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BACKGROUND: Asthma guidelines recommend that long-acting inhaled beta-agonists should be used as maintenance therapy for patients with asthma inadequately controlled on an inhaled corticosteroid. We studied the safety and efficacy of the long-acting beta-agonist formoterol compared with terbutaline, each taken as needed, in patients with moderate to severe asthma. METHODS: Patients were taking an
Uncoupling-protein 2 (UCP2) is a mitochondrial protein that appears to be involved in cellular oxidant defense and in the regulation of oncotic cell death, both of which are important features of acute pancreatitis. However, UCP2 expression in acute pancreatitis has not been previously reported. In the current experiments, pancreatic gene expression was studied by real-time reverse-transcription/p
Treatment with alkali, particularly overliming, has been widely used as a method for the detoxification of lignocellulose hydrolysates prior to ethanolic fermentation. However, the mechanisms behind the detoxification effect and the influence of the choice of cation have not been well understood. In this study, a dilute acid hydrolysate of spruce and an inhibitor cocktail consisting of six known i
Objective. Previous population studies have suggested that both rheumatoid factor (RF) production and rheumatoid arthritis (RA) may be declining in occurrence, and. both secular and birth-cohort influences have been implicated. Since Pima Indians have a very high incidence of RA and also have shown recent evidence or a decline in RA, this study evaluated the relative contributions of age, secular,
Six adult and three juvenile honey buzzards Pernis apivorus were radio-tracked by satellite during autumn migration from southwestern Sweden. All adults crossed the Mediterranean Sea at the Strait of Gibraltar and continued across the Sahara desert to winter in West Africa, from Sierra Leone to Cameroon. Analysing three main steps of the migration, (1) from the breeding site to the southern Medite
During the last 10-15 years, the implantable cardioverter-defibrillator (ICD) has become an important mode of treatment for patients suffering from grave ventricular arrhythmias, but ICD implantation involves psychosocial adjustments for both patients and relatives. The aim of this pilot study was to design a plan of education and to follow a selected group of patients with interviews, observation
The development of metal tolerance in soil bacterial communities exposed to different heavy metals was examined under laboratory conditions. An agricultural soil amended with different Zn concentrations was studied most intensively, and measurements were made over a 28-month incubation period by means of the thymidine incorporation technique. Tolerance levels were not affected by metal concentrati
Aim: To investigate patients' psychological distress in relation to memory and stressful experiences in the intensive care unit (ICU), and to identify early predictors for the development of high levels of acute post-traumatic stress disorder (PTSD)-related symptoms. Methods: A prospective cohort study was performed over 18 months in two general ICUs, including 313 intubated mechanically ventilate
Polysulfone ultrafiltration membranes were modified with dextran, dextran sulfate and diethylaminoethyl (DEAE) dextran. The behavior of the modified membranes towards static adsorption of bovine serum albumin (BSA) was investigated in the pH range 3-7. The modified membranes showed lower flux losses after protein adsorption than unmodified membranes. The plain dextran was considered to be the best
The aim of this study was to analyze how preschool principals talk about their obligation to report child maltreatment to social services. Five principals, from five different local areas, were interviewed in the study. Two of the preschools were situated in underprivileged areas, and the others in economically and socially fairly well situated areas. Discourse analysis was applied in the examinat
Based on the feasibility study [4], the goal of this master thesis is to compile custom firmware for the XM112 Pulsed Coherent Radar Module, which features a state of the art radar sensor integrated with a microcontroller unit (MCU). This allows the use of custom firmware to check the plausibility of real-time data processing on the radar signals and will lay some of the groundwork for further dev
Syftet med projektet var att utvärdera katalysatorer med olika formuleringar för pre-reformingprocessen. Tre av de fem som testades tillverkades av studenten genom incipient wetness impregnation-metoden. BET-analys visade att katalysatorerna med Θ-alumina hade störst porvolym, den med γ-alumina hade däremot störst ytarea. Testerna gjordes i en tubreaktor som hade gasutloppet kopplat till en GC förThe purpose of this project was to perform a screening on catalysts with different formulations for the pre-reforming process. Three of the five catalysts tested were made by the student using the incipient wetness impregnation method. BET analysis showed that the catalysts with Θ-alumina had the greatest pore volume, while the one with γ-alumina had the greatest surface area. The tests were done
Med en ökad medellivslängd ökar även antalet äldre arbetstagare på arbetsmarknaden. Frågan om äldre arbetstagares rättigheter och skyldigheter på arbetsplatsen blir därmed mer och mer aktuell. I Sverige men först och främst inom EU har det införts diskrimineringsförbud som innebär att äldre såväl som yngre arbetstagare skyddas från att missgynnas på grund av sin ålder på arbetsplatsen. Både svenskA continuously aging population leads to an increase in senior employees in the labor market. A question about the rights and duties for these employees is thereby raised more frequently than ever. Within the EU and in Sweden a prohibition against discrimination has been introduced to protect both younger and older employees. Both legislations, however, have an exception from this prohibition whic
Sverige brukar få hög placering i internationella jämförelser av sjukvårdssystem. Det gäller inte minst patientnöjdhet och kvalitet, läkartäthet och hälsoutfall. Ändå har de senaste åren varit mycket vanligt med larmrapporter om kris på sjukhusen med påstådda överfulla vårdsalar och personal som lämnar sjukvården pga för hög arbetsbörda och ohållbar arbetsmiljö. Situationen har dragit igång debattData Envelopment Analysis (DEA) which compares different Decision Making Units (DMUs) has been used by some scholars to find the most efficient hospitals within Sweden or within Nordic countries. In Sweden, healthcare is decentralized and provided mostly by the 21 county councils. Even private providers have to sign contracts with the county councils in order to be permitted to operate within thei
Food consumption is a big part of the global emissions, which we need to address to increase the pace in the climate transition. In order to prevent further increase in greenhouse gas emissions a shift in milk consumption towards more plant- based options is needed. The aim of this study is to increase the understanding of how the relationship between consumers attitudes towards sustainability and
Regime shifts in shallow lakes are typically characterized by submerged macrophyte (clear water regime) or phytoplankton (turbid regime) dominance. Climate warming is expected to affect water quality and facilitate turbidity in lakes, but we may also expect synergistic effects on organisms' interactions from climate and local specific dynamics in lakes. We here examined long-term changes in phytop
Background: A delay in surgical nerve repair results in impaired nerve function in humans, but mechanisms behind the weakened nerve regeneration are not known. Activating transcription factor 3 (ATF3) increases the intrinsic growth state of injured neurons early after injury, but the role of long-term changes and their relation to axonal outgrowth after a delayed nerve repair are not well understo
BACKGROUND AND OBJECTIVES: Transfusion of blood products in particular older products is associated with patient morbidity. Previously, we demonstrated a higher incidence of acute lung injury in lipopolysaccharide-treated sheep transfused with stored blood products. As transfusion following haemorrhage is more common, we aimed to determine whether a 'first hit' of isolated haemorrhage would prec
