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Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Recently we reported that EDC34, a C-terminal peptide derived from TFPI-2, exerts a broad antimicrobial activity. In the present study, we describe a previously unknown antimicrobial mode of ac
Small synthetic ligands for protein purification have become increasingly interesting with the growing need for cheap chromatographic materials for protein purification and especially for the purification of monoclonal antibodies (mAbs). Today, Protein A-based chromatographic resins are the most commonly used capture step in mAb down stream processing; however, the use of Protein A chromatography
OBJECTIVE: Mapping coreceptor epitopes used by the prototypic R5 and X4 strains, HIV-1BaL and HIV-1IIIB, in comparison with epitopes involved in the activation and signaling induced by the natural ligands, RANTES and SDF-1beta. DESIGN: Receptor hybrids between CCR5 and CXCR4 were constructed. METHODS: Using single-overlap and extension PCR, increasing portions of CCR5 were replaced with correspond
The Malmö Diet and Cancer Study The Malmö Diet and Cancer Study Department of Clinical Sciences Skåne University Hospital, Malmö Lund University Malmö Diet and Cancer Study incl. CV-cohort Cardiovascular Endpoints End of follow-up: 31 December 2016 Report: 4 April 2018 Anders Dahlin Bo Hedblad (coronary events and stroke) Gunnar Engström (heart failure) Olle Melander (atrial fibrillation and flutt
https://www.malmo-kohorter.lu.se/sites/malmo-kohorter.lu.se/files/mdc_cardiovascular_endpoint_report_2017.pdf - 2026-07-07
Centre for Economic Demography Lund University School of Economics and Management P.O. Box 7080 SE-220 07 Lund, Sweden www.ed.lu/publications/Lund-Papers-in-Economic-Demography/ Ethnic Composition of Couples and Mutual Health Benefit Receipt: Register-Based Evidence from Finland JAN SAARELA, MARIA STANFORS, MIKAEL ROSTILA LUND PAPERS IN ECONOMIC DEMOGRAPHY 2021:3 http://www.ed.lu/publications/Lund
https://www.lusem.lu.se/sites/lusem.lu.se/files/2024-07/LPED_2021_3.pdf - 2026-07-07
The glycosylation status of IgG has been implicated in the pathology of rheumatoid arthritis. Earlier, we reported the identification of a novel secreted endo-beta-N-acetylglucosaminidase (EndoS), secreted by Streptococcus pyogenes that specifically hydrolyzes the beta-1,4-di-N-acetylchitobiose core of the asparagine-linked glycan of human IgG. Here, we analyzed the arthritogenicity of EndoS-treat
This study demonstrates that a cytotoxic serum reactivity not requiring the presence of complement appears in the sera of patients with acute myelogenous leukemia. The reaction is detected upon short‐term incubation of sera in vitro with autochthonous mononuclear white blood cells from peripheral venous blood of patients at the acute stage of the disease. This reactivity was demonstrated in 18/18
Primary immune thrombocytopenia is an autoimmune disease associated with a reduced peripheral blood platelet count. The phenotype is variable with some patients suffering no bleeding whilst others have severe bleeding which may be fatal. Variability in clinical behaviour and treatment responses reflects its complex underlying pathophysiology. Historically the management has relied heavily on immun
UC Study Plan UC STUDY PLAN Study plan for UC Indicate UC campus above. Complete one UC Study Plan form for each of the three UC campuses that you select. You need to select three UC campuses/include three UC Study Plans with your application Student Name: ID number (personnummer): I wish to study the following UC major/s (academic fields) during my stay at the UC campus: 1. 2. (optional) Area of
https://www.lunduniversity.lu.se/sites/www.lunduniversity.lu.se/files/2023-09/UC_study_plan_application_Fall_2021.pdf - 2026-07-07
