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Background: There is an urgent need to improve patient safety in the area of medication treatment among the elderly. The aim of this study was to explore which improvement needs and strengths, relating to medication safety, arise from a multi-professional intervention in primary care and further to describe and follow up on the agreements for change that were established within the intervention. M
The problem of antibiotic resistance is rising continuously, creating a warning signal that calls for finding alternatives. Not only that, but there is also a rising demand for natural food preservatives. The pharmaceutical and food industry sectors are working on fulfilling these needs. This thesis is exploring possible solutions to these issues. The research studies presented here introduce the
BACKGROUND: We sought to identify potential clinical variables associated with outcomes after radium-223 therapy in routine practice. METHODS: Consecutive non-trial mCRPC patients who received ≥1 dose of radium dichloride-223 at four academic and one community urology-specific cancer centers from May 2013 to June 2014 were retrospectively identified. Association of baseline and on-therapy clinical
A total of 1280 80-year-old men in the community of Malmö were questioned about smoking habits and the occurrence of cardiovascular disease (CVD). After a careful medical and duplex ultrasound examination, four groups were selected for further studies: (1) no CVD, non-smokers: (2) no CVD, smokers: (3) CVD, smokers: (4) CVD, non-smokers. In total 122 individuals participated. The average tobacco co
Cloud computing technology provides the means to share physical resources among multiple users and data center ten- ants by exposing them as virtual resources. There is a strong industrial drive to use similar technology and concepts to provide timing sensitive services. One such is virtual net- working services, so called services chains, which consist of several interconnected virtual network fu
Purpose: To investigate associated systemic diseases, other conditions, visual outcome, ocular complications and treatment in Swedish patients younger than 50 years with central retinal vein occlusion (CRVO) and reviewing the literature. Methods: Twenty-two patients with CRVO, younger than 50 years, were examined with full-field electroretinography (ERG) within 3 months after a thrombotic event, o
Electric vehicles (EVs) are increasingly seen as a desirable sustainable solution for the transport sector, and public procurement is often highlighted as one tool to stimulate a market. In this paper, we analyse the role of Swedish municipalities in relation to public procurement and especially whether and in such cases how municipalities in Sweden use public procurement as an instrument to enhan
Diverse radiations of insects are often associated with adaptations to host plants, and well-resolved phylogenetic relationships are required to fully understand them. Palearctic Argynnis and related subgenera, together with North American Speyeria butterflies make up a radiation whose species hypotheses are confounded by shared wing colour patterns between sympatric populations of closely related
Background - Genome-wide association studies have recently identified >400 loci that harbor DNA sequence variants that influence blood pressure (BP). Our earlier studies identified and validated 56 single nucleotide variants (SNVs) associated with BP from meta-analyses of exome chip genotype data. An additional 100 variants yielded suggestive evidence of association. Methods and Results - Here, we
Resource sharing in heterogeneous environments has been shown to increase growth and survival of clonal plants. In addition, plants in harsh climates have been suggested to have higher levels of resource sharing than plants in milder climates. We experimentally investigated the level of resource sharing in plants from garden and forest habitats from two regions with contrasting climates. The clona
The prognostic impact of body mass index ( BMI) in patients following acute myocardial infarction ( AMI) may be altered by neurohormonal blockade. Methods: The impact of neurohormonal blockade on the association between BMI and mortality was examined in 5548 patients following AMI ( CONSENSUS II), 50% receiving enalapril and 7% beta- blockade, and in 4367 patients with coronary artery disease ( CA
In healthy subjects, acute inhalation of swine dust causes an influx of inflammatory cells into the airways and increased bronchial responsiveness. The exposure may also cause fever and generalized symptoms. It seems likely that proinflammatory cytokines are involved in the response to inhaled swine dust. Nasal and bronchoalveolar lavage (BAL) were performed before, and 7 and 24 h after the start
STUDY OBJECTIVE: To evaluate postoperative breathing patterns with a new monitoring device in patients given bupivacaine-morphine epidural analgesia. DESIGN: Open explorative study. SETTING: Inpatient anesthesia in a university hospital setting. PATIENTS: 15 ASA physical status I and II patients aged 28 to 87 years and scheduled for major abdominal surgery. INTERVENTIONS: All patients underwent ab
Previous studies suggest that obesity is related to increased risk of renal cell carcinoma (RCC); however, only a few studies report on measures of central vs. peripheral adiposity. We examined the association between anthropometric measures, including waist and hip circumference and RCC risk among 348,550 men and women free of cancer at baseline from 8 countries of the European Prospective Invest
We have developed a technique to image the near-field liquid core within an atomizing spray. To obtain high-fidelity images of the liquid core in such a spray has been very challenging up to this point. In this article, however, we describe the successful use of a time-gated ballistic imaging instrument to obtain high spatial resolution, single-shot images of the liquid core in an atomizing water
The study investigated the effect of positive and negative emotional valence (I.A.P.S pictures) on recollective experience, using the remember-know paradigm (Tulving, 1985), and confidence judgements. The negative valenced pictures were hypothesised elicit the recollective experience to a larger extent and to entail a higher degree of confidence in the correctness of memory responses than positive
Twist extrusion (TE) is known as one of newly developed, but still moderately studied severe plastic deformation methods. This research was initiated to conduct a detailed study of structure-properties relationship evolution during TE processing. The evolution of macrostructure, Vickers hardness and tensile properties was studied in 99.99% purity aluminum during twist extrusion processing at room
