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Gemensamma Förvaltningens Verksamhetsplan 2026

FVP 2026.indd Verksamhetsplan 2026 GEMENSAMMA FÖRVALTNINGEN | LUNDS UNIVERSITET GEMENSAMMA FÖRVALTNINGENS VERKSAMHETSPLAN 2026 © Lunds universitet 2026 www.lu.se lu@lu.se TRYCK Media-Tryck, LU Service, Lunds universitet www.mediatryck.lu.se media-tryck@service.lu.se Svanenmärkt trycksak, 341903 PROJEKTLEDARE Susanne Hägerström, Utveckling FORMGIVNING Stefan Andersson, LU Service TEXTBEARBETNING Su

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2026-01/Gemensamma%20f%C3%B6rvaltningens%20verksamhetsplan%202026.pdf - 2026-05-07

Tissue deposits of IgA-binding streptococcal M proteins in IgA nephropathy and Henoch-Schonlein purpura.

IgA nephropathy (IgAN) and Henoch-Schönlein purpura (HSP) are diseases characterized by IgA deposits in the kidney and/or skin. Both may arise after upper respiratory tract infections, but the pathogenic mechanisms governing these diseases remain unclear. Patients with IgAN (n = 16) and HSP (n = 17) were included in this study aimed at examining whether IgA-binding M proteins of group A streptococ

Genetic signature of prostate cancer mouse models resistant to optimized hK2 targeted α-particle therapy

Hu11B6 is a monoclonal antibody that internalizes in cells expressing androgen receptor (AR)-regulated prostate-specific enzyme human kallikrein-related peptidase 2 (hK2; KLK2). In multiple rodent models, Actinium-225-labeled hu11B6-IgG1 ([225Ac]hu11B6-IgG1) has shown promising treatment efficacy. In the present study, we investigated options to enhance and optimize [225Ac]hu11B6 treatment. First,

Activated porcine embryonic brain endothelial cells induce a proliferative human T-lymphocyte response

Transplantation of allogeneic embryonic neural tissue is a potential treatment for patients with Parkinson's and Huntington's diseases. The supply of human donor tissue is limited, and alternatives such as the use of animal (e.g., porcine) donor tissue are currently being evaluated. Before porcine grafts can be used clinically, strategies to prevent neural xenograft rejection must be developed. Kn

Antileukoproteinase - Modulation of neutrophil function and therapeutic effects on anti-type II collagen antibody-induced arthritis

Objective. Antileukoproteinase (ALP) is a physiologic inhibitor of granulocytic serine proteases. The present study was undertaken to investigate its therapeutic benefit in an antibody-transfer model of erosive polyarthritis and to elucidate its potential to interfere with immune complex-dependent inflammatory pathways. Methods. Arthritis development was induced in male (BALB/c x B10.Q)F-1 mice by