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Populärvetenskaplig sammanfattning Det Birimiska eventet i Västafrika – regional och global kontext för bildningen av en bergskedja för 2.35–2.00 miljarder år sedan Den era som kallas Paleoproterozoikum omfattar en tidsperiod för 2500 till 1600 miljoner år sedan. Den tidiga delen av denna period (för cirka 2500–2000 miljoner år sedan) kännetecknas av omvälvande förändringar i geobiosfären. Det aThe crystalline basement of the West African Craton (WAC) was established during the Siderian to Orosirian (circa 2.35-1.95 Ga) Birimian event through accretion of extensive tracts of juvenile crust that was tectonically juxtaposed with Archean cratons. The Birimian crust is comprised of volcanic belts and sedimentary basins that have been intruded by multiple generations of intrusive rocks and ex

Objective: To describe dietary protein intakes and their food sources among 27 redefined centres in 10 countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC). Methods: Between 1995 and 2000, 36 034 persons, aged between 35 and 74 years, were administered a standardized 24-h dietary recall (24-HDR) using a computerized interview software programme (EPIC-S

Popular Abstract in Swedish Dagens storskaliga tillverkning baseras på varor med relativt kort livstid och lågt pris. Vinsterna för tillverkarna kommer från den stora mängden sålda varor. Det finns dock inom många industribranscher krympande vinstmarginaler och många företag söker därför efter nya källor för att uppnå bättre rörelseresultat. Även miljöfrågorna är en utmaning för industrin. VäxandeLife cycle environmental problems have been addressed by a number of strategies. However, the results are mostly lamentable because solutions are searched for within the same paradigms that give rise to the problems. This research questions the vision of linear material growth and searches for ways to sustain economic growth without putting the natural environment under stress. The research explor

Many psychiatric illnesses are associated with early mortality and with an increased risk of developing physical diseases that are more typically seen in the elderly. Moreover, certain psychiatric illnesses may be associated with accelerated cellular aging, evidenced by shortened leukocyte telomere length (LTL), which could underlie this association. Shortened LTL reflects a cell's mitotic history

In this report, methods for risk and vulnerability analysis of technological infrastructure and transport are examined. Fault Tree Analysis, Event Tree Analysis, and QRA can, along with Anticipatory Failure Determination, Hierarchical Holographic Modelling, and System Action Management, be used as methods for risk and vulnerability analysis of technical infrastructure. For risk and vulnerability a

The aim of this project is to make a model which could be used during risk identification in swedish underground stations. The model is based on a risk identification in T-centralen, Stockholm and will in a foreseeable way structure the risk sources that can affect personal safety. There will be suggestions concerning preventive measures in an underground station, both material and organizational.

Popular Abstract in Swedish Bröstcancer är den vanligaste cancerdiagnosen hos svenska kvinnor, ca 8000 tumörer diagnosticeras årligen. Vid rekommendation om behandling till patienter med nyupptäckt bröstcancer utgår man från ett antal prognostiska (risk för återfall och död utan behandling) och prediktiva (risk för återfall och död med specifik behandling) faktorer. Ålder, tumörstorlek, cancercellBreast cancer is a heterogeneous disease with variations in the biological profile and subsequent clinical prognosis. Molecular mechanisms for tumour progression are currently being explored in scientific settings, suggesting parallel evolution of tumour cells at primary and metastatic locations. The molecular profiles could be altered affecting individual patient’s treatment and prognosis. In the

Aim: Kynurenine metabolites are potential modulators of psychiatric disease. We aimed to develop a highly sensitive biochemical analysis of cerebrospinal fluid (CSF) tryptophan (TRP) metabolites, to investigate the stability of metabolites and to confirm our previous findings of aberrant CSF quinolinic acid (QUIN) and picolinic acid (PIC) in suicide attempters using this method. Methodology &

Severe traumatic brain injury (TBI) is associated with high mortality and long-term disability. Inflammation is central to TBI pathophysiology, yet early dynamics of inflammatory mediators in blood and cerebrospinal fluid (CSF) remain incompletely understood, and commonly used assay platforms have rarely been directly compared. We aimed to characterize the inflammatory response in blood and CSF du

The identification of helium nuclei at LHCb is achieved using a method based on measurements of ionisation losses in the silicon sensors and timing measurements in the Outer Tracker drift tubes. The background from photon conversions is reduced using the RICH detectors and an isolation requirement. The method is developed using pp collision data at √s = 13 TeV recorded by the LHCb experiment in th

Background: Systemic low-grade inflammation may be a pathophysiological mechanism in a subtype of depression. In this study we investigate a novel candidate mechanism of inflammatory depression - Selective Glomerular Hypofiltration Syndromes (SGHS) - which are characterized by a reduced estimated glomerular filtration rate (eGFR) based on cystatin C (cysC) relative to eGFR based on creatinine (cre

Background: Environmental enrichment (EE) has been widely reported to improve functional recovery after stroke, yet its effects on chronic inflammation and white matter pathology remain less well defined. The aim of this study was to investigate whether poststroke EE modulates chronic neuroinflammation and white matter pathology and how these changes relate to functional recovery. Methods: Here, w

Carotid sinus massage (CSM) is essential in evaluating recurrent unexplained reflex syncope, as it uniquely identifies cardioinhibitory forms that other tests may miss. CSM is largely underused in clinical practice outside dedicated syncope facilities and, when performed, its execution varies, as does the interpretation of results. Underuse affects the diagnostic yield of CSM in the syncope evalua

White matter (WM) disruption and atrophy is a consequence of traumatic brain injury (TBI) and contributes to persisting cognitive impairment. An increased expression of the myelin-associated axonal outgrowth inhibitor Nogo-A and oligodendrocyte pathology might be negatively associated with postinjury WM changes. Here, we analyzed brain tissue from severe TBI patients, obtained by surgical decompre

Mänsklig aktivitet i buffertzonen på Cypern gör det nödvändigt att för det första utveckla en tydlig förståelse av detta områdes folkrättsliga status och för det andra i möjligaste mån besvara spörsmål om vem som har det folkrättsliga ansvaret där. Före-varande studie behandlar dessa frågor i tre delar: - Kapitel 2 ger en kort beskrivning av buffertzonen och dess historia, från dess inrättande