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Background: Depression is linked with alexithymia, anxiety, high HbA1c concentrations, disturbances of cortisol secretion, increased prevalence of diabetes complications and all-cause mortality. The psycho-educational method 'affect school with script analysis' and the mind-body therapy 'basic body awareness treatment' will be trialled in patients with diabetes, high HbA1c concentrations and psych
Purpose: Patients with a bipolar I disorder (BD-I) manic episode meeting the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5), criteria for "with mixed features" have a high incidence of suicide attempts and of anxiety, irritability, and agitation (AIA) symptoms. The aim of this analysis was to explore the relationship between suicidality and AIA symptoms in patients wi
För att skapa matematiska beskrivningar av fysiska fenomen inom bland annat naturvetenskap, teknik och medicin används ofta partiella differentialekvationer. Listan med tillämpningar kan göras hur lång som helst: sådana ekvationer kan beskriva hur en snöflinga bildas, hur strukturer deformeras när de utsätts för mekaniska krafter, hur partiklar interagerar på kvantnivå, hur blodet flödar i hjärnanSplitting methods are widely used temporal approximation schemes for parabolic partial differential equations (PDEs). These schemes may be very efficient when a problem can be naturally decomposed into multiple parts. In this thesis, splitting methods are analysed when applied to spatial splittings (partitions of the computational domain) and physical splittings (separations of physical processes)
Popular Abstract in Swedish Reumatoid artrit Reumatoid artrit (RA), på svenska ledgångsreumatism, är den vanligaste kroniska, inflammatoriska ledsjukdomen (artriten) bland människor. I Sverige är förekomsten i befolkningen omkring 0,7%, och bland 100 000 personer insjuknar ca. 50 årligen med denna diagnos. Könsfördelningen är dock ojämn, med en mer än dubbelt så stor risk för kvinnor att utvecklaObjectives: To study: (I) the impact on cost-utility analyses of applying different national EuroQol 5-Dimensions (EQ-5D) preference sets; (II and III) whether, in methotrexate-refractory, early rheumatoid arthritis (RA), the addition of infliximab results in superior health-related quality of life (HRQoL) and may be considered cost-effective, as compared to adding sulfasalazine and hydroxychloroq
Background: The intervention; "Continuum of Care for Frail Older People", was designed to create an integrated continuum of care from the hospital emergency department through the hospital and back to the older person's own home. The aim of this study is to evaluate the effects of the intervention on functional ability in terms of activities of daily living (ADL). Methods: The study is a non-blind
Objective: Glucose degradation products (GDPs) in peritoneal dialysis (PD) fluids are cytotoxic and affect the survival of the peritoneal membrane. One of the most reactive GDPs in PD fluids is 3,4-dideoxyglucosone-3-ene (3,4-DGE). 3,4-DGE has been reported as an intermediate between 3-deoxyglucosone (3-DG) and 5-hydroxymethyl furaldehyde (5-HMF) during degradation of glucose. In PD fluids, 3,4-DG
Bakgrund: Generellt bland industrivärldens lager är denhuvudsakliga uppgiften försörjning av material mot montering och tillverkning. Så är fallet även på ABB Swedewater. När en produkt ska tillverkas plockar personalen på lagret ihop de komponenter som behövs och skickar dem till tillverkningen. Materialet till anläggningen ”kittas” för att underlätta arbetet i produktion. Detta betonar vikten avBackground: Generally among industrialized warehouses, the main operational task is to supply the assembly or manufacturing with material, so is also the situation at ABB Swedewater. When manufacturing a product, the warehouse personnel pick necessary components requested by othersections of the production. This stresses the importance of a correct performance when picking, as this forms the base
Abstract Sexual selection is considered to be one of the most important processes influencing the evolution and diversification of species. Sexual conflict, a subset of sexual selection theory, describes how opposing interests in the male and female reproductive systems can lead to one sex increasing its fitness at a cost to the other sex. Traits involved in this conflict may come under selection
Protein design can be used to make better variants of a protein by changing the primary structure of proteins. An assay is needed to select for a better protein variant, generally these assays work on proteins with an activity. But sometimes proteins are designed to obtain a specific structure instead of an activity or function. These proteins often have no activity and there is no easy way to sel
Cardiovascular (CVD) is one of the most common causes of mortality. Apart from known causal risk factors such as smoking, obesity, dyslipidaemia and hypertension, chronic psychological stress has been suggested as a possible independent risk marker, also because the CVD burden follows a social gradient. Another self-reported variable is self-rated health (SRH) which in many studies has ben shown t
Konkurrensrätt och immaterialrätt har länge betraktats vara rättsområden som skyddar motstående intressen. En av de regleringar som finns för att underlätta förhållandet mellan de två rättsområdena är kommissionens förordning nr 772/2004 för grupper av avtal om tekniköverföring. Genom denna förordning önskar kommissionen garantera en effektiv konkurrens på marknaden samt erbjuda företag som ingår Competition Law and Intellectual Property Law are sometimes considered as areas of law which protect conflicting interests. One of the regulations striving to facilitate the relationship between these two areas is Regulation 772/2004, on the application of article 101.1 TFEU to categories of technology transfer agreements. The objectives of this Regulation are to ensure effective competition and t
Digitaliseringen i samhället breder ut sig i allt större omfattning. Utvecklingen öppnar upp för en mängd möjligheter men kommer även med en hel del utmaningar. Processer som tidigare varit beroende av manuella förfarande kan nu hanteras helt automatiskt. Detta gäller exempelvis möjligheten att fatta automatiserade beslut inom den offentliga förvaltningen. AI möjliggör för mer komplicerade uppgiftDigitalization in our society is rapidly extending into new areas. The development opens up for many possibilities but also brings a number of challenges. Processes that were earlier dependent on manual procedures can now be managed automatically. This can for example be carried out through automated decision-making within the public administration. For more complicated tasks AI can extend the pos
Systemic Lupus Erythematosus (SLE) is an autoimmune disease where the immune system is attacking the body and its tissues. This leads to a chronic inflammation that can affect different parts of the body and therefore present itself in a vast variety of symptoms. Depending on the activity of the disease it can go up in flares where the patients experience symptoms and then go down into recession.
The field of linguistic relativity has its origin in the thoughts of the German philosopher Humboldt. He considered the language to be the formative organ of thought, the thought becomes externalized through sound in speech and thus perceptible to the senses. Thought and language are therefore one and inseparable from each other. Other prominent names in the field of linguistic relativity are Sapi
New and innovative retail models such as product-service-systems (PSS) seem to offer a promising solution for more sustainable shopping activities. However, the adoption rate of PSS remains to date regretfully low. With the aim to investigate this problem, the present thesis focuses on the rental fashion model of use-oriented PSS and examines emotions that consumers experience in this context, whe
Soft biological tissues and engineered hydrogels for biomedical applications are intrinsically multiphasic materials, consisting of solid, fluid and possibly fixed and mobile ions. Understanding their mechanical behaviour requires experimental methods and theoretical models that take their multiphasic nature into account and allow for quantification of material parameters related to the different
All judicial power is to be condemned by the law according to the Swedish constitution but does this apply to a frame law where there is a legal gap that the decision makers can fill with other norms than legal norms? According to the paradigm of sociology of law do other factors than just legal norms affect the judicial decision. This means that the judicial decisions might be affected by factors
Background/Problematization: Iconic brands are the gold standard of branding and have established a central role in the consumers’ lives. Behind every iconic brand, we can find iconic products. Despite the importance of these products, iconic products are overlooked in academia. Few studies have explored the concept and there is no common definition or comprehensive framework. This is restrictive
All around in our bodies – inside and on top of cells, as well as in the extracellular matrix (ECM) – complex carbohydrate chains known as glycosaminoglycans (GAGs) are to be found. While some of their properties are known, many functions and biosynthetic pathways remain undiscovered. Heparin is one of the GAGs whose function in the body is not completely known, however, it has been used as an ant
