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I Sverige drabbas omkring 300 barn av cancer varje år och majoriteten av dem är bara fyra-fem år gamla när de får sin diagnos. Omkring två tredjedelar av barncancerdiagnoserna utgörs av leukemier, lymfom och hjärntumörer, medan den sista tredjedelen är olika solida tumörformer som njurtumörer och nervvävnadstumörer i buken. Cancersjukvårdens utveckling under de senaste årtiondena har medfört en avPurpose: The purpose of this study was to evaluate the impact of including PET (Positron Emission Tomography) in the process of pediatric radiation therapy planning. The aim was to study the effect on target volumes and how this in turn affects the resulting treatment plans. This study also aims to compare the estimated risks of various long-term complications and how the use of PET influences the

This thesis studies the efforts made by society to achieve more efficient energy use in order to better utilise resources and lessen the stress on the environment. Despite the value to society promised by more efficient energy use, too few attempts are made at realising this value. One instrument available to governments in their efforts to stimulate efficiency schemes, is to encourage energy comp

Hotspot tracks (quasilinear chains of seamounts, ridges, and other volcanic structures) provide important records of plate motions, as well as mantle geodynamics, magma flux, and mantle source compositions. The Tristan-Gough-Walvis Ridge (TGW) hotspot track, extending from the active volcanic islands of Tristan da Cunha and Gough through a province of guyots and then along Walvis Ridge to the Eten

Ultrarelativistic heavy-ion collisions, which take place at particle accelerators like the BNL Relativistic Heavy Ion Collider (RHIC) and the CERN Large Hadron Collider (LHC), are known to produce a strongly-interacting, fluid-like state of matter referred to as the Quark-Gluon Plasma (QGP). Despite the medium’s short lifetime of approximately 10-23 s, its presence is known to influence particle p

Populärvetenskaplig sammanfattning: Planera dagsutflykten och upplev mer av Island. Island med sina aktiva vulkaner och stora glaciärer är ett populärt turistmål och antalet turister ökar år från år. Flertalet av de 350 000 utländska turister som årligen besöker Island anländer med flyg till huvudstaden Reykjavik. Från huvudstaden anordnas dagsutflykter genom en rad olika researrangörer. Man kan äIceland with its active volcanoes and big glaciers is a popular place for tourists and the number of tourists increases yearly. The majority of the 350 000 foreign tourists that visit Iceland each year arrive by plane to the capital city Reykjavik. Many different tour operators arrange day tours from the city. One can also plan day tours oneself and use a rental car. Increasing numbers of tourists

elwood is the main source of cooking and heating energy for households in rural sub-Saharan Africa. Unfortunately, most of these households use inefficient biomass cook stoves, leading to consumption of more fuel and exposure to indoor air pollutants and associate health problems which disproportionately affect women and children. However, adoption of cleaner biomass cook stoves has remained low w

Accurate precipitation data are crucial for hydrological modelling and rainwater runoff management. Precipitation variability exists through a wide range of spatial and temporal scales and cannot be captured well using sparse rain gauge networks. This limitation is further emphasised for urban and mountainous catchments, especially under global warming, causing an increased frequency of extreme ev

BACKGROUND: Vasopressin is widely used for vasopressor support in septic shock patients, but experimental evidence suggests that selective V1A agonists are superior. The initial pharmacodynamic effects, pharmacokinetics, and safety of selepressin, a novel V1A-selective vasopressin analogue, was examined in a phase IIa trial in septic shock patients.METHODS: This was a randomized, double-blind, pla

Rationale: Amyloid-β (Aβ) pathology is one of the earliest detectable brain changes in Alzheimer’s disease pathogenesis. In clinical practice, trained readers will visually categorise positron emission tomography (PET) scans as either Aβ positive or negative. However, adjunct quantitative analysis is becoming more widely available, where regulatory approved software can currently generate metrics

Allergic disease affects millions of individuals worldwide and leads to both impaired life quality of the affected individuals and large economic costs for the society. Allergen-specific antibodies of IgE type act as one of the key players in the disease, by activating effector cells upon binding of its allergen. Allergen-specific antibodies of other isotypes, such as IgG, can instead act protecti

Propionic acid (PA) is a naturally occurring short chain fatty acid produced by microbial fermentation of the indigestible foods in the intestine, having a positive effect on the gastrointestinal health. PA inhibits the growth of pathogenic bacteria and molds; hence it is widely used as preservative for food, feed and grains. It is also used as a component in several industrial products like polym

The human pathogen Streptococcus pyogenes causes substantial morbidity and mortality. It is unclear if antibodies developed after infections with this pathogen are opsonic and if they are strain specific or more broadly protective. Here, we quantified the opsonic-antibody response following invasive S. pyogenes infection. Four patients with S. pyogenes bacteremia between 2018 and 2020 at Skåne Uni

Importance: Reflex syncope is the major cause of transient loss of consciousness, which affects one-third of the population, but effective treatment for individuals with severe syncope is lacking. Better understanding of reflex syncope predisposition may offer new therapeutic solutions.Objectives: To determine the familial risk of syncope in first-, second-, and third-degree relatives of affected

En majoritet av människorna i den industrialiserade delen av världen använder Internet varje dag. Det sker ett pågående skifte från fysisk handel till e-handel, vilket innebär att Internet i benämningen handelsplats växer snabbt. Denna uppsats behandlar försäljning på Internet i kombination med den EU-rättsliga regleringen av vertikala avtal. Syftet med arbetet är att utreda de rättsliga konsekvenA majority of the people in the developed world use Internet on a daily basis. There is a shift from physical commerce to e-commerce, meaning that Internet as a market place is growing rapidly. This paper investigates online sales combined with the EU regulation regarding vertical agreements and its purpose is to investigate the legal consequences of online passive sales. In order to achieve the s

Bark beetle attacks have led to widespread tree disturbance and deaths in many parts of the world, and thereby also economic and biodiversity losses. Forest-rich Sweden has experienced periodic attacks, latest in 2018. There is a great interest in identifying the most important explanatory features behind bark beetle attacks and making spatial predictions on where attacks might happen. This could

Uppsatsen syftar att undersöka förlikningsavtal vid hantverkstjänster och småhusentreprenad samt undersöka felbestämmelserna i 9 – 14 §§ konsu-menttjänstlagen (1985:716) (KtjL) och jämföra bestämmelserna om fel för hantverkstjänster med specialbestämmelserna om småhusentreprenad i 51 – 61 §§ KtjL. Den traditionella rättsdogmatiska metoden har använts för att uppfylla syftet med arbetet samt ge svaThe purpose of the thesis is to study conciliation agreements within repair and remodeling activities and constructions considering family dwellings as well as research the regulations of faults in the consumers services act 9 – 14 §§ and compare the rules applied on repair and remodeling activities with the special rules applied on family dwellings found in the consumers services act 51 – 61 §§.

Jord- och skogsbruk utgör en viktig faktor för det svenska samhället; inte bara vad gäller sysselsättningar och exporter, utan även ur en historisk aspekt. Traditionellt har jord- och skogsmark vanligtvis gått i arv mellan generationer och med detta i beaktning har det således ställts upp stränga krav för när och under vilka omständigheter som juridiska personer får förvärva sådan mark. JordförvärAgriculture and forestry are important to Swedish society, not only in terms of employment and exports, but also from a historical perspective. Traditionally, agricultural and forestry land has usually been inherited between generations. Strict requirements have thus been set for when and under what circumstances legal persons may acquire such land. The Land Acquisition Act regulates the situation

År 2022 antogs en lagreform för att stärka brottsoffers ställning och minska skadeverkningarna av brott. Den nya lagstiftningen skulle bland annat utvidga rätten till kränkningsersättning och medföra kraftigt höjda ersättningsnivåer. Syftet med denna uppsats är att undersöka den rättsliga regleringen avseende kränkningsersättning och de senaste lagändringar som skett för att höja ersättningsnivåIn 2022, a law reform was passed to strengthen the position of crime victims and reduce the harmful effects of crime. The new legislation intended, among other things, to expand the right to compensation for violations and bring about distinct increases in compensation levels. The purpose of this essay is to examine the law relating to compensation for violations and the most recent amendments th

This Master thesis explores the EU law requirements for the taxation of the provision of cross-border services by the source state. As often the field of direct taxation, this is a delicate area where tension exists between the tax sovereignty of the Member States and the EU’s aim of the realization of an internal market. The CJEU has ruled several times on different tax legislation of different M

Titel: Placering av europeiskt distributionscentrum för att minska LUL-transporter för företag inom industrin för lagrade alkoholhaltiga drycker Författare: Josefin Berntson, Cecilia Flink Handledare: Sebastian Pashaei, Avdelningen för industriell ekonomi och logistik, Lunds Tekniska Högskola, Lunds universitet. Problembeskrivning: Den ökade efterfrågan av distribution, som ett resultat av den Title: Allocation of a European Distribution Center to Minimize LUL Shipments for Companies within the Aged Alcoholic Beverage Industry Authors: Josefin Berntson, Cecilia Flink Supervisor: Sebastian Pashaei, Department of Industrial Management and Logistics, Faculty of Engineering, Lund University Problem description: The increased demand for distribution as a result of the globalization has in