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CCL25/CCR9 promotes the induction and function of CD103 on intestinal intraepithelial lymphocytes.

The integrin CD103 and the chemokine receptor CCR9 are co-expressed on small intestinal CD8+ intraepithelial lymphocytes (IEL), naïve murine CD8+ T cells and by a small population of effector/memory CD8+ T cells, indicating a potential role for CCR9 in regulating CD103 expression and function. Here, we demonstrate that CD103, in contrast to CCR9, is down-regulated on CD8+ T cells following their a

Relational problems and psychiatric symptoms in couple therapy

Lundblad A-M, Hansson K. Relational problems and psychiatric symptoms in couple therapyInt J Soc Welfare 2005: 14: 256 -264 c Blackwell Publishing, 2005.This article describes couples attending family counselling in Sweden. The study group is compared with clinical groups and non-clinical groups. Self-rating instruments were com-pleted by 317 women and 312 men to evaluate the following: marital sa

2017doctoralproject

Project for Doctoral Studies in States of Consciousness (including hypnosis and dissociation) and Parapsychology Project for Doctoral Studies in States of Consciousness and Parapsychology (handledning på svenska eller engelska) As part of programmatic research on states of consciousness and anomalous psychology, my associates and I at the Center for Research on Consciousness and Anomalous Psycholo

https://www.psy.lu.se/en/sites/psy.lu.se.en/files/2017doctoralproject.pdf - 2026-05-08

States of consciousness and parapsychology

Project for Doctoral Studies in States of Consciousness (including hypnosis and dissociation) and Parapsychology Project for Doctoral Studies in States of Consciousness and Parapsychology (handledning på svenska eller engelska) As part of a long-term program of research in states of consciousness and anomalous psychology, my associates and I at the Center for Research on Consciousness and Anomalou

https://www.psy.lu.se/en/sites/psy.lu.se.en/files/states_of_consciousness_and_parapsychology.doc - 2026-05-08

Announcement Effects from Voluntary Partnership Agreements - A Gravity Model Approach

The effects on trade from negotiating and entering voluntary partnership agreement is estimated using forest product trade data from 2000 to 2014 on countries in the Forest Law Enforcement, Governance and Trade (FLEGT) licensing process. Gravity model framework is used and the result shows that beginning negotiations lead to an export drop by approximately 0.6 percent and is relatively stable the

Eosinophil granulocyte interaction with serum-opsonized particles: binding and degranulation are enhanced by tumor necrosis factor alpha

Eosinophils participate in the inflammatory response seen in allergy and helminthic infestation. Their release of granule-bound cationic proteins may play a role in these diseases. Therefore, we investigated mechanisms involved in the release of eosinophil cationic protein (ECP). Serum-opsonized zymosan was phagocytosed by eosinophils, and ECP was released into the phagosomes as judged by immunoel

Analysis of the molecular interplay between Streptococcus pyogenes and its human host

The common human pathogen Streptococcus pyogenes is the causative agent of numerous mild and severe clinical conditions. It expresses a number of secreted or cell wall-anchored proteins that modulate the human immune system and facilitate colonization and spread of the pathogen in the human host. During S. pyogenes infections, human plasma leaks into the site of infection as a consequence of infl

BspK, a serine protease from the predatory bacterium Bdellovibrio bacteriovorus with utility for analysis of therapeutic antibodies

The development of therapeutic and diagnostic antibodies is a rapidly growing field of research, being the fastest expanding group of products on the pharmaceutical market, and appropriate quality controls are crucial for their application. We have identified and characterized the serine protease termed BspK (Bdellovibrio serine protease K) from Bdellovibrio bacteriovorus and here show its activit

Genetic control of collagen-induced arthritis in a cross with NOD and C57Bl/10 mice is dependent on gene regions coding for complement factor 5 and FcγRIIb and is not associated with loci controlling diabetes.

The nonobese diabetic (NOD) mouse spontaneously develops autoimmune-mediated diseases such as diabetes and Sjögren′s syndrome. To investigate whether NOD genes also promote autoimmune-mediatedarthritis we established a NOD strain with an MHC class II fragment containing the Aq class II gene predisposing for collagen induced arthritis (NOD.Q). However, this mouse was resistant to arthritis in contr

New treatments in hemophilia: insights for the clinician.

Hemophilia has evolved from an often fatal hereditary bleeding disorder to a disorder for which safe and effective treatment is available. However, there are several challenges remaining in the treatment of hemophilia. Prophylaxis to prevent bleeding is costly and requires frequent intravenous injections, which are cumbersome for patients. Venous access is often difficult to achieve, especially in

New perspectives on complement mediated immunotherapy

Tumor-specific monoclonal antibodies (mAbs) offer several modes of tumor cell killing, from direct cytotoxic activity to indirect mechanisms employing the host immune system, particularly its innate branch. The latter effector functions seem to dominate among clinically approved anti-cancer mAbs and major efforts are being undertaken by both academia and the pharmaceutical industry with the aim to