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Large clinical studies describing the typical clinical presentation of diabetic foot ulcers are limited and most studies were performed in single centres with the possibility of selection of specific subgroups. The aim of this study was to investigate the characteristics of diabetic patients with a foot ulcer in 14 European hospitals in ten countries. The study population included 1,229 consecutiv
Calbindin D28k (calbindin) is a member of the calmodulin superfamily of Ca2+ -binding proteins. An intracellular target of calbindin was discovered using bacteriophage display. Human recombinant calbindin was immobilized on magnetic beads and used in affinity purification of phage-displayed peptides from a random 12-mer peptide library. One sequence, SYSSIAKYPSHS, was strongly selected both in the
Estimating the rate of soil carbon sequestration in degraded semiarid agroecosystems is of great interest due to the beneficial effects on soil properties, soil fertility, and the potential atmospheric CO2 mitigation. One of several applied methodologies, biogeochemical modeling, offers possibilities to distribute estimates of soil organic carbon (SOC) over regions, estimate the effects of changes
It is likely that everyone will, at some time, suffer from a problem related to the musculoskeletal system, ranging from a very common problem such as osteoarthritis or back pain to severely disabling limb trauma or rheumatoid arthritis. Many musculoskeletal problems are chronic conditions. The most common symptoms are pain and disability, with an impact not only on individuals’ quality of life bu
Popular Abstract in Swedish "Tanken i rörelse" handlar dels om hur tanken sätts i rörelse av brus och dels om hur detta brus kan användas av hjärnan för att fånga upp visuell rörelse. Ofta betraktas brus som en störning, men detta arbete försöker visa att brus kan ha en viktig funktion i tankeprocessen. Arbetet vill visa hur våra tankar växer fram ur det bakgrundsbrus som alltid finns i hjärnan i The brain is not silent. Even in the absence of stimuli are the neurons activated every now and then in what is called "spontaneous" or "background activity" which provides a noisy background to the operation of the brain. This work shows how this noise can be utilized in the cognitive process. That is, rather than being treated as a nuisance, noise is given a functional role in the brain´s activi
Ambient solar radiation effects on Phragmites australis leaf and culm litter were investigated in a shallow and eutrophic south Swedish lake littoral. Leaf and culm litter was exposed to natural sunlight in the lake at a water depth of a few centimeters. For the leaf litter, an additional subset of the experiment was exposed to solar radiation in the air, to evaluate effects of the solar radiation
The adsorption of the dicarboxylates o-phthalate, maleate, fumarate, malonate, and oxalate (representing ligands with the general composition -O2C-C-n-CO2; n = 0, 1, or 2) on gibbsite were studied by means of quantitative batch adsorption experiments and attenuated total reflectance Fourier. transform infrared (ATR-FTIR) spectroscopy. The interpretations of ATR-FTIR spectra were aided by compariso
The dissertation is a case study, the topic of which was a participant-oriented research project in which a development programme for support to parents and care of young people was to be implemented in the organization and the concrete social work was developed and changed through researcher-supported intervention. The project was part of a large-scale effort for change and development carried ou
AIM: To assess the prognostic value of repetitive serum samples of neuron specific enolase (NSE) and S-100B in cardiac arrest patients treated with hypothermia. METHODS: In a three-centre study, comatose patients after cardiac arrest were treated with hypothermia at 33 degrees C for 24h, regardless of cause or the initial rhythm. Serum samples were collected at 2, 24, 48 and 72h after the arrest a
Single nucleotide polymorphism (SNP) arrays are increasingly being used in clinical routine for genetic analysis of pediatric B-cell precursor acute lymphoblastic leukemias (BCP ALL). Because constitutional DNA is not readily available as a control at the time of diagnosis, it is important to be able to distinguish between acquired and constitutional aberrations in a diagnostic setting. In the pre
The aim of this study was to investigate the diffusion time dependence of signal-versus-b curves obtained from diffusion-weighted magnetic resonance imaging (DW-MRI) of sub-acute ischaemic lesions in stroke patients. In this case series study, 16 patients with sub-acute ischaemic stroke were examined with DW-MRI using two different diffusion times (60 and 260 ms). Nine of these patients showed suf
The presence of introduced brown trout (Salmo trutta) on the distribution of native crayfish (Paranephrops planifrons), native galaxiid fishes (Galaxias spp.) and invertebrate fauna was investigated in 18 West Coast New Zealand streams (8 with trout and 10 without trout) differing in chemical characteristics. Gut contents of trout, crayfish and eels were also examined to evaluate whether competiti
The objective was to explore the impact on physical health of a lifestyle programme among persons with psychiatric disabilities, and their caregivers. Their satisfaction with the intervention was also assessed. Somatic comorbidity and an increased mortality related to the lifestyle among persons with psychiatric disabilities are well known. Few randomized controlled trials have been aimed specific
Lipophilins A, B, C, mammaglobin, and uteroglobin are members of the secretoglobin family of small, secreted, proteins. The functions of these proteins are not well understood but uteroglobin has been implicated in the development of cancers. Uteroglobin is known to be highly expressed in normal lung and down-regulated in lung cancers but expression of the other secretoglobins in normal lung and l
The incidence of invasive group B streptococcus (GBS) infections in non-pregnant adults is increasing. Little is known about GBS in periprosthetic joint infections (PJIs). We aimed to analyse the clinical presentation of GBS PJI and its treatment in association with the outcome. The characteristics of 36 GBS PJIs collected from 10 centres were investigated. In 34 episodes, follow-up examination of
Cervical dystonia is a neurological movement disorder causing abnormal posture of the head. It may be accompanied by involuntary movements which are sometimes tremulous. The condition has marked effects on patients' self-image, and adversely affects quality of life, social relationships and employment. Botulinum neurotoxin (BoNT) is the treatment of choice for CD and its efficacy and safety have b
Avhandlingen fokuserar på musikdramaturgi i opera som har en story. Jag tycker att min egen musik blir bättre när jag skriver opera än konsertverk, frågan är varför? Syftet är att undersöka förhållandet story och musik och hur det påverkar komponerandet. Förloppet är undersökningens utgångspunkt eftersom story och musik pågår parallellt i tiden. Den konstnärliga verksamheten tas metodiskt i anspråTitle: The Twofold Rhythm of Duration in Opera. The Musical Dramaturgy of the Car Radio Opera "Cleansing of the Soul through Fun and Games". This thesis focuses on musical dramaturgy in operas with a story. I believe my own music is better when I write operas than instrumental music. The question is why? The aim of this thesis is to investigate the relationship between story and music and see how
Osteoporosis and low bone strength in older people may be due to low bone mass accrual or elevated age-related loss of bone mass. The mechanisms underlying loss of bone mass have long been subjected to research. However, research has only started in the last decade to focus on strategies to increase bone mass:the current opinion is that childhood and adolescence are critical periods for building u
47,XXY (Klinefelter syndrome) is the most frequent sex chromosomal disorder and affects approximately one in 660 newborn boys. The syndrome is characterized by varying degrees of cognitive, social, behavioral, and learning difficulties and in adulthood additionally primary testicular failure with small testes, hypergonadotropic hypogonadism, tall stature, and eunuchoid body proportions. The phenot
Mollusks have received increasing interest in ecotoxicological studies but so far the available scientific analyses of how their genes are affected by anthropogenic pollutants are scarce. The focus of this study is to identify an estrogen receptor (er) gene in the common prosobranch snail Bithynia tentaculata and to test a hypothesis that 17α-Ethinylestradiol (EE2) will modulate er gene expression
