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PURPOSE. To demonstrate noninvasive imaging of human foveal capillary networks with a high-resolution, wide-field, dual-conjugate adaptive optics (DCAO) imaging instrument. METHODS. The foveal capillary networks of five healthy subjects with no previous history of ocular or neurologic disease or surgery were imaged with a novel high-resolution, wide-field DCAO instrument. The foveal avascular zone
Resource availability and limiting factors for bacterial growth during early stages of soil development (8-138 years) were studied along a chronosequence from the glacial forefield of the Damma glacier in the Swiss Alps. We determined bacterial growth (leucine incorporation) and we investigated which resource (C, N or P) limited bacterial growth in soils formed by the retreating glacier. The latte
During development, information about the three-dimensional shape and mechanical properties of the body is laid down in the synaptic connectivity of sensorimotor systems through adaptive mechanisms. This functional adaptation occurs through alteration of connection properties. Here, we characterize the differences between strong and weak connections in the nociceptive withdrawal reflex in adult de
Cystatins regulate tumour-associated cysteine proteases, however, their role in tumour progression is not clear yet. To assess their relevance in the progression of nonsmall cell lung cancer (NSCLC) the protein level, cysteine protease activity (CPI) and localization of type I (stefins A and B) and type H (C, E/M and F) cystatins were defined in tumours and control lung counterparts from 165 patie
In order to reduce the total enzyme consumption in high-solids static hydrolysis of nonwashed steam-exploded willow Salix caprea by mixed cellulase of Trichoderma reesei + Aspergillus foetidus, two different approaches were proposed. In the first case, the enzyme activity adsorbed on residual solids after extended hydrolysis was used for hydrolysis of the newly added substrate. The initial mixing
Isaac Levi has claimed that our reliance on the testimony of others, and on the testimony of the senses, commonly produces inconsistency in our set of full beliefs. This happens if what is reported is inconsistent with what we believe to be the case. Drawing on a conception of the role of beliefs in inquiry going back to Dewey, Levi has maintained that the inconsistent belief corpus is a state of
Background: Lack of generalized guidelines for DNA flow cytometric analysis (FCM) may be the main reason for its limited use in the clinical management of breast cancer. Methods: After an initial interlaboratory reproducibility study (Round 1), we concluded that it was the evaluation of the DNA histograms rather than the technical performance of the analysis that was the main reason for discordant
Measurements of DNA ploidy can be performed either with image cytometry (ICM) or flow cytometry (FCM); both methods provide independent prognostic information in primary breast cancer. The aim of the present investigation was to compare the two methods and to relate the findings to prognosis (median follow-up 42 months). Concordance in ploidy status (diploid, tetraploid, aneuploid) was obtained in
Temperature is a fundamental thermodynamic parameter used to describe physical, chemical and biological processes. Much effort is made to measure temperature accurately in a wide variety of applications, making temperature one of the most extensively measured parameters. In combustion as in many other applications, temperature plays a substantial role in helping to maintain an efficient and clean
PURPOSE: Mutations in the NDP gene give rise to a variety of eye diseases, including classic Norrie disease (ND), X-linked exudative vitreoretinopathy (EVRX), retinal telangiectasis (Coats disease), and advanced retinopathy of prematurity (ROP). The gene product is a cystine-knot-containing extracellular signaling molecule of unknown function. In the current study, gene expression was determined i
Mouse mammary tumor virus (MMTV)-like sequences have been found in up to 40% of breast cancer samples but in <2% of normal breast tissue samples from Australian women studied by our group. Screening of a larger and more diverse cohort of female breast cancer samples has now shown a correlation of MMTV-like sequences with the severity (grade) of breast cancer. Thirty-two percent (43 of 136) of fema
This paper focuses on the volatile organic compound emissions from baled municipal solid waste (MSW). The analytical methodology was based on sampling with adsorbent tubes once a month during seven occasions within a time period of 1 year. Automated analyses were carried Out on-line work-up with thermal desorption directly connected to a gas chromatograph-mass spectrometer. The effect of different
Most computers today are embedded, i.e. they are built into some products or system that is not perceived as a computer. It is highly desirable to use modern safe object-oriented software techniques for a rapid development of reliable systems. However, languages and run-time platforms for embedded systems have not kept up with the front line of language development. Reasons include complex and, in
Europeiska unionen har länge arbetat för att uppnå fri rörlighet på den inre marknaden. På de flesta områden har arbetet nått långt men det finns undantag. Hypotekslånemarknaden inom EU är, trots betydande ekonomisk storlek, inte harmoniserad och ett flertal hinder mot den fria rörligheten av kapital existerar. Fokus i uppsatsen ligger framförallt på harmonisering och införande av en europeisk hThe European Union has long worked to achieve free movement within the internal market. In most areas, work has come a long way but there are exceptions. The mortgage market in the EU, despite significant economic size, is not harmonized, and a number of obstacles to achieve free movement of capital exist. The focus of the essay is primarily on the harmonization and implementation of a European
Despite the fact that men dominate substance abuse research and that most programs to target substance abuse therefore are developed by and for men, very little is known about the fact that substance abusing men can also be parents. Mothers are up until today regarded as the most important parent even though society is changing and fathers are taken a more active part in childrearing. The average
Purpose: This paper aims to uncover the associations and expectations consumers develop from a brand taking a political or social stance. We build upon existing literature to offer managers, and the research field, valuable insights to bridge the knowledge gap on what to consider before taking a stance. This paper guides the reader through a set of key considerations to evaluate before taking acti
With the sustainable potential of the city as a starting point, this thesis examines brownfield redevelopment in an existing urban context. The Nørrebro neighborhood of Copenhagen serves as a case. The focus is on learning from and reinterpreting existing urban structure, hierarchy, density and scale. Legislation allowing car free development at the chosen site, Vingelodden, also prompts explorati
The thesis investigates the perceptions about the importance of sustainability issues in the Millennial generation and the connection of the results to sustainability accounting to show how useful it is. The focus is particularly on sustainability as a criterion for job decisions and the extent to which it influences the motivation at work. In addition, differences in perception about age, gender,
Thirty years after the fall of communism and fifteen years after Poland joined the European Union, there have been more steps backwards than forwards in regards to gender and sexual equality. From the very beginning, this has been a cause of tension between Poland and the EU. The aim of this thesis is to investigate how the conflicting constructs of sexual citizenship in Poland and Europe affect t
The purpose of this study is to explore identity dynamics in mergers and acquisitions. As Clark, Gioia, Ketchen and Thomas (2010) point out, traditional economic perspectives are often not sufficient in explaining merger outcomes. Extant research on identity largely take a functionalist approach and frequently use quantitative methods, not taking the individual seriously. In contrast, we want to b
