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PURPOSE: Whether coffee modulates response to endocrine therapy in breast cancer patients is currently unknown. The CYP1A2 and CYP2C8 enzymes contribute to tamoxifen and caffeine metabolism. The purpose was to investigate the impact of coffee consumption on tumor characteristics and risk for early events in relation to breast cancer treatment and CYP1A2 and CYP2C8 genotypes. METHODS: Questionnaire
Today we live in an interconnected world. Through globalization and the development of information technology one can say that, today everyone is our neighbour. The result of our actions can easily spread and affect people on the other side of the world within seconds. Meanwhile, Third World countries are developing into stable economies and Western European corporations are expanding like never
The European Union boasts free movement of workers as one of its fundamental freedoms for all citizens. However, this freedom does not exist free from controversy or challenging issues. Professional workers raise unique problems when considering the exercise of this freedom. Member States in which the professionals wish to practice are reasonably concerned with assuring that the professionals prac
In this paper, a model inspired by Grand Unification principles featuring three generations of vector-like fermions, new Higgs doublets and a rich neutrino sector at the low scale is presented. Using the state-of-the-art Deep Learning techniques we perform the first phenomenological analysis of this model focusing on the study of new charged vector-like leptons (VLLs) and their possible signatures
Jordan has one of the lowest available water supplies in the world; meanwhile, Jordan has seen a large increase in population and refugee’s fluxes, leading to an increase in water demand. To address this unprecedented water scarcity, Jordan’s water must be used where its social and economic value is highest. Jordan must treat and reuse virtually every drop of water. With using brackish water (i.e,
The objective of this study was to assess erysipelas incidence before and after liposuction treatment for patients suffering from post-mastectomy lymphedema. A prospective cohort study of 130 patients at Skåne University Hospital in Malmö, Sweden with postmastectomy arm lymphedema, who had poor outcomes from prior conservative treatment and clinical signs of subcutaneous adipose tissue hypertrophy
Over a 15-year period, mobile phones have evolved from providing one single feature - the mobile voice call - to multi-featured multi-media communication and entertainment devices. Customer value has been added through successive integration of features previously conveyed by dedicated devices, as clock, timer, camera, media player, radio, etc. This continued integration strategy now poses several
This thesis is based on the assumption that the challenge of waste management needs to be addressed within the sustainability framework where society takes part in the solution. People’s beliefs, attitudes and values are what, ultimately, make people behave the way they do. Therefore this thesis intends to study a potential way of changing these worldviews towards more sustainable ones by utilizin
Allt sedan Öresundsbron öppnades år 2000 har både pendlingen över landsgränserna och integrationen i Öresundsregionen gått stadigt framåt. Det pendlas dagligen fram och tillbaka från bostaden i det ena landet till arbetet i det andra, framför allt är pendling över landsgränsen från bostaden i Sverige till arbetet i Danmark omfattande. Det finns alltid en risk för att en inkomsttagare blir dubbel
The purpose of this graduate thesis is to discuss the concept of democracy as conceived of by Alf Ross in his book ''Why democracy?, one of the most important works on democracy that appeared in the 20th century. Further, the thesis aims to establish whether or not Ross' views, seen against the background of modern Swedish democracy, might still be of interest in our days. According to
In the Swedish corporate income taxation, one of the most controversial fields is that withdrawal taxation, dividend taxation of the company owner, and the question of the assignee's acquisition cost when assets are sold below market value. The reason for the interest of that area is that selling assets below market value is a very common way of restructing company groups in accordance with th
Are there such things as moral, rights and an inner sense of justice? Do they origin from God or are they something given by nature? If there are such things, should they be a part of the legal system? This essay has drawn its inspiration from this kind of thoughts and how they have been handled through history. The structure of the essay is two-folded. Part one is a historical review of the eme
The thesis examines integration policy in Denmark in close linkage with the categories ―national identity‖, ―democracy‖ and ―welfare‖. The research interest is based on the assumption that all enumerated categories participate in framing integration policy and can be considered key factors in the analysis of the case of Denmark. ―National Identity‖ is presented in the theoretical discussion throug
Med röntgenstrålning går det i dagsläget att avbilda kroppens inre anatomi i antingen två eller tre dimensioner. Vid en vanlig slätröntgenundersökning (2D) tas en så kallad projektionsbild från en eller två vinklar, framifrån/bakifrån och från sidan. Detta genererar en tvådimensionell bild där alla (anatomiska) strukturer mellan röntgenröret och filmen överlagras, d.v.s. de går inte att separera fDuring the last century several attempts have been made to overcome the fundamental problem of X-ray imaging, i.e. that anatomical information existing in 3-dimensions has to be represented on a 2-dimensional radiograph. In this thesis, digital tomosynthesis, a rened version of conventional tomography, has been investigated. Digital tomosynthesisenables retrospective reconstruction of an arbitrary
Den Eurasiska shelfen var under Weichsel istiden täckt av inlandsisar centrerade i Barents och Kara Havet. Kanin Halvön i nordvästra Ryssland upptar en nyckelposition för att registrera de shelfbaserade isarnas passage över till fastlandet. De vidsträckta kvartära blottningarna längs dess nordkust erbjuder en unik möjlighet att studera istäckens fluktuationer och dynamiska beteende. Denna artikeDuring the Weichselian glaciation, ice sheets centred in the Barents and Kara Seas occupied the Eurasian shelf, although their nature and extent have been debated. In NW Russia the Kanin Peninsula occupies a key position for recording the passage of shelf based ice sheets onto the mainland. The extensive Quaternary exposures along its northern coast offer a unique possibility to study ice sheet fl
Is it Allowed to be Kind as a Professional? – A Study about Linguistic Boundary Work in Social Work Based on the Concept Kind Author: Tilde Olsson Title: Is it Allowed to be Kind as a Professional? – A Study about Linguistic Boundary Work in Social Work Based on the Concept Kind.[Translated title] Supervisor: Stig Linde Assessor: Staffan Blomberg The aim of this study was to examine variations of
Background: Arthropod eyes have diversified during evolution to serve multiple needs, such as finding mates, hunting prey and navigating in complex surroundings under varying light conditions. This diversity is reflected in the optical apparatus, photoreceptors and neural circuits that underpin vision. Yet our ability to genetically manipulate the visual system to investigate its function is large
Background: In the phase 3 TITAN study, the addition of apalutamide to androgen deprivation therapy (ADT) significantly improved the primary endpoints of overall survival and radiographic progression-free survival in patients with metastatic castration-sensitive prostate cancer. We aimed to assess health-related quality of life (HRQOL) in TITAN, including pain and fatigue. Methods: In this randomi
Background: Demographic changes combined with costly technological progress put a financial strain on the healthcare sector in the industrialized world. Hence, there is a constant need to develop new cost-effective treatment procedures in order to optimize the use of available resources. As a response, the concept of a Mobile Geriatric Team (MGT) has emerged not only nationally but also internatio
Background: North Sea Progressive Myoclonus Epilepsy is a rare and severe disorder caused by mutations in the GOSR2 gene. It is clinically characterized by progressive myoclonus, seizures, early-onset ataxia and areflexia. As in other progressive myoclonus epilepsies, the efficacy of antiepileptic drugs is disappointingly limited in North Sea Progressive Myoclonus Epilepsy. The ketogenic diet and
