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Shortcomings of current techniques used for the intracerebral transplantation of ventral mesencephalic dopamine neurons include low graft survival, high variability, considerable implantation trauma and suboptimal graft integration. In order to overcome these limitations, we have adopted a microtransplantation approach which allows precise and reproducible implantation of ventral mesencephalon cel
Avian Influenza Viruses (AIVs) infect many mammals, including humans1. These AIVs are diverse in their natural hosts, harboring almost all possible viral subtypes2. Human pandemics of flu originally stem from AIVs3. Many fatal human cases during the H5N1 outbreaks in recent years were reported. Lately, a new AIV related strain swept through the human population, causing the 'swine flu epidemic'4.
Objective: To compare mortality and costs of health and social care between participants with access to care based on Comprehensive Geriatric Assessment (CGA) in an out-patient care setting with a control group receiving usual care only. The comparison was done 36 months after inclusion. Methods: Randomized controlled trial. Inclusion criteria: community-dwelling, aged ≥75 years, ≥3 hospitalisatio
Background: Calcitonin gene-related peptide (CGRP) is one of the most potent endogenous vasodilators identified to date. The present study elucidates the differential interaction of CGRP, its receptor and the effect of the CGRP-receptor antagonist telcagepant on intracellular Ca2+ -levels and tension in rat middle cerebral arteries (MCA) by pressurized arteriography, FURA-2/wire myography and immu
Elephant Moraine (EET) 96029 is a CM carbonaceous chondrite regolith breccia with evidence for unusually mild aqueous alteration, a later phase of heating and terrestrial weathering. The presence of phyllosilicates and carbonates within chondrules and the fine-grained matrix indicates that this meteorite was aqueously altered in its parent body. Features showing that water-mediated processing was
The clinical pharmacology of desmopressin and a new vasopressin analogue (F992) was investigated in healthy human subjects. The common procedure of overhydration of healthy volunteers when studying the antidiuretic effect of a drug, may affect the pharmacokinetics, in particular the volumes of distribution. Hence, the estimated parameters may not be relevant to euhydrated patients. F992 was found
The Internet is a huge world-wide packet switching network comprised of more than 13,000 distinct subnetworks, referred to as Autonomous Systems (ASs) . They all rely on the Internet Protocol (IP) for transport of packets across the network. And most of them use shortest path routing protocols , such as OSPF or IS-IS, to control the routing of IP packets within an AS. The idea of the routing is ex
Over the years consumer packaging has become increasingly important as a value-adding element, since packages shape the consumer’s experience with the product during use, as well as accelerate the purchase decision. From a prod-uct/service system perspective, the strategic benefits of viewing packaging as a central value carrier are evident. To consumers, the product and its packaging are often pe
Lignocellulose constitutes a vast renewable resource for the production of, for example, paper and bioethanol. The potential of using laccase and oxalate-degrading enzymes in novel applications for the processing of lignocellulose was investigated in this work. Laccase cDNAs from the white-rot fungus Trametes versicolor were characterised and expressed in Saccharomyces cerevisiae and Pichia pastor
Summary form only given. The advanced resource connector (ARC), or the NorduGrid middleware, is an open source software solution enabling production quality computational and data grids. Since the first release (May 2002), the middleware is deployed and being used in production environments. Emphasis is put on scalability, stability, reliability and performance of the middleware. A growing number
A method for calculating circulation indices and weather types following the Lamb classification is applied to southern Scandinavia. The main objective is to test the ability of the method to describe the atmospheric circulation over the area, and to evaluate the extent to which the pressure patterns determine local precipitation and temperature in Scania, southernmost Sweden. The weather type cla
Popular Abstract in Swedish Företag konkurrerar med varandra i strävan efter att nå den högsta lönsamheten. En mängd frågor måste tas under övervägande för att nå ett sådant mål - beslut angående produkter, marknader, kunder och, ej att förglömma, organisation måste fattas. När det gäller organisation kan ett företag välja mellan att själv göra en särskild produkt och att köpa den från ett annat fFirms compete with each other to earn the highest profit. A wide range of issues needs to be considered in order to do so – decisions about products, markets, customers and, not to forget, organisation have to be made. Concerning organisation, a business firm can choose to make a particular thing (a good or service) by itself or to buy it from someone else. The decision determines the way in which
Popular Abstract in Swedish Ansträngningen att framställa nya förnyelsebara drivmedel har under de senaste årtionden ökat markant. Anledningarna har varit flera, dels oron för klimatpåverkan vid användningen av fossila bränslen, dels från ett nationellt energisäkerhetsperspektiv då lokal produktion skulle kunna stabilisera tillgången. Bioetanol är ett av de största biobränslena i världen och produFuel ethanol from lignocellulosic biomass has the potential to provide a sustainable replacement for traditional oil-based fuels. This dissertation assesses the processing of three different lignocellulosic materials – spruce, wheat straw and giant reed – at industrially relevant solid loadings. The work is divided into two main parts. The first part deals with the degradation of biomass to sugars
Popular Abstract in Swedish Min avhandling handlar om vilken roll fiskyngel har i samspelet mellan olika organismer i våra sjöar, såsom i samspelet mellan rovfiskar, djurplanktonätande fiskar, djurplankton och alger. Fisklarver och fiskyngel förekommer i stora mängder i våra sjöar under sommaren. Varje vår/sommar kläcks nya kullar av bl.a. abborre och mörtlarver, vilka äter (prederar på) små djur
Popular Abstract in Swedish Antalet fall av tuberkulos (TB) har ökat parallellt med den globala spridningen av hiv. TB orsakar omkring 1.5 miljoner dödsfall årligen, och är den vanligaste dödsorsaken hos hivpositiva. Under det senaste årtiondet har tillgången till livräddande behandling mot hiv (antiretroviral terapi; ART) ökat kraftigt i låginkomsländer – särskilt i Afrika söder om Sahara. I dessHIV and tuberculosis (TB) remain the two most common infectious causes of death worldwide. During the recent decade antiretroviral treatment (ART) has become available for millions of people living with HIV (PLHIV) globally; yet more than half of PLHIV have not yet initiated ART. In order to achieve universal access, further decentralization of care is needed. This is a major challenge to health s
Aim: To evaluate the efficacy of two different Swedish screening procedures for early detection of congenital cataracts in comparison with no screening. Methods: Children born between January 1992 and December 1998 in Swedish regions with an established eye-screening routine procedure, diagnosed with congenital cataract, and operated on before 1 y of age, were included in a retrospective study. Ag
The overall aim of this work was to study knee function movement pattern and knee osteoarthritis in males 14-16 years after anterior cruciate ligament (ACL) injury. In the first study, 154 male subjects with a 14-year-old ACL injury were investigated. Self-reported knee function and radiographic signs of osteoarthritis were assessed. Most of the subjects (122/154) underwent knee radiographs, 78% o
Popular Abstract in Swedish Avhandlingen studerar den svenska jordbruksomvandlingen under 1800-talet. Syftet är dels att analysera böndernas roll i jordbruksomvandlingen, dels att identifiera de egenskaper som de ledande bönderna, de agrara entreprenörerna, hade. Detta görs genom att studera ansökningar om skifte och kreditmarknadens utnyttjande i tre skånska socknar, Brösarp, Saxtorp och V. KarabThis study deals with the agricultural transformation in 19th century Sweden. The aims are: firstly, to analyse the peasants' role as entrepreneurs in the transformation of agriculture, and secondly, to identify the distinctive characteristics of the agrarian entrepreneurs by studying particular aspects of entrepreneurial dealings during the agricultural transformation in Scania between 1800 and 1
Aims and objectives. The aim of this study was to describe characteristics in burn injuries in children (zero to six years old), consulting primary care and hospital-based care in Malmo, Sweden. Burn-injured children consulting the University Hospital or the 21 Health Centres, during year 1998 and year 2002, were included. Background. Epidemiological studies of burns in children have mostly been h
