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Background Trials of imatinib have provided evidence of activity in adults with Philadelphia-chromosome-positive acute lymphoblastic leukaemia (ALL), but the drug's role when given with multidrug chemotherapy to children is unknown. This study assesses the safety and efficacy of oral imatinib in association with a Berlin-Frankfurt-Munster intensive chemotherapy regimen and allo geneic stem-cell tr

OBJECTIVE: To study the pharmacodynamics of amoxicillin/clavulanic acid against different strains of Haemophilus influenzae in an in vitro kinetic model. The concentrations used corresponded to human serum levels obtained after 875 mg amoxicillin/clavulanic acid given b.i.d., 500/125 mg amoxicillin/clavulanic acid given t.i.d. and those obtained with a pharmacokinetically enhanced formulation cont

Objectives Biologic agents have dramatically changed treatment of rheumatoid arthritis (RA). To date only scarce head-To-head data exist especially when the biological therapies are given as monotherapy without concomitant disease modifying drugs (DMARDs). Thus the objective of the current study is to evaluate treatment response of all available biological therapies with special focus on utility (

Context. X-ray extragalactic surveys are ideal laboratories for the study of the evolution and clustering of active galactic nuclei (AGN). Usually, a combination of deep and wide surveys is necessary to create a complete picture of the population. Deep X-ray surveys provide the faint population at high redshift, while wide surveys provide the rare bright sources. Nevertheless, very wide area surve

Incretin-based therapy is associated with low risk of hypoglycemia in type 2 diabetes mellitus (T2DM) possibly due to its glucose-dependency in stimulating insulin secretion and a sustained glucagon response during hypoglycemia. This is of special relevance when it is combined with insulin or given to elderly patients since both insulin therapy and high age are associated with impaired glucagon co

Colorectal cancer (CRC) is the third most common cancer worldwide. Increasing evidence suggests that CRC should be considered a heterogeneous disease, with multiple differences between proximal and distal tumours. The immune system may, depending on the context, promote or inhibit tumour growth, and different immune cell subsets have been found to be associated with impaired or improved prognosis

Anesthesiology is the medical specialty dedicated to the relief of pain and care of the surgical patient before, during and after surgery. Most of the work in anesthesiology is routine patient care, but because patients are sick and surgical procedures may develop in unexpected ways, anesthesiology by its nature often involves medical crises. In recent years, two concepts have gained increasing i

Cancer kan drabba vem som helst och kan ha sitt ursprung i många olika områden i kroppen. Antalet nya cancerfall ökar varje år, men vissa typer av cancer har bättre prognos än andra. Den vanligaste cancertypen i Sverige är prostatacancer och den drabbar framför allt äldre män. Prostatacancer har god prognos och det finns effektiva metoder att helt bota prostat- acancer om den behandlas i ett tidigPurpose: Recent developments in external radiotherapy and its utilization with artificial in- telligence (AI) enables advanced treatment plans for a range of different disease sites. By adapting to the anatomy of the day, target coverage can be ensured while sparing more healthy tissue. The purpose of this project was to study the feasibility and benefits of daily cone beam computed tomography (CB

Nowadays, is becoming increasingly frequent holding events in outdoor environments, involving a large number of people, even though these spaces were not designed from a safe prospective, in the way that safety is defined today. In such events, high density conditions is an ongoing issue, as the evacuation becomes very complex, due to the space design and the interaction among the pedestrians. It

This paper investigates to what extent Swedish-English code-switching and recent English loanwords occur in the printed and online versions of five newspapers and magazines. The newspapers and magazines that were included are Aftonbladet, Amelia, Elle, Café, and Helsingborgs Dagblad. The study shows that English was the most common in the printed media, while the hypothesis was that it would be mo

Världen har kommit en bit på vägen mot en grönare framtid, men mer behöver göras för att nå klimatmålen. En viktig del av lösningen är fler förnyelsebara energikällor, såsom solceller. Problemet med solceller i Sverige är dock att solen skiner som mest på sommaren, när elpriserna är låga, och knappt alls på vintern, när elpriserna är höga. Därför hade det varit bra med en lösning som möjliggör attIn order to contribute to reaching the climate goals of the future, power-to-heat (P2H) technologies are a possible solution. A heat pump (HP) or an electric boiler (EB) can be used to produce warm water by utilising cheap electricity from photovoltaic (PV) parks in the summer when there are many hours of sunlight. The warm water can then be stored until winter for use in district heating (DH) whe

Introduction: The demographic changes with population ageing and a rapidly growing share of very old peoplewill put an increasing pressure on the health and social care system. In order to both restrict early retirement and force people to extend their working life reforms are changing pension systems in many European countries. Besides that older people have to extend their working life it is imp

IMPORTANCE The positron emission tomography (PET) tracer [18F]flortaucipir allows in vivo quantification of paired helical filament tau, a core neuropathological feature of Alzheimer disease (AD), but its diagnostic utility is unclear. OBJECTIVE To examine the discriminative accuracy of [18F]flortaucipir for AD vs non-AD neurodegenerative disorders. DESIGN, SETTING, AND PARTICIPANTS In this cross-

Avtagbara täckproteser på implantat – bra lösning för äldre? – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Avtagbara täckproteser på implantat – bra lösning för äldre? 2023-01-16 Foto: iStock/Satjawat Boontanataweepol Äldre personer med försämrad motorik kan ha svårt att göra rent och sk

https://www.vetenskaphalsa.se/avtagbara-tackproteser-pa-implantat-bra-losning-for-aldre/ - 2026-06-02

Barn med cerebral pares vill också ha gympa – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Barn med cerebral pares vill också ha gympa 2011-11-16 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Barn är oerhört kompetenta. De har mycket fantasi och tankar oc

https://www.vetenskaphalsa.se/barn-med-cerebral-pares-vill-ocksa-ha-gympa/ - 2026-06-02

Bäst vård för pengarna – unik studie kartlägger kostnadseffektiviteten vid demensvård – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Bäst vård för pengarna – unik studie kartlägger kostnadseffektiviteten vid demensvård 2017-05-02 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrö

https://www.vetenskaphalsa.se/bast-vard-for-pengarna-unik-studie-kartlagger-kostnadseffektiviteten-vid-demensvard/ - 2026-06-02

Bättre behandling av blåscancer – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Bättre behandling av blåscancer 2013-05-22 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. I år får cirka 2 500 svenskar diagnosen cancer i urinblåsan. Trots att sjukdomen ofta u

https://www.vetenskaphalsa.se/battre-behandling-av-blascancer/ - 2026-06-02

Behandling av grön starr kan påverka näthinnans funktion – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Behandling av grön starr kan påverka näthinnans funktion 2011-11-30 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Det läkemedel som injiceras i ögat fö

https://www.vetenskaphalsa.se/behandling-av-gron-starr-kan-paverka-nathinnans-funktion/ - 2026-06-02