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Lactobacillus is a heterogeneous bacterial genus comprising at present 91 species. The high species number often makes classification and identification difficult, especially as the taxonomy to a high degree has been based on phenotypical traits. Members of the genus are of commercial importance, involved in a range of industrial products and applied as probiotics, “live microorganisms which when
In the studies presented in this thesis, hyperpolarized tracers have been used for the study of macroscopic flow and capillary perfusion with magnetic resonance imaging. The feasibility of performing vascular studies using echo-planar imaging (EPI) and hyperpolarized 129Xe was investigated using xenon dissolved in ethanol prior to injection into a flow phantom. It was concluded that hyperpolarized
Popular Abstract in Swedish Avhandlingen beskriver fonologin, morfologin och syntaxen för Lalo-språket, närmare bestämt som detta talas i Longjie landsortskommun i provinsen Yunnan i Kina. Lalo är ett språk som talas av ca 500 000 människor i sydvästra Kina. Språket tillhör burmesisk-yipho-språken, och har SOV-ordföljd, toner, fonationstyp, klassmärken m m. Avhandlingen är baserad på fältdata, iThe thesis is a descriptive reference grammar of the present-day Lalo language as spoken in Longjie township in Yunnan province of Southwestern China. It constitutes a presentation of empirical data collected during field work in Longjie township, and includes as survey of the phonology, morphology and syntax of the language. A word-list as well as text samples are appended to the thesis. Lalo is
Popular Abstract in Swedish Populärvetenskaplig sammanfattning Öroninflammtionen är en av våra vanligaste åkommor, och den drabbar framför allt små barn. Av alla bakteriella infektioner är det den som oftast för oss till läkare. Vanligen resulterar läkarbesöket i en kur med bakteriedödande läkemedel som penicillin. P.g.a den idag höga konsumtionen av penicillin och liknande medel, är risken påtagAcute otitis media (AOM) is the most common illness diagnosed during early childhood. One of the major etiologic agents is Haemophilus influenzae. Apart from AOM, this organism can cause a broad range of infectious diseases such as meningitis, epiglottitis, arthritis, and pneumonia. Despite the importance of H.influenzae, the mechanisms by which this heterogenous group of bacteria mediates the inf
Female moths emit sex pheromones to lure a mate. In this thesis I examined the transcriptomes of female moth pheromone glands in order to identify genes encoding proteins involved in pheromone production. Two cDNA-libraries were constructed from Agrotis segetum (Noctuidae) pheromone glands and the remaining body tissue, respectively. The libraries were sampled and sequenced. A total of 707 unigene
Popular Abstract in Swedish Den molekylära processen under vilken DNA-information förs över till RNA-information kallas transkription. Transkription styrs främst i samverkan med många speciella molekyler som kallas transkriptionsfaktorer. Zinkfinger proteiner är en av de vanligast förekommande klasserna av reglerande proteiner i eukaryota celler där de inverkar på en mängd av cellulära aktiviteterThe molecular process under which message in DNA is relayed onto RNA is called transcription, and it accomplished through involvement of so-called transcription factors. Zinc finger proteins are one of the most abundant classes of regulatory proteins in eukaryotic cells where they play central roles in a variety of cellular activities. A classical zinc finger is a small protein motif with a simple
Popular Abstract in Swedish Denna avhandling är uppbyggd kring fyra artiklar som berör reglering av gener i B-celler. B-cellerna är en viktig del av vårt immunförsvar, de sköter produktionen av antikroppar som hjälper till att skydda våra slemhinnor och vårt inre från sjukdomsframkallande bakterier och virus. Kroppens försvar mot sådana patogener består av flera delar, inklusive vår hud och våra sEach Ig V-region has its own upstream promoter and the promoter of a mature Ig gene is thereby selected during the V(D)J recombination process. Upon comparison, it is evident that only one transcription factor binding site, the octamer, is preserved within all promoters. The octamer motif and the binding Oct-proteins are crucial for Ig promoter function, but not sufficient for a high level of tran
The word “desertification” was introduced in 1949 by the French scientist Aubreville in his report “Climats, forêts et désertification de l´Afrique tropicale”. The concept, however, was discussed earlier by European and American scientists in terms of increased sand movements, desiccation, desert and Sahara encroachment and man made deserts. Desertification, at the beginning of last century, mea
Thirty-three Lactobacillus strains were tested as adjuncts in a cheese model system. Eighteen strains originated from cheese (nine Lactobacillus spp. and nine Lb. paracasei/casei) and 15 from human intestinal mucosa (11 Lb. rhamnosus; three Lb. paracasei; one Lb. plantarum). Model cheeses weighing 120 g were made of cheese grains from full-scale production of washed curd semi-hard cheese (Herrgard
Chromosome abnormalities have been reported in more than 46,000 benign and malignant neoplastic disorders, leading to the identification of numerous recurrent abnormalities. A substantial number of recurrent balanced aberrations (RBAs), in particular, reciprocal translocations, occur with remarkable specificity in association with clinical and tumor characteristics. This information has become inc
Bilateral clinical breast carcinoma has been reported to appear in up to approximately 10% of patients with breast carcinoma. Increasing diagnostic activity has raised figures of bilaterality, mainly due to detection of lesions of the in situ type. Knowledge of the natural history of carcinoma in situ is incomplete and clinical implications are uncertain. In the present study bilateral lesions wer
Human ECV304 cells respond reproducibly by tube formation to complex basement membrane matrices. Laminins are major glycoproteins of basement membranes. We therefore studied the ability of ECV304 cells to attach to defined laminin isoforms and to fibronectin, and identified the involved laminin receptors. The cells bound poorly to fibronectin, to some extent to laminin-1, whereas laminin-2/4 and -
Financial assurance is increasingly seen as a means to ensure orderly, clean and lasting closure of mines. Broadly interpreted, "closure" requires leaving viable ecosystems on mining lands that are compatible with a healthy environment and with human activities, that have low hazard, and that encompass measures to prevent ongoing pollution from the site in the long-term. Financial assurance encomp
OBJECTIVE: To evaluate the development of handicap in patients with rheumatoid arthritis (RA) followed 8 years from onset. METHODS: The study group consisted of 106 patients participating in a prospective early RA study. The mean duration of joint symptoms at inclusion was one year. The patients were assessed at least once annually. Disability was measured with the Health Assessment Questionnaire
1 A study of allozyme variation in vegetatively propagating populations of the rhizomatous sedge Carex bigelowii, revealed high levels of clonal diversity (genet diversity) within populations. The structure of allelic variation within the populations suggests that sexual reproduction has played a significant role in these C. bigelowii populations, despite present lack of seedling recruitment. The
A previously undescribed human member of the cystatin superfamily called cystatin F has been identified by expressed sequence tag sequencing in human cDNA libraries. A full-length cDNA clone was obtained from a library made from mRNA of CD34-depleted cord blood cells. The sequence of the cDNA contained an open reading frame encoding a putative 19-residue signal peptide and a mature protein of 126
BACKGROUND: This study focused on how cognitive ability, personality traits, self-rated psychiatric symptoms, and social functioning were related to the way in which patients with psychosis perceived supportive aspects of the ward atmosphere. METHODS: Patients at a psychiatric rehabilitation unit (PRU) in southern Sweden completed a ward atmosphere questionnaire (COPES), rated their psychiatric sy
Two quasi steady-state solute transport experiments were carried out in a loamy sand under field conditions. The flux was 40 mm/d in experiment I and 18.7 mm/d in experiment 2. Both water content (theta) and resident concentration (C-r) measurements were taken using 64 time domain reflectometry probes at depths ranging from 0.05 to 0.90 m. The C-r measurement was calibrated in situ for each probe
Abnormalities in nuclear morphology are frequently observed in malignant tissues but the mechanisms behind these phenomena are still poorly understood. In this study, the relation between abnormal nuclear shape and chromosomal instability was explored in short-term tumor cell cultures. Mitotically unstable ring and dicentric chromosomes were identified by fluorescence in situ hybridization at meta
Stored-product moths cause large economic damage in food-processing industries and storage facilities. Control of indoor pests is currently dealt with locally, and control strategies seldom include different mills or cooperative industries in joint efforts to reduce infestations. In colder climates where conditions hinder flight dispersal of stored-product moths, we hypothesize that human transpor
