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Selective depletion of nerve growth factor receptor-bearing neurons in the basal forebrain cholinergic system nuclei by the immunotoxin 192 IgG-saporin offers a new and highly useful tool for the study of the role of the forebrain cholinergic system in cognitive functions. In the present study, we have tested the effects of 192 IpG-saporin in an operant delayed matching-to-position task which has
Foetal cell transplantation in patients with Parkinson's disease can induce motor complications independent of L-DOPA administration, known as graft-induced dyskinesia. In the 6-OHDA lesioned rat model of Parkinson's disease, post-transplantation abnormal movements can develop in response to an amphetamine challenge, a behaviour which is used to model graft-induced dyskinesia. Although L-DOPA-indu
While leukocyte interferon was found therapeutically ineffective in a series of 20 patients with metastatic malignant melanoma, subsequent combination treatment with interferon and cimetidine induced 5 complete and 1 partial tumour remissions. Prior to interferon therapy initiation, regressor patients demonstrated a significantly greater ability to mediate antibody-dependent cellular cytotoxicity
AIM: A survival benefit has been observed for colorectal cancer patients with peritoneal carcinomatosis treated by cytoreductive surgery with intraoperative hyperthermic intraperitoneal chemotherapy (HIPEC). However, this treatment modality is associated with a considerable morbidity and mortality and in a significant number of patients survival is not improved. We studied whether poor survivors c
BACKGROUND: Malignant pleural mesothelioma (MPM) is a disease mostly confined to the thoracic cavity. Untreated, the median survival is <1 year. Cytoreductive surgery combined with intraoperative hyperthermic intrathoracic chemotherapy is used to kill residual tumor cells on the surface of the thoracic cavity while having limited systemic side effects.METHODS: From August 1998 to August 2001, 22 p
COVID-19 is a major public health threat associated with increased disease burden, mortality, and economic loss to countries and communities. Safe and efficacious COVID-19 vaccines are key in halting and reversing the pandemic. Low confidence in vaccines has been one of the factors leading to hesitancy. We aimed to assess the COVID-19 vaccine confidence (safety and effectiveness), associated facto
Maternal smoking in pregnancy may increase the risk of testicular germ cell cancer (TGCC) in offspring, but current evidence remains inconclusive. We performed a nested case-control study using cotinine measurements in maternal serum and amniotic fluid as a biomarker for tobacco exposure during pregnancy. A total of 654 males with maternal serum (n = 359, ncases/controls = 71/288) and/or amniotic
Streptococcus pneumoniae is a bacterium of great global importance, responsible for more than one million deaths per year. This bacterium is commonly acquired in the first years of life and colonizes the upper respiratory tract asymptomatically by forming biofilms that persist for extended times in the nasopharynx. However, under conditions that alter the bacterial environment, such as viral infec
Mitotic cells attenuate the DNA damage response (DDR) by phosphorylating 53BP1, a critical DDR mediator, to prevent its localization to damaged chromatin. Timely dephosphorylation of 53BP1 is critical for genome integrity, as premature recruitment of 53BP1 to DNA lesions impairs mitotic fidelity. Protein phosphatase 4 (PP4) dephosphorylates 53BP1 in late mitosis to allow its recruitment to DNA les
Insoluble tau aggregates within neurofibrillary tangles are a defining neuropathological feature of Alzheimer's disease (AD) and closely correlate with clinical symptoms. Although tau pathology can be assessed using tau positron emission tomography, a more accessible biomarker is needed for diagnosis, prognosis and tracking treatment effects. Here we present a new plasma tau species, the endogenou
Lund University Centre for Sustainability Studies 2/3 3/3 Klimatförändring som vetenskap och politik, 7,5 högskolepoäng MESS51 LITERATURE LIST 2021-05-20 1/3 Dnr STYR 2021/1324 Science and Politics of Climate Change, 7,5 credits MESS51 litteraturlista fastställd av LUCSUS styrelse den 20 maj 2021. 1. Bathiany, S., Scheffer, M., Van Nes, E., Williamson, M., & Lenton, T. (2018). Abrupt Climate Chang
https://www.lumes.lu.se/sites/lumes.lu.se/files/2021-05/MESS51%20Climate%20Change%20May%202021.docx - 2026-06-23
Human Rights and Gender Equality in Climate and Disaster Displacement Human Rights and Gender Equality in Climate and Disaster Displacement This capacity building programme is designed to contribute directly to the Global Mayors Action Agenda on Climate and Migration. This will be done by strengthening the capacity of municipal authorities in multiple cities in Africa, with a prior- ity focus on F
The hydrophilic nonapeptide Ser-Asp-Ala-Arg-Glu-Asn-Ile-Gln-Arg, identical with residues 59-67 of human amyloid protein A (AA) and serum amyloid protein A (SAA), was covalently bound via its carboxyl-terminal end to the carrier-protein keyhole limpet haemocyanin. The complex was injected subcutaneously into ten rabbits. All rabbits produced antisera which, unabsorbed, were specific for AA and SAA.
62060-Ornis-4-06_PL_64s-4x16-SW-ark 183 ORNIS SVECICA 16: 183–210, 2006 Abstract Introduction Much of the terrestrial habitats of the world have been transformed by human influences. In Swe- den, as elsewhere, farming and forestry have been the most important factors. Only a few percent of the productive land have been more or less unaf- fected in parts of northern and almost nothing in southern S
https://www.luvre.lu.se/sites/luvre.lu.se/files/luvre-1352006svenssonheden38ar.pdf - 2026-06-23
The Malmö Diet and Cancer Study The Malmö Diet and Cancer Study Department of Clinical Sciences Skåne University Hospital, Malmö Lund University The Malmö Diet and Cancer Study The EPIC cohort Vital Status – Cancer Endpoints End of follow-up: 31 December 2016 Report: 16 November 2017 1. Cohort 2. Lost to follow-up 3. Vital status 4. Time of follow-up 5. Cause-of-death 6. Cancer endpoints Anders Da
https://www.malmo-kohorter.lu.se/sites/malmo-kohorter.lu.se/files/mdc_vital_cancer_endpoint_report_2017.pdf - 2026-06-23
Sustainability of Intensive Shrimp Farming: Sustainability of Intensive Shrimp Farming: A Case Study in Ninh Thuan, Vietnam By: Soo Kum Lin, Joyce LUMES Lund University P.O. Box 170 221 00 Lund SWEDEN Mobile:+46 070 698 11 56 Email: joycesoo@hotmail.com Supervisor: Dr. Mats G E Svensson Centre for Environmental Studies, MICLU Lund University P.O. Box 170 221 00 Lund SWEDEN Telephone: +46 0703 89 8
https://www.lumes.lu.se/sites/lumes.lu.se/files/soo_joyce.pdf - 2026-06-23
PowerPoint Presentation Introduction to the research areas biodiversity and ecosystem services Johan Ekroos & Yann Clough Centre for Environmental and Climate Research Genetic diversity Species diversity Ecosystem diversity Biodiversity = biological diversity Biodiversity Genetic diversity Distribution of individuals in time and space Distribution of genetic material in time and space Genetic dive
https://www.cec.lu.se/sites/cec.lu.se/files/johan_ekroos_yann_clogh.pdf - 2026-06-23
FALL 2019 CULTURE, ECONOMY AND ECOLOGY (HEKN11) Schedule and literature NB: This schedule is provisional, as of 22 June 2019. Some activities will be added to the schedule and a few other changes made before final version is distributed. TEACHERS: Ingrid.Altamirano – CPS@keg.lu.se (academic advisor) Ellen Fall (EF) – Ellen.Fall@sambib.lu.se Alf Hornborg (AH) – Alf.Hornborg@hek.lu.se Andreas Malm (
https://www.keg.lu.se/en/sites/keg.lu.se.en/files/hekn11_fall_2019_schedule_provisional.docx - 2026-06-23
