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Background: Acute myeloid leukemia (AML) patients have limited effect from T-cell-based therapies, such as PD-1 and CTLA-4 blockade. However, recent data indicate that AML patients with TP53 mutation have higher immune infiltration and other immunomodulatory therapies could thus potentially be effective. Here, we performed the transcriptional analysis of distinct T-cell subpopulations from TP53-mu
Introduction: Over the past two decades, there has been a shift from concealing diagnoses of sex development from impacted people to the broad principle of age-appropriate disclosure. This change is consistent with children’s rights and with general shifts towards giving children medical information and involving patients in medical decision-making. The present paper examines how health profession
Increased understanding of the context and context adaptation is needed since effective change implementation and context are connected. This thesis begins to explore the role of context and context adaptation in traffic management change processes to increase knowledge on how organizational change can be managed more successfully.The empirical context for this thesis is The Swedish Transport Admi
There is limited understanding of how education initiatives geared toward faculty and support staff can foster a capacity for long-term and integrated societal engagement and collaboration within higher education institutions. Using the experiences from a cross-disciplinary pilot course in Sweden, the current study aims to identify features that explicate how skills and academic rigor for engaging
Background: Many children undergo various surgeries, which often lead to acute postoperative pain. This pain influences recovery and quality of life. Non-steroidal anti-inflammatory drugs (NSAIDs), specifically cyclo-oxygenase (COX) inhibitors such as diclofenac, can be used to treat pain and reduce inflammation. There is uncertainty regarding diclofenac's benefits and harms compared to placebo or
Audio description (AD) provides access to audiovisual materials for people with visual impairments and blindness (BVI) and offers a richer and more detailed understanding and experience. The cognitive approach to AD concerns perceptual, cognitive and meaning-making processes underlying production and reception of AD. By meaning-making, we mean multimodal textual and contextual processing, understa
Bästa resultat får du om du öppnar den här PDF-portföljen i Acrobat X eller Adobe Reader X eller senare. Hämta Adobe Reader nu! http://www.adobe.com/go/reader_download_se Postadress Box 117, 221 00 Lund Besöksadress Universitetshuset, Paradisgatan 2 Telefon 046-222 70 24, 046-222 00 00, 070-290 67 83 E-post cecilia.billgren@rektor.lu.se Univers i te ts ledningens kans l i Avdeln ingschef Cec i l i
https://www.lu.se/sites/www.lu.se/files/protokoll-och-bilagor-us-180216.pdf - 2026-06-23
A real-time kernel which supports concurrent programming in Pascal is described. It implements semaphores for mutual exclusion and events for other synchronization. The kernel also offers the possibility to program I/O handlers. The kernel is written in Pascal, but relies on a small number of assembly written procedures for process creation, transfer between processes and handling of interrupts. T
Carbon fiber reinforced plastics, CFRP, are attractive materials not only because of their strength and stiffness but also because of their electrical conductivity and high thermal conductivity and diffusivity. One application where induction heating of CFRP is particularly interesting is tools for fast thermal cycling, beneficial in many industrial processes, for example in composite manufacturin
Although legal contexts are subject to biased reasoning and decision making, to identify and test debiasing techniques has largely remained an open task. We report on experimentally deploying the technique “giving reasons pro et contra” with professional (N = 239) and lay judges (N = 372) at Swedish municipal courts. Using a mock legal scenario, participants assessed the relevance of an eyewitnessAlthough legal contexts are subject to biased reasoning and decision making, to identify and test debiasing techniques has largely remained an open task. We report on experimentally deploying the technique “giving reasons pro et contra” with professional (N = 239) and lay judges (N = 372) at Swedish municipal courts. Using a mock legal scenario, participants assessed the relevance of an eyewitness
Research shows that aid in many cases is given with a political strategy. Since aid is financed by taxpayers, we find it interesting and relevant to further investigate the political motives behind Swedish aid and if the focus of Swedish aid has differed across time and elected governments. The aim is to empirically investigate the role of the character of the recipient countries and the role of t
This thesis aims to study how the legitimacy of the EU’s pandemic crisis response in connection to green policies, in the interinstitutional exchange, is supported or undermined by connected frames and a subordinate master frame over the course of the first six months of the unfolding pandemic. Six EU institutions’ residents, who “have a say” on economic crisis measures, were picked from the Europ
