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Isaac Levi is more interested in inquiry and how it progresses than he is in metaphysics. Questions concerning the role of disposition predicates in inquiry are more central to him than those concerning the nature and reality of dispositions. It has not stopped him from giving me and others very useful metaphysical advice. Currently, where empirical metaphysics is in vogue, there is every reason t
This paper suggests a stochastic volatility term-structure model applied to the pricing of electricity swaptions in the Nord Pool market. The volatility structure in the model is specified as a product of a time-dependent function that handles the maturity effect, and a Cox-Ingersoll-Ross process that captures the volatility smile. We employ a Fourier based approach to price electricity swaptions
Analysis of pollen and spore assemblages from both terrestrial and near-shore marine sediments in New Zealand reveal an instant and dramatic mass-kill of the land plants in close association with the Cretaceous-Tertiary boundary (KTB) event. The turnover in the palynoflora is followed by a recovery succession, the most prominent feature of which is an interval dominated by fern spores (fern spike)
The PHENIX experiment is one of the two large experiments at RHIC. It addresses most of the signals suggested from the Quark-Gluon Plasma. This paper focuses on the measurements of global observables and identified hadron spectra and particle ratios from the two first runs with Au+Au collisions at 130A GeV and 200A GeV. The energy density reached in the most central collisions is about 5 GeV/fm(3)
We study the stability of systems of three giant planets orbiting 3-8 M☉ stars at orbital distances of >10 au as the host star ages through the main sequence (MS) and well into the white dwarf (WD) stage. Systems are stable on the MS if the planets are separated by more than ~9 Hill radii. Most systems surviving the MS will remain stable until the WD phase, although planets scattered on to small p
Reasoning with limited computational resources (such as time or memory) is an important problem, in particular in cognitive embedded systems. Classical logic is usually considered inappropriate for this purpose as no guarantees regarding deadlines can be made. One of the more interesting approaches to address this problem is built around the concept of active logics. Although a step in the right d
We introduce two novel joint radio-frequency (RF)-baseband designs for receivers in a MIMO system with Nt transmit antennas, Nr receive antennas, but only L < Nr RF chains at the receiver. The joint design introduces an RF pre-processing matrix that processes the signals from the different antennas, and is followed by selection (if necessary), down-conversion, and further processing in the baseban
A platform for rapid on-line protein digestion of protein mixtures for direct infusion to a mass spectrometer is presented. A mixture of protein A, staphylococcal enterotoxin B and cytochrome c was used as a model mixture injected on a gel filtration column and a trypsin reactor which were connected in series to a micro liquid chromatography (mu LC) system. The peptides in the column eluate were a
Current proteomic technologies can effectively be used to study the proteins of the vitreous body and retina in health and disease. The use of appropriate samples, analytical platform and bioinformatic method are essential factors to consider when undertaking such studies. Certain proteins may hinder the detection and evaluation of more relevant proteins associated with pathological processes if n
1.Migration is a widespread phenomenon, with powerful ecological and evolutionary consequences. Morphological adaptations to reduce the energetic costs associated with migratory transport are commonly documented for migratory species. However few studies have investigated whether variation in body morphology can be explained by variation in migratory strategy within a species. 2.We address this qu
Whether chromosome abnormalities observed in tumor cells may in some cases reflect low-grade somatic mosaicism for anomalies present already at zygote formation, rather than acquired somatic mutations, has for long remained a speculation. We here report a patient with Wilms tumor, where constitutional somatic mosaicism of trisomy 8 was detected in a previously healthy 2 ½-year-old boy. Single Nucl
Male breast cancer (MBC) is a rare disease that shares both similarities and differences with female breast cancer (FBC). The aim of this study was to assess genome-wide DNA methylation profiles in MBC and compare them with the previously identified transcriptional subgroups of MBC, luminal M1 and M2, as well as the intrinsic subtypes of FBC. Illumina's 450K Infinium arrays were applied to 47 MBC
During sporulation of Streptomyces coelicolor, the cytokinetic protein FtsZ is assembled into dozens of regularly spaced Z rings, which orchestrate the division of aerial hyphae into spores. We have previously found that a missense allele of ftsZ, ftsZ17(Spo), primarily affects sporulation septation rather than formation of cross-walls in vegetative mycelium. To clarify what aspect of FtsZ functio
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and adolescents. Alveolar (ARMS) and embryonal (ERMS) histologies predominate, but rare cases are classified as spindle cell/sclerosing (SRMS). For treatment stratification, RMS is further subclassified as fusion-positive (FP-RMS) or fusion-negative (FN-RMS), depending on whether a gene fusion involving PAX3 or PAX7 is prese
Previous research (Libby et al., 2009) has established that a third-person (outside) visual perspective elicits more abstract processing than a first-person (inside) perspective. Because many moral principles constitute abstract psychological constructs, we predicted that they should weigh more heavily when people adopt a third-person visual perspective. In two experiments we show that a third- (v
Summary The CAG repeat in the androgen receptor (AR) has been widely studied in association with male infertility, but the results are conflicting. In a recent meta-analysis, infertile men had <1 repeat longer CAG stretch than fertile men when analysed in a linear regression model assuming that AR function diminishes with increasing CAG length. However, in vitro, a non-linear activity pattern was
Popular Abstract in Swedish Fysiologisk integrering och morfologisk plasiticitet i stora klonala växter Många av våra vanligaste växter är klonala, dvs de kan producera avkommor utan sexuell befruktning. Hit räknas blåbär och lingon, många av våra vårväxter som tex. vitsippa och flera av våra värsta ogräs, som kvickrot och kirskål. En fördel som klonala växter har är att dotterskott som fortsätteClonal plants show a large variation in physiological integration, i.e. the translocation of resources among ramets within the clone. As resource transport is costly, we hypothesized that plants from poor sites should be more highly integrated than plants from rich sites and that plants would benefit if they were plastic in their degree of integration. Tracers were used to study the transport of w
We recently reported that a red meat (beef) diet relative to a casein-based diet increases protein kinase C (PKC) activity in rat colonic mucosa. The purpose of this study was to further elucidate the effects of a high-beef diet on colonic intracellular signal transduction by analyzing steady-state protein levels of different PKC isozymes as well as activities of the three types of sphingomyelinas
