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Path diagrams : configurational descriptions from GIS data, an algorithm and its implications

This paper proposes and explains a type of diagrams which share some of the characteristics distinctive of axial maps, while also differing substantially in some other aspects. A main discussion in Space Syntax is the capacity of different diagrammatic representations to describe relevant morphological characteristics of space: convex maps or visibility graphs at the scale of buildings; axial maps

Psychosocial Determinants for Self-Reported Health Status in Hemodialysis Patients : A Cohort Analysis of the CONVINCE Randomized Trial

Background: We investigated whether psychosocial determinants self-efficacy and social support are associated with Health-Related Quality of Life in hemodialysis patients enrolled in the CONVINCE trial. Methods: We used baseline data from the cohort of patients involved in the CONVINCE randomized trial of hemodiafiltration versus hemodialysis. Measures included age, gender, relationship status, ch

Social Bodies: Family and community influences on height and weight, Southern Sweden 1818–1968

This dissertation consists of an introduction, four research papers and one paper describing the data I collected for the studies and how I conducted the study. I collected information on men from conscript inspection lists and linked this to a sample of men in the Scanian Economic Demographic Database (SEDD) born between 1797 and 1950. The four research papers analyze influences on height and wei

Synthesis, conformational analysis and biological activity of xylopyranosyl sulfur-containing glycosides : dependence of sulfur atom configuration

Proteoglycans (PGs) consist of a core protein with covalently bound glycosaminoglycan (GAG) chains that are linked via a tetrasaccharide. PGs are important macromolecules that are involved in biological processes such as cell growth and differentiation. A key enzyme in the biosynthesis of PG GAG chains is β-1,4-galactosyltransferase 7 (β4GalT7) that catalyzes the transfer of galactose to a xylose

Women experiencing the second stage of labour for the first time : A qualitative free-text analysis within the Oneplus trial

Title: Women experiencing the second stage of labour for the first time: a qualitative free-text analysis within the Oneplus trial. Background: The second stage of labour is the time from full cervical dilation to the birth of the baby. The risks to the woman and the baby are increased during this stage, leading to intensified midwifery care. A positive birth experience is a significant goal of in

ESTRO/EANO recommendation on reirradiation of glioblastoma

Background and Purpose: Although reirradiation of glioblastoma has a long history of clinical practice, guidance on how to perform it in the context of recent technological advances, modern imaging modalities or systemic therapy is scarce. This joint ESTRO/EANO guideline aims to collect the existing evidence to produce recommendations for safe reirradiation of glioblastoma. Methods: The basis of t

Reliability and validity of motion analysis in children treated for congenital clubfoot according to the Clubfoot Assessment Protocol (CAP) using inexperienced assessors

Background. The Clubfoot Assessment Protocol (CAP) was developed for follow-up of children treated for clubfoot. The objective of this study was to analyze reliability and validity of the six items used in the domain CAPMotion Quality using inexperienced assessors. Findings. Four raters (two paediatric orthopaedic surgeons, two senior physiotherapists) used the CAP scores to analyze, on two differ

Basal forebrain grafts in the hippocampus and neocortex : regulation of acetylcholine release

The regulation of acetylcholine (ACh) release from cholinergic neurons transplanted to the hippocampus or neocortex was studied by microdialysis in awake rats. Fetal basal forebrain tissue was implanted as a cell suspension or solid graft into the fimbria-fornix-lesioned hippocampus, or as a cell suspension into the frontal cortex after excitotoxic lesion of the nucleus basalis. Several months aft

CP-North: living life in the Nordic countries? : A retrospective register research protocol on individuals with cerebral palsy and their parents living in Sweden, Norway, Denmark, Finland and Iceland

INTRODUCTION: Cerebral palsy (CP) is one of the most common neurodevelopmental disabilities. Yet, most individuals with CP are adults. How individuals with CP fare in terms of health, quality of life (QoL), education, employment and income is largely unknown. Further, little is known about the effects of having a child with CP on the parents. The Nordic countries are known for their strong welfare

Geographical proximity and the transmission of drug abuse among siblings : Evaluating a contagion model in a Swedish National Sample

AimsCan drug abuse (DA) be transmitted psychologically between adult siblings consistent with a social contagion model?MethodsWe followed Swedish sibling pairs born in 1932-1990 until one of them, sibling1 (S1), had a first DA registration. We then examined, using Cox regression, the hazard rate for a first registration for DA in sibling2 (S2) within 3 years of a first DA registration in S1 as a f

Reducing the Uncertainty on the Hubble Constant up to 35% with an Improved Statistical Analysis : Different Best-fit Likelihoods for Type Ia Supernovae, Baryon Acoustic Oscillations, Quasars, and Gamma-Ray Bursts

Cosmological models and their parameters are widely debated, especially about whether the current discrepancy between the values of the Hubble constant, H 0, obtained by Type Ia supernovae (SNe Ia) and the Planck data from the cosmic microwave background radiation could be alleviated when alternative cosmological models are considered. Thus, combining high-redshift probes, such as gamma-ray bursts

Trends in cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for the treatment of synchronous peritoneal carcinomatosis of colorectal origin in the Netherlands

BACKGROUND: Population-based data on the percentage of colorectal cancer (CRC) patients with synchronous peritoneal carcinomatosis (PC) being treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are currently lacking. The current population-based study describes trends in the use of CRS-HIPEC in the Netherlands, one of the first countries where CRS and HIP

Improving neural network classification of indigenous forest in New Zealand with phenological features

Accurate and up-to-date land cover maps inform and support effective management and policy decisions. Describing phenological changes in spectral response using time-series data may help to distinguish vegetation types, thereby allowing for more specificity within vegetation classification. In this research, we test this by classifying indigenous forest vegetation in New Zealand, using PlanetScope

Tailored fluorouracil, epirubicin, and cyclophosphamide compared with marrow-supported high-dose chemotherapy as adjuvant treatment for high-risk breast cancer : a randomised trial

BACKGROUND: Chemotherapy drug distribution varies greatly among individual patients. Therefore, we developed an individualised fluorouracil, epirubicin, cyclophosphamide (FEC) regimen to improve outcomes in patients with high-risk early breast cancer. We then did a randomised trial to compare this individually tailored FEC regimen with conventional adjuvant chemotherapy followed by consolidation w

3D technology of Sony Bloggie has no advantage in decision-making of tennis serve direction : A randomized placebo-controlled study

This study aimed at exploring whether 3D technology enhances tennis decision-making under the conceptual framework of human performance model. A 3 (skill-level: varsity, club, recreational) × 3 (experimental condition: placebo, weak 3D [W3D], strong 3D [S3D]) between-participant design was used. Allocated to experimental conditions by a skill-level stratified randomization, 105 tennis players judg

Synthesis of glycophospholipid conjugates with mono- and disaccharides by enzymatic transphosphatidylation

Phospholipids, PLs, are interesting and highly abundant amphiphilic molecules, which self-assemble into 3D nanostructures that have big interest as formulation excipients in, for example, pharma industry. However, the structures that are formed by naturally occurring PLs usually suffer from rigidity problems, and the nanostructures have to be modified in various ways for improved stability. One su

Response and resilience to drought in northern forests revealed by Sentinel-2

Enhancing forest drought resilience is important for preserving ecosystem services in the face of climate change, but operational management methods for boreal forests aiming to preserve ecosystem services under drought are still largely missing. This study explores the use of satellite remote sensing to monitor vegetation stress phases related to drought progression and to quantify both short- an

Resource allocation and the burden of co-morbidities among patients diagnosed with chronic obstructive pulmonary disease : an observational cohort study from Danish general practice

BACKGROUND: Chronic obstructive pulmonary disease is a leading cause of mortality, and associated with increased healthcare utilization and healthcare expenditure. In several countries, morbidity-based systems have changed the way resources are allocated in general practice. In primary care, fee-for-services tariffs are often based on political negotiation rather than costing systems. The potentia

Ett brännglas för tidens strålar : striden om Torgny Segerstedts docentur 1903

Popular Abstract in Swedish Torgny Segerstedt, den kände chefredaktören för Göteborgs Handels- och Sjöfartstidning, hade utkämpat strider före nazismens tid. Som ung kallades han till docent till Lund på en underkänd avhandling. Disputationen hade ägt rum i maj 1903 vid den teologiska fakulteten i Uppsala. Efter underkännandet beslöt alltså den teologiska fakulteten i Lund att kalla Segerstedt tilOn 1st September 1903, the Faculty of Theology at the University of Lund took the decision to appoint Torgny Segerstedt as a senior lecturer in spite of his failed doctoral dissertation. The public defence of his thesis had taken place on 28th May in the same year before the Faculty of Theology at Uppsala. It was thus after his failure that the Faculty at Lund nevertheless decided to invite him to

Is the Intramedullary Skeletal Kinetic Distractor a Safe Measure for Bone Lengthening? A Systematic Review

The intramedullary skeletal kinetic distractor (ISKD) is one of the relatively recent methods developed to overcome the complications of conventional bone lengthening methods, such as external fixators. These complications include pain, muscle transfixation, pin-tract infection, reduced joint motion, and prolonged fixation time. However, ISKD-specific complications such as uncontrollable lengtheni