Filtyp
PURPOSE: To characterize the ocular phenotype resulting from mutation of Rab38, a candidate gene for Hermansky-Pudlak syndrome.METHODS: Chocolate mice (cht, Rab38(cht/cht)) and control heterozygous (Rab38(cht/)(+)) and wild-type mice were examined clinically, histologically, ultrastructurally, and electrophysiologically. Mice homozygous for both the Rab38(cht) and the Tyrp1(b) alleles were similar
Context:There is little information on the potential impact of serum 1,25-dihydroxyvitamin D [1,25(OH)(2)D] on bone health including turnover.Objective:The objective of the study was to determine the influence of 1,25(OH)(2)D and 25-hydroxyvitamin D [25(OH)D] on bone health in middle-aged and older European men.Design, Setting, and Participants:Men aged 40-79 years were recruited from population r
Popular Abstract in Swedish Leukemi, "det vita blodet", var ursprungligen en beskrivande diagnos på tillstånd där leukocyter (vita blodkroppar), eller snarare deras maligna, d.v.s. canceromvandlade former, tillväxte i sådan grad att de trängde undan andra blodbildande celler. I en sådan situation drabbas patienterna av blodbrist, infektioner och blödningar. Med tiden har vi lärt oss särskilja olikIn the present thesis, clinicogenetic correlations are investigated in a large population-based series of acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), acute lymphoblastic leukemia, and chronic myeloid leukemia, for which the karyotypes were analyzed at the same center. The karyotypic pattern, i.e. normal karyotype or 1, 2 or ³3 anomalies, does not differ between males and female
The presence of HLA haplotype DR3-DQ2 or DR4-DQ8 is associated with an increased risk of celiac disease. In addition, nearly all children with celiac disease have serum antibodies against tissue transglutaminase (tTG).
Popular Abstract in Swedish Åderförfettning (även kallat åderförkalkning eller ateroskleros) börjar genom att det ?onda kolesterolet? LDL fastnar i väggen på ett blodkärl. Där kan LDL börja modifieras och orsaka inflammation. Inflammationen påskyndas av att vita blodceller kommer in i artärväggen och försöker ta bort fettet. Om en stor mängd fett lagras in, kan det inte avlägsnas. Tillsammans med Atherosclerosis is a chronic inflammatory disease, characterized by the accumulation of lipids and fibrous tissue in the wall of medium and large-sized arteries. The characteristic culprit of the disease is the atheroma, or atherosclerotic plaque, a patchy thickening of the arterial wall which affects the lumen, inducing various degrees of stenosis. The rupture of the atherosclerotic plaques, foll
Relativistic projectile fragmentation of Pb-208 has been used to produce isomers in neutron-rich, A approximate to 190 nuclides. A forward-focusing spectrometer provided ion-by-ion mass and charge identification. The detection of gamma-rays emitted by stopped ions has led to the assignment of isomers in Ta-188, W-190, Re-192, Re-193, Os-195, Ir-197, Ir-198, Pt-200, Pt-201, Pt-202 and Au-203, with
The ATLAS Transition Radiation Tracker (TRT) performance depends critically on the choice of the active gas and on its properties. The most important operational aspects, which have led to the final choice of the active gas for the operation of the TRT at the LHC design luminosity, are presented. The TRT performance expected at these conditions is reviewed, including pile-up effects at high lumino
Popular Abstract in Swedish Vid diabetes råder en oförmåga att hålla nere blodsockret, i synnerhet efter en måltid. Under normala förhållanden orsakar en höjning av blodsockret att insulinfrisättningen stimuleras. Insulin ökar upptaget av glukos i vävnaderna i kroppen, vilket sänker blodsockret. Under vissa förhållanden, såsom fetma, minskar effekten av insulin, ett fenomen som även kallas insulinThe parasympathetic nerves are important for the regulation of insulin secretion, in particular after meal intake. Apart from acetylcholine, several neuropeptides can be found in the parasympathetic nerves innervating the islets of Langerhans, including gastrin-releasing peptide (GRP) and pituitary adenylate cyclase activating polypeptide (PACAP). Exogenous administration of either GRP or PACAP ha
Interactions between host and gut microbial communities are modulated by diets and play pivotal roles in immunological homeostasis and health. We show that exchanging the protein source in a high fat, high sugar, westernized diet from casein to whole-cell lysates of the non-commensal bacterium Methylococcus capsulatus Bath is sufficient to reverse western diet-induced changes in the gut microbiota
Here we describe the parametric response map (PRM), a voxel-wise approach for image analysis and quantification of hemodynamic alterations during treatment for 44 patients with high-grade glioma. Relative cerebral blood volume (rCBV) and flow (rCBF) maps were acquired before treatment and after 1 and 3 weeks of therapy. We compared the standard approach using region-of-interest analysis for change
Abstract in UndeterminedPlans for the European Proteomics Association (EuPA) were conceived and established during 2004 and 2005, and culminated in the formal inception of the Organisation during the 4th HUPO World Congress held in Munich in 2005. The mission from the outset has been three-tiered and is to: i) strengthen the national Proteomics organizations in their efforts; ii) to co-ordinate an
A 10-day-old boy with pulmonary atresia received a right-sided aortopulmonary polytetrafluoroethylene shunt. Three days after the operation he became cyanotic and was reintubated. Shunt occlusion was confirmed with angiography. Recombinant tissue plasminogen activator was given locally into the proximal end of the shunt. The thrombus was completely resolved after 2 days. When administration of rec
A series of phosphorylated test peptides was studied by electron capture dissociation Fourier transform ion cyclotron resonance mass spectrometry (ECD FT-ICR MS). The extensive ECD-induced fragmentation made identification of phosphorylation sites for these peptides straightforward. The site(s) of initial phosphorylation of a synthetic peptide with a sequence identical to that of the phosphorylati
OBJECTIVES: Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease that is challenging to detect at an early stage. Biomarkers are needed that can detect PDAC early in the course of disease when interventions lead to the best outcomes. We highlight study design and statistical considerations that inform pancreatic cancer early detection biomarker evaluation.METHODS: We describe experim
Despite the immense importance of enzyme-substrate reactions, there is a lack of general and unbiased tools for identifying and prioritizing substrate proteins that are modified by the enzyme on the structural level. Here we describe a high-throughput unbiased proteomics method called System-wide Identification and prioritization of Enzyme Substrates by Thermal Analysis (SIESTA). The approach assu
BACKGROUND AND AIMS: Atherosclerosis is a lipid-driven chronic inflammatory disorder of the arteries, and monocytes and macrophages play a central role in this process. Within the atherosclerotic lesion, macrophages can scavenge modified lipids and become the so-called foam cells. We previously reported that the epigenetic enzyme Kdm6b (also known as Jmjd3) controls the pro-fibrotic transcriptiona
MILJÖVETENSKAP Preliminär planering/schema 210621 Kurs: MVEN13 - Miljövetenskap: Analys och metodik, 15 hp HT 2021 Kursansvarig: Nina Reistad NR nina.reistad@fysik.lth.se Lärare: Charlotta Turner CT charlotta.turner@chem.lu.se Anna Lindgren AL anna.lindgren@matstat.lu.se Pål Axel Olsson PAO pal_axel.olsson@biol.lu.se Martijn van Praagh MVP martijn.van_praagh@mv.lu.se Björn Klatt BK bjorn.klatt@bio
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/2021-07/Schema%20MVEN13%20HT21.pdf - 2026-04-29
(enk\344tsvar redovisning j\344mf\366relse GEO och ENES - ny.xls) SVAR JÄMSTÄLLDHETSENKÄT JÄMFÖRELSE MELLAN ENES/GEO 2009 36/53 st anställda från ENES/GEO (varav 12/20 kvinnor och 24/33 män) har svarat på enkäten ALLA SVAR I PROCENT 1. Den praktiska/organisatoriska arbetsmiljön Ja Delvis Nej (Ej svarat) tot ENES 09 Q 67 33 0 0 100 100ENES 09 M 46 54 0 0 100GEO 09 Q 40 55 5 0 100GEO 09 M 42 52 6 0
https://www.geologi.lu.se/sites/geologi.lu.se/files/jolk_enkatsvar_redovisning_jamforelse_geo_och_enes_ac.pdf - 2026-04-29
(enk\344tsvar redovisning j\344mf\366relse GEO och ENES - ny.xls) SVAR JÄMSTÄLLDHETSENKÄT JÄMFÖRELSE MELLAN ENES/GEO 2009 36/53 st anställda från ENES/GEO (varav 12/20 kvinnor och 24/33 män) har svarat på enkäten ALLA SVAR I PROCENT 1. Den praktiska/organisatoriska arbetsmiljön 1a. Har du ett stessigt arbete? Ja Delvis Nej (Ej svarat) tot ENES 09 Q 67 33 0 0 100 ENES 09 M 46 54 0 0 100 GEO 09 Q 40
https://www.geologi.lu.se/sites/geologi.lu.se/files/jolk_enkatsvar_redovisning_jamforelse_geo_och_enes.pdf - 2026-04-29
Verksamhetsplan 2026 EKONOMIHÖGSKOLANS BIBLIOTEK www.ehl.lu.se/biblioteket www.lusem.lu.se/library 1 Verksamhetsplan 2026 – Ekonomihögskolans bibliotek Om biblioteket Ekonomihögskolans bibliotek tillhandahåller informationsresurser för studenter och forskare vid fakulteten. Genom bibliotekets pedagogiska arbete utgör vi en resurs för studenternas lärande kring informationssökning, informationshant
https://www.ehl.lu.se/sites/ehl.lu.se/files/2026-04/Ekonomih%C3%B6gskolans-bibliotek-verksamhetsplan-2026.pdf - 2026-04-29
