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Background: Liver cirrhosis is associated with osteoporosis and liver transplantation (LT) with increased bone loss. This study aimed to in LT candidates investigate the potential relation between bone mineral density (BMD) and BMD loss in those who undergo LT, with malnutrition, systemic inflammation, and hormonal status. Methods: We included 102 consecutively recruited cirrhotic LT candidates be
BACKGROUND: Staphylococcus lugdunensis belongs to the CoNS group, but is regarded to be more virulent than most other CoNS. It is also remarkably susceptible to antibiotics, including penicillin G. OBJECTIVES: To evaluate different methods for penicillin susceptibility testing, to assess penicillin susceptibility rates among S. lugdunensis and to describe the clinical presentation including antibi
Developing and evaluating scientific knowledge and its value requires a clear – or at least not too unclear – understanding of what ‘theory’ means. We argue that common definitions of theory are too restrictive, as they do not acknowledge the existence of multiple kinds of scientific knowledge, but largely recognize only one kind as ‘theory’, namely explanatory knowledge. We elaborate a typology t
Background: Pediatric allergic contact dermatitis is increasing. The patch-test allergens included in pediatric baseline series vary globally. The worldwide prevalence of pediatric reactions to allergens needs clarification. Objectives: Identify the prevalence, associated factors, and culprit allergens for contact allergy among patch-tested Thai children, and compare with those for adults. Methods
Purpose: Onyx® embolization causes severe artifacts on subsequent CT-examinations, thereby seriously limiting the diagnostic quality. The purpose of this work was to compare the diagnostic quality of the tailored metal artifact reducing algorithms iMAR to standard reconstructions of CTA in patients treated with Onyx® embolization. Method: Twelve consecutive patients examined with Dual Energy CTA a
Mitochondrial creatine kinase (Mi-CK) consists of octameric and dimeric molecules that are interconvertible. In the present study, the kinetic properties of purified chicken heart Mi-CK (Mi(b)-CK) dimers and octamers were investigated separately under highly controlled conditions. Gel-permeation chromatography was performed before and after kinetic measurements in order to clearly define the propo
The results presented are the first examples where organotitanium reagents induced alkylative endo-cleavage of carbohydrates. The best conditions for the alkylative transfer of a methyl group to benzyl 2-deoxy- 2-C-methyl-4-O-(tert-butyldimethylsilyl)-α-D-arabinopyranoside (1) were the application of one equivalent of AlMe3 followed by four equivalents of MeTiCl3 generated by mixing TiCl4 and ZnMe
PURPOSE: Advanced glycation end products (AGEs) can be formed in foods by the reaction of reducing sugars with proteins, and have been shown to induce insulin resistance and obesity in experimental studies. We examined the association between dietary AGEs intake and changes in body weight in adults over an average of 5 years of follow-up.METHODS: A total of 255,170 participants aged 25-70 years we
The effect of insulin secretagogues on the incorporation of [32P]ortho-phosphate into phospholipids was studied in microdissected islets from obese-hyperglycemic mice. Increased 32P-labelling was observed after incubation for 60 min with 10 mM l-leucine, 10 mM l-arginine or 20 mM d-glucose. Most of the label occurred in the phosphatidyl inositol fraction. The effect of l-leucine was additive to th
Next to the redesign of industrial products and processes, sustainable business model innovation is a strategic approach to integrate environmental and social concerns into the objectives and operations of organizations. One of the major challenges of this approach is that many promising business model ideas fail to reach the market, which is needed to achieve impact. In the literature, the issue
Activation of the kynurenine pathway (KP) has been reported in patients with pulmonary arterial hypertension (PAH) undergoing PAH therapy. We aimed to determine KP-metabolism in treatment-naïve PAH patients, investigate its prognostic values, evaluate the effect of PAH therapy on KP-metabolites and identify cytokines responsible for altered KP-metabolism. KP-metabolite levels were determined in pl
Ovarian clear cell carcinomas (OCCC) constitute a rare subtype of epithelial ovarian cancer, lacking efficient treatment options. Based on previous studies, we assessed the anti-proliferative effect of simvastatin, a Rho GTPase interfering drug, in three OCCC cell lines: JHOC-5, OVMANA and TOV-21G, and one high-grade serous ovarian cancer (HGSOC) cell line, Caov3. We used the Rho GTPase interferin
Lund presenteras som en medeltidsstad, och visst har staden sitt ursprung i medeltiden, men periodbeteckningen är en eftermedeltida konstruktion och de bevarade spåren är färre än man kan förledas tro. I artikeln genomgås vad som finns kvar av från medeltiden – domkyrkan, Liberiet, Klosterkyrkan, ruinen av sockenkyrkorna Maria Minor och Drotten, Krognoshuset, Dekan- och Kanikresidenset, stadsvalle
Background: People with Parkinson’s disease (PD) have described their walking difficulties as linked to activity avoidance, social isolation, reduced independence and quality of life. There is a knowledge gap regarding predictive factors of perceived walking difficulties in people with PD. Such knowledge could be useful when designing intervention studies. This study aimed to investigate how perce
Background: EU workers exposed to hand-arm vibration should be offered health surveillance to detect early symptoms, and findings, of Hand-Arm Vibration Syndrome (HAVS). To execute the mandatory vocational rehabilitation, the employer needs to be aware of injuries found in the medical check-up. We aimed to analyse: 1) How physicians graded the neurosensory component of HAVS on the Stockholm Worksh
At the heart of this research are relational encounters between people and textile materials. As the title, Crafting Material Bodies, indicates, the research explores how human bodies are crafted by material bodies (costume) and vice versa. In the research textile materials and people are my co-creators and as co-creators they are invited to relate to, affect and become affected by other human bod
En välkänd svårighet för inlärare av L2-svenska är komplexiteten kring definithet, bestämdhet och artikelbruk (DBA). Flera studier har indikerat att inlärare som saknar morfologisk bestämdhetsmarkering i sitt L1 har svårare för strukturer inom DBA, men att även inlärare med motsvarande strukturer i sitt L1 har rapporterats ha svårigheter. I denna artikel redogör vi för hur den komplexitet som DBA A well-known difficulty for learners of L2 Swedish is the complexity of definiteness in form and meaning, together with article use. Several studies have indicated that learners lacking morphological definiteness in their L1 struggle more with structures within this area although learners with corresponding structures in their L1 also have issues. This article describes how this area’s complexity
