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The ability of many pathogenic microorganisms to cause infection is dependent on their ability to evade attack by the complement system of the host. One mechanism by which microorganisms may avoid complement attack is to bind complement inhibitory molecules present in the host. This thesis describes studies of the complement inhibitor C4BP and of inter-actions between C4BP and the human pathogen

Emergence of multiple-function products (MFPs) poses a variety of challenges and risks for achieving sustainable consumption and production as well as fair consumer society and universal design. We overviewed MFPs from these viewpoints and then, focusing on product standard as a means to create mechanisms to reduce environmental loads from products, elucidated advantages and limitation of five app

Internationalisation of higher education is a current theme in research and politics of higher education. The theme in this paper is related to present developments and concerns of the growing border-crossing activities that take place between nations and their systems of Higher Education. Higher education is expected to be based on research, research to be an international activity, and the unive

A low-weight aerosol sampler has been developed and tested. Internal losses for both sub-micron and large particles ( < 10 tam) are of the order of 5 %. The size fractionation patterns indicate that the sampler may be used to collect a separate respirable fraction in good agreement with the BMRC standard and a coarse fraction deternuned by the inlet design.

Despite apparently favourable conditions for investment in the bioenergy sector provided by sustained high oil prices and a multitude of policy support measures throughout the EU that are ostensibly intended to create improved economic conditions, many industrialists and investors are still apparently wary of engagement. National policy interventions intended to support and to expand the bioenergy

Historical review of 100 years of relationship between Christians and Muslims in East Africa, with particular reference to challenges of the Christian theological education in relation to Islam.

The individual wishes and priorities of patients with advanced disease are too often neglected, making a deck of cards with statements reflecting potential wishes and priorities a useful conversation tool. However, in the most ill patients, the card selection and sorting process may be too strenuous. The aims of this study were to explore the wishes and priorities of patients receiving palliative

Strupfladder och flämtandning är några av tricken som fåglar tar till för att överleva höga temperaturer. I en allt varmare framtid kanske det inte räcker, skriver fågelforskarna Andreas Nord och Susan J. Cunningham.

BACKGROUND: The frequency of central venous catheter (CVC) related complications in hematological patients has previously been studied but some uncertainty remains. Therefore, this observational cohort study was designed primarily to investigate mechanical and infectious complications related to CVC insertion in hematological patients and secondarily, to identify factors associated with these comp

The food industry stands as one of the most vital manufacturing sectors globally, with an ever-increasing reliance on digitalization and technology-driven processes. However, this advancement comes with an inherent risk of cyberattacks, encompassing data breaches and system disruptions, which can severely impact production and disrupt the entire food supply chain. Consequently, such cyberthreats c

Preeclampsia is a severe pregnancy-related inflammatory disease without an effective treatment. The pathophysiology remains partly unknown. However, an increased inflammatory response and oxidative stress are part of the maternal systemic reaction. Recent data have suggested that dysbiosis of the gut microbiome plays a role in preeclampsia as well as other inflammatory diseases. However, dysbiosis

Rationale: According to the Global Initiative for Obstructive Lung Disease (GOLD), the FEV1/FVC ratio is used to confirm the presence of airflow obstruction in the diagnosis of chronic obstructive pulmonary disease (COPD), whereas FEV1 percent predicted normal value (FEV1%pred) is used for grading its severity. The STaging of Airflow obstruction by the FEV1/FVC Ratio (STAR), and its prediction of

Det är mycket rörelse på AI-fronten nu – både rättsligt, tekniskt och politiskt. Stefan Larsson, jurist och docent i teknik och social förändring vid Lunds universitet, placerar in EU-lagstiftarens AI-förordning i en både global och svensk kontext. Han beskriver processen bakom lagstiftningen, de etiska och principiella grunderna, och hur EU-lagstiftaren hanterar AI-innovationernas explosionsartad