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Exposure to aerosol nanoparticles has always been present in the evolution of humans, and thus has the human body developed ways of dealing with particles that enters the body. However with the emerging nanotech industry, new types of nanoparticles are being produced and used. Many of these particles have properties never seen before and this rise concern about how exposure to them might cause unw

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Popular Abstract in Swedish Salmonella infektion drabbar ca 16 miljoner människor i världen per år. Salmonella sprids genom mat och vatten och fšrekommer främst i länder där god hygien är ett problem. Beroende på vilken typ av Salmonella som man infekteras av, kan man drabbas av magsjuka eller en allvarlig systemisk infektion som i värsta fall kan leda till döden (tyfoid feber). Salmonella tar sigThe immune system has several strategies to combat infections. The present study investigates various aspects of the interaction between Gram negative bacteria, particularly Salmonella, and antigen presenting cells (APC). Salmonella is an intracellular bacterium infecting mice and man. Salmonella typhimurium infection in mice is a frequently used model for studying systemic Salmonella infection. O

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In many European universities, English is today used as a medium of instruction. One of the reasons is that it is believed that using English as a medium of instruction (EMI) can develop students’ subject-specific knowledge of English. This knowledge is seen as an asset in the workplace and often presented as providing a competitive advantage supporting professional success. The design of many edu

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Prompt D meson and non-prompt J/psi yields are studied as a function of the multiplicity of charged particles produced in inelastic proton-proton collisions at a centre-of-mass energy of root s = 7 TeV. The results are reported as a ratio between yields in a given multiplicity interval normalised to the multiplicity-integrated ones (relative yields). They are shown as a function of the multiplicit

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During the stress response adrenal medullary chromaffin cells release catecholamines to the bloodstream. Voltage-activated calcium channels present in the cell membrane play a crucial role in this process. Although the electrophysiological and pharmacological properties of chromaffin cell calcium channels have been studied in detail, the molecular composition of these channels has not been defined

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We compared the influence of the microbial community composition and the environmental conditions for the functioning - microbial growth and respiration - and trait distribution - bacterial pH tolerance - of soil microorganisms across a pH gradient. Sterilised soil microcosms, including pH 4.1, 5.2, 6.7 and 8.3, with added plant litter were inoculated with unsterilized soil in a factorial design a

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Numerous auto-scaling strategies have been proposed in the past few years for improving various Quality of Service (QoS) indicators of cloud applications, for example, response time and throughput, by adapting the amount of resources assigned to the application to meet the workload demand. However, the evaluation of a proposed auto-scaler is usually achieved through experiments under specific cond

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Rabbit α1-microglobulin was purified from the urine of sodium-chromate-treated animals by the use of gel chromatography on Sephadex G-100 affinity chromatography on concanavalin-A - Sepharose and ion-exchange chromatography on DEAE-Sephadex. Rabbit α1-microglobulin had a molecular mass of 25.6 kDa on SDS/polyacrylamide gel electrophoresis. α1-microglobulin has previously been purified from the uri

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The purpose of this contribution is to present a survey of the recent developments in constructing composite science and technology (S&T) indicators on a national level as well as new evidence of the variability of such S&T indicators which opens the gateway to "country-tuning". It has become standard practice to combine several indicators for science, technology, and innovation to form co

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Altered sensory processing has been linked to symptoms of obsessive-compulsive disorder (OCD) and anxiety disorders (ADs) in youth, but few studies have examined sensory processing in clinical samples and no study has analyzed self-report data from youth meeting diagnostic criteria for OCD or ADs. This study included 86 youth with OCD, 82 youth with ADs, and 46 youth without psychiatric disorders.

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Background: The global struggle against antibiotic resistance requires antimicrobial stewardship (AMS). Massive open online courses (MOOCs) offer health professionals unprecedented access to high-quality instructional material on AMS; the question is how apprehensible it is to non-native English speakers. Furthermore, to better understand how education interventions promote change towards rational

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Objective. To evaluate the influence of preoperative abstinence on postoperative outcome in alcohol misusers with no symptoms who were drinking the equivalent of at least 60 g ethanol/day. Design. Randomised controlled trial. Setting. Copenhagen, Denmark. Subjects. 42 alcoholic patients without liver disease admitted for elective colorectal surgery. Interventions. Withdrawal from alcohol consumpti

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Acute Respiratory Distress Syndrome is one of the more common fatal complications in COVID-19, characterized by a highly aberrant inflammatory response. Pre-clinical models to study the effect of cell therapy and anti-inflammatory treatments have not comprehensively reproduced the disease due to its high complexity. This work presents a novel physiomimetic in vitro model for Acute Respiratory Di

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Flip-flop processes due to magnetic dipole-dipole interaction between neighboring ions in crystals doped by rare-earth ions are one of the mechanisms of relaxation between hyperfine levels. Modeling of this mechanism has so far been macroscopic, characterized by an average rate describing the relaxation of all ions. Here, however, we present a microscopic model of flip-flop interactions between in

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Green infrastructure (GI) is increasingly used in policymaking to promote biodiversity and enhance ecosystem services through the protection, creation, restoration and connection of natural and man-made green areas. The EU Commission adopted in 2013, the concept as a strategy. When member states apply the policy, it is translated into specific bureaucratic and political systems, creating different

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One of the biggest challenges in urban densifications is securing adequate daylight access. This study examines the potential of using semantic 3D city models as input to daylight simulations. It is focusing on investigating input data requirements to these simulations from a geodata, 3D city model specification and measuring guideline perspective. To achieve this, geodata simulation input require

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Minor structural changes on the surface of proteins can have tremendous impact on their biological properties. When producing therapeutic proteins it is therefore important to verify that the generated protein is the desired one. Small variations such as glycosylations or amino acid substitutions can mean the difference between a functional, defective or even toxic product. This thesis describes

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Carriers of BRCA1 germline pathogenic variants are at substantially higher risk of developing breast and ovarian cancer than the general population. Accurate identification of at-risk individuals is crucial for risk stratification and the implementation of targeted preventive and therapeutic interventions. Despite significant progress in variant classification efforts, a sizable portion of reporte

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Climate change is predicted to cause milder winters and thus exacerbate soil freeze–thaw perturbations in the subarctic, recasting the environmental challenges that soil microorganisms need to endure. Historical exposure to environmental stressors can facilitate the microbial resilience to new cycles of that same stress. However, whether and how such microbial memory or stress legacy can modulate