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Background: Repolarization prolongation can be the earliest electrophysiological change in ischemia, but its role in arrhythmogenesis is unclear. The aim of the present study was to evaluate the early ischemic action potential duration (APD) prolongation concerning its causes, expression in ECG and association with early ischemic ventricular fibrillation (phase 1A VF). Methods: Coronary occlusion
PURPOSE: The Swedish InfCareHIV cohort was established in 2003 to ensure equal and effective care of people living with HIV (PLHIV) and enable long-term follow-up. InfCareHIV functions equally as a decision support system as a quality registry, ensuring up-to-date data reported in real time.PARTICIPANTS: InfCareHIV includes data on >99% of all people with diagnosed HIV in Sweden and up to now 13 0
Judith Korth joins the podcast this week and tell us about how she found her way into astronomy research, how she ended up here at Lund University and how she now studies distant worlds far beyond our own Solar System.In this third season we are also including some Cosmic Curiosities. These are some ideas, events or trivia from astronomic history that Ross, Victor and Lucian feel are worth bringin
Wetland bird species have been declining in population size worldwide as climate warming and land-use change affect their suitable habitats. We used species distribution models (SDMs) to predict changes in range dynamics for 64 non-passerine wetland birds breeding in Europe, including range size, position of centroid, and margins. We fitted the SDMs with data collected for the first European Breed
Circulatory failure is considered one of the entities of the post cardiac arrest syndrome contributing to poor outcome. It is reported at 15-70% of all patients successfully resuscitated from out-of-hospital cardiac arrest (OHCA). The pathophysiologic mechanism is attributed to limitation of cell metabolism due to inadequate supply of oxygen, caused by pump or conduction failure within the cardiov
The aims of the study were 1). to investigate the association between the potential risk factors including socio-demographic, lifestyle and DNA methylation and mental disorders in middle-aged women from a large population-based follow-up study, and 2). to estimate the risk score by combining the potential risk factors to examine the mental disorder's incidence. A total of 6461 women, aged 50-65 ye
Background. Prostate specific antigen (PSA) is a zymogen of a 33‐kilodalton (kD) serine proteinase with extensive similarity to glandular kallikreins. The mechanism responsible for converting the zymogen into active proteinase has not been defined, but active PSA may be irreversibly inactivated in vitro by two of the major proteinase inhibitors in blood: alpha1‐antichymotrypsin and alpha2‐macroglo
Background: Adverse events induced by intravesical bacillus Calmette-Guérin (BCG) to treat high-grade non–muscle-invasive bladder cancer (NMIBC) often lead to treatment discontinuation. The EAU-RF NIMBUS trial found a reduced number of standard-dose BCG instillations to be inferior with the standard regimen. Nonetheless, it remains important to evaluate whether patients in the reduced BCG treatmen
Background: Rapid antigen detection tests (RADT) for Group A streptococci (GAS) and point-of-care tests for C-reactive protein (CRP) are commonly used in patients with pharyngotonsillitis in Sweden and Denmark although CRP testing is not supported by guidelines. We aimed to describe (1) the proportion of patients tested with RADT and/or CRP, (2) the relation between test results and antibiotic pre
Popular Abstract in Swedish I vårt dagliga liv kommer vi i kontakt med en rad produkter som tillverkas av arbetare som riskerar att drabbas av sjukdomar till följd av sin arbetsmiljö. De organiska syraanhydriderna är industriellt vanligt förekommande kemikalier. Två av dessa anhydrider har studerats i denna avhandling, nämligen hexahydroftalsyra anhydrid (HHPA) och methylhexahydroftalsyra anhydridThe aim of this thesis was to describe the metabolism and to develope methods for biological monitoring for two organic acid anhydrides (OAAs), namely hexahydrophthalic anhydride (HHPA) and methylhexa-hydrophthalic anhydride (MHHPA). The OAAs are reactive, low molecular weight chemicals used in vast quantities in the industry. Many OAAs, including HHPA and MHHPA, are potent IgE sensitisers inducin
Background: Practice guidelines for childhood posttraumatic stress disorder (PTSD) recommend trauma-focused psychotherapies, mainly cognitive behavioral therapy (CBT). Eye movement desensitization and reprocessing (EMDR) therapy is a brief trauma-focused, evidence-based treatment for PTSD in adults, but with few well-designed trials involving children and adolescents. Methods: Weconducted a single
In contrast to the efficient market hypothesis (EMH), the noisy market hypothesis (NMH) asserts that prices are but noisy indications of fundamental values. The authors study losses in certainty equivalents of investing according to one hypothesis (NMH or EMH) when the other is true. Their findings suggest that, for reasonable parameter values, investing according to the EMH when the NMH is true y
Denna uppsats undersöker hur självgynnande (“self-preferencing”) beteenden hos digitala plattformar i dominerande ställning behandlas rättsligt enligt artikel 102 FEUF. Syftet är att klargöra den nuvarande rättsliga situationen och skapa en mer sammanhängande förståelse genom att kombinera rättsdogmatisk metod och analys med rättsekonomiska resonemang. Analysen vägleds av tre delfrågor: den ekonomThis thesis explores the evolving legal treatment of self-preferencing by dominant digital platforms under Article 102 TFEU. It aims to clarify the current legal position and contribute to a more coherent understanding by combining legal doctrinal analysis with law-and-economics reasoning. Three sub-questions guide the analysis: the economic rationale behind self-preferencing, applicable theories
Assisterad befruktning har, vid sidan av internationella adoptioner, kommit att skapa möjligheter framför allt för de som lider av ofrivillig barnlöshet, att bilda familjer som inte är baserade på genetiska eller biologiska band. De olika metoderna för behandling av ofrivillig barnlöshet ger upphov till en rad etiska och juridiska frågor, bland annat om vilka metoder som ska tillåtas och vilka kraAssisted reproductive technology has, in addition to international adoptions, come to create opportunities, particularly for those who suffer from infertility, to form families that are not based on genetic or biological ties. The various methods of treating infertility raises a number of ethical and legal issues, including what methods are to be permitted and the requirements that must be met in
This paper investigates whether the information from a number of different economic variables have the ability to predict stock returns on the OMXS30. The estimated forecast models are evaluated with a number of standard metrics to find the best performing models. These models are then used in combination with two portfolio strategies and tested over different time periods and forecast horizons, t
Energy efficiency is key in our modern society, and in its pursuit, unexpected problems can appear. For instance, when Axis Communications in the pursuit of image quality and energy efficiency used strobing IR-illumination to illuminate for their global shutter cameras, they observed an artefact in the form of a white band in their rolling shutter cameras. The purpose of this thesis is to find a s
The aim of this paper is to evaluate potential leading indicators of a recession in Sweden. To answer the question potential leading indicators are first identified with previous findings in literature and with the current state of the Swedish financial system as background. Then these variables will be included in a probit regression at different forecasting horizons. The horizons are one, two an
In 2018, images of migrant children held in cages and sleeping on concrete floors while being held in immigration detention in the United States shocked the world. Within the framework of the zero tolerance policy on immigration mandated by President Trump, thousands of families have been separated at the border. The trauma borne out of these separations was purposefully capitalized upon to serve
