sin fångenskap är offret i stort behov av socialt och medicinskt stöd. Utöver detta kan det finnas ett stort behBeing a victim of trafficking for sexual purposes could mean being subject to the most flagrant human rights violations there is, such as forced prostitution, rape, physical violence and sexual enslavement. After escaping captivity, the victim needs both social and medical assistance. Additionally, a victim could have a strong desire to reside in the country where the exploitation has taken place
Today, investors look for more than just the potential return a company can bring when making investment decisions. An increased demand to invest sustainably has created a demand for investors to screen companies via ESG scores. In this thesis, we therefore aim to examine if Bloomberg’s ESG disclosure scores can be used as screening tools and proxies for the most common risk and return measures, v
The development and expansion of artificial intelligence have significant potential to benefit humanity; however, the risks posed by AI-related tools have also become a growing concern over the past decade. From the standpoint of human rights violations AI-related bias, discriminatory practices, data protection practices and violations or potential infringements on fundamental rights are some of t
Background: Rat pups are born with an immature intestine adapted for the effective uptake of milk nutrients and with high permeability for bioactive molecules from the maternal milk until weaning. During weaning the immune system is activated after stimulation with e.g. dietary antigens, leading to an inflammatory response in the gut. This response is believed to be important for progress of gut m
This thesis seeks to answer what causes some governments to restrict foreign funding to domestic civil society organizations while others do not. These repressive measures have increased significantly in all regions of the globe recently and existing research has yet to provide an encompassing explanation for the trend. Considering that neither foreign funding or government repression are exactly
Due to a warming climate, tundra ecosystems are subject to shrub and treeline expansions which could lead to increased above- but decreased belowground carbon (C) stocks. An observed low soil C stock in some subarctic forests and tall shrublands has been suggested to be induced by priming of organic matter decomposition, possibly mediated by ectomycorrhizal fungi. On the other hand, the higher bel
Previous studies have shown a correlation between nature connection and pro environmental behavior. Simultaneously, urbanisation amongst other causes has led to decreased human contact with nature. However, local outdoor recreation is considered an option for spending time in nature despite living in urban areas. Drawing from the above, there are reasons to study whether local outdoor recreation c
This study shows that several beneficial aspects of climate adaptation in Swedish municipalities can be linked to the United Nations’ sustainable development goals. In doing so, the study also exhibits that the sustainable development goals could serve as a good tool to aid in maximizing social, environmental and economic benefits when planning and executing climate adaptation measures. A claim th
Local acceptance is key when implementing climate technologies. One necessary technology to mitigate climate change is land-based Carbon Capture and Storage (CCS). In Denmark, earlier experience with the technology ended in shutdown due to local resistance. But now CCS plays a significant role in the Danish climate reduction goals; without CCS the goal won't be met. The academic field is very
Increased average temperatures, rising sea levels and heat waves are some examples of the consequences of climate change. Cities are particularly vulnerable to climate-related events due to their structure and lack of green and blue spaces causing negative impacts on both the environment and public health. Children are one of the most sensitive groups to heat waves and they spend plenty of time in
