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Platelet count kinetics following Interruption of antiretroviral treatment: Results from the SMART study.

OBJECTIVES: To investigate the mechanisms of platelet kinetics in the SMART study that demonstrated excess mortality with CD4 guided episodic antiretroviral therapy (ART) (drug conservation [DC]) compared to continuous treatment (viral suppression [VS]). Follow up analyses of stored plasma samples demonstrated increased activation of both inflammatory and coagulation pathways after stopping ART.

Peripheral antioxidant markers are associated with total hippocampal and CA3/dentate gyrus volume in MDD and healthy controls-preliminary findings.

Several psychiatric disorders, including major depressive disorder (MDD), are associated with increased blood markers of oxidative stress. The relevance of this to the oxidation-sensitive hippocampus (HC) is unknown. We investigated the relationship between peripheral oxidative stress markers and HC volume in unmedicated individuals with MDD (n=16) and healthy controls (n=19). To conserve power, o

Description of the new I1011 beamline for magnetic measurements using synchrotron radiation at MAX-lab

We report on the characterization of the new I1011 beamline at the MAX-II storage ring, in the MAX-lab synchrotron radiation laboratory and give examples of first results. This beamline is using an Elliptically Polarizing Undulator source, producing soft x-rays of a variable polarization state. It delivers high flux and high brightness circularly polarized x-rays in the energy range 0.2 to 1.7 keV

Linguistic correlates to communicative proficiency levels of the CEFR: The case of syntactic complexity in written L2 English, L3 French and L4 Italian

This study is a contribution to the empirical underpinning of the Common European Framework of Reference for Languages (CEFR), and it aims to identify linguistic correlates to the proficiency levels defined by the CEFR. The study was conducted in a Swedish school setting, focusing on English, French and Italian, and examined the relationship between CEFR levels (A1-C2) assigned by experienced rate

Facilitating Transitions to Sustainable Tourism - The role of the tour operator

Popular Abstract in Swedish Turismindustrin är numera en av världens absolut största industrier. Den är av central betydelse för ekonomisk utveckling och arbetstillfällen i ett stort antal länder. Det finns dock en baksida: turism leder ofta till exploatering av miljön, och bidrar i många fall till sociala och kulturella problem. Dagens turismindustri är inte förenlig med hållbar utveckling och deTourism has become a leading industry in the world and continues to grow rapidly, contributing essentially to economic growth and employment in many countries. Tourism as it looks today poses serious threats to the environment and considerable social and cultural challenges. The problem addressed by this research lies in the weakness of current concepts and practices in pursuit of sustainable tour

Särskolebarn i integrerad skolbarnsomsorg

Popular Abstract in Swedish Huvudtanken i svensk välfärdspolitik är att genom generella åtgärder skapa ett samhälle tillgängligt för alla medborgare. Det är därför viktigt att undvika segregering och särlösningar och i stället höja normalverksamhetens standard. Fritidshemmets mål och uppgifter är desamma för alla barn och kvaliteten i verksamheten ska vara så hög att alla barns behov tillgodoses. The main idea behind the Swedish welfare state is to create a society accessible to all citizens by using to general measures. It is, therefore, important to avoid segregation and special solutions, and instead increase the standard of normal activities. The objectives and tasks of day centres for school-age children are the same for all children and the quality of the operations should be of a st

Examples as Crucial Arguments on 'others'

In this article we take the classic meaning of exemplum as a point of departure to show how examples are marked and used in oral discourse on 'others'. The empirical material is a transcribed focus group interview with Swedish students talking about a trip to Warsaw. Examples may be marked in explicit ways but also in implicit ways. Some examples seem recognizable by their allusive nature, others

Interpersonell kommunikation : en studie av elever med hörselnedsättning i särskolan

Popular Abstract in Swedish Denna studie handlar om interpersonell kommunikation mellan barn och vuxna i särskolan. Specifikt inriktas den på att studera den kommunikation som sker när de kommunikationssätt som parterna använder är teckenspråk och tecken och samtidigt tal. I fokus är elever med hörselnedsättning och utvecklingsstörning, vilken är en liten, unik och outforskad elevgrupp, men också Pupils with impaired hearing and moderate to severe learning difficulties usually go to special schools for the severely learning disabled. Few studies have been conducted on the interpersonal communication among these pupils. The all-embracing aim of this study is to look closer into the communication that takes place during the school day between children and adults, in cases where Sign Language

Urban air pollution disrupts placental microarchitecture and shifts hofbauer cells towards a pro-inflammatory state

Exposure to urban air pollution during early pregnancy is associated with increased risk for adverse pregnancy outcomes, such as preeclampsia (PE), and there is an urgent need to understand how air pollution affects biological mechanisms in the placenta. Hofbauer cells (HBCs) are fetal placental macrophages that regulate immune tolerance in the placenta. They are normally polarized towards an anti

REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells

REST is a transcriptional repressor that targets a group of neuronal genes in non-neuronal cells. In embryonic stem (ES) cells, REST has been implicated in controlling the expression of transcription factor genes that are crucial for lineage determination and for maintaining ES cell potential. Here, we asked whether REST directly regulates neural-specifying genes in mouse ES cells using siRNA-medi

De handikappade och de normala: En studie om social identitet hos elever på riksgymnasium för rörelsehindrade

The aim of this qualitative study was to investigate the social identity of students at upper secondary school for physically disabled students. The youths I drew my attention to suffered from severe physical disabilities and therefore received specially adapted education in small classes, but integrated at an ordinary upper secondary school. By "social identity" I mean how the students

Riskbaserad brandteknisk analys av diskotekslokaler

The purpose of this study is to evaluate the safety of people located in discotheques in case of fire. A quantitative fire riskanalysis (QRA) for three different types of discotheques is carried out. The analysis is based on performance based codes from which fire protection alternatives are analysed. The results of the quantitative fire riskanalysis are described as risk profiles and average risk

From Innovation to Domination: Exercising IPR as abuse of art. 102 TFEU

This thesis deals with the enforcement of intellectual property rights as an abuse of dominance. In particular after refusal to license a patent, which is essential for a standardized technology. Seeking for injunction relief may in some circumstances violate applicable competition law. The analysis will provide a hint, whereas patent holder who is dominating in particular market can or should be

Stridsåtgärder och konkurrerande fackförbund i den svenska modellen - en studie om organisationstvister som mynnar ut i stridsåtgärder

Uppsatsen syftar till att söka förståelse till varför tvister mellan fackförbund om vem som ska teckna kollektivavtal uppstår. Arbetsmarknadernas parter är i allmänhet ense om att det som regel bör finnas ett kollektivavtal på varje avtalsområde. Kollektivavtalets speciella rättsverkningar gör det viktigt för fackförbunden att vara avtalspart i ett kollektivavtal. Kollektivavtalet sätter i stor utThe aim of this essay is to seek understanding about why conflicts appear between trade unions regarding which one of them should sign the collective agreement in the workplace. The labour market parties are in general in an agreement that there should only be one applicable collective agreement in every area of work. The unique effects of the collective agreement make it crucial for the trade uni

Modelling noice exposure from roads : a case study in Burlöv municipality

Ett antal studier har visat att buller har negativa hälsoeffekter (Barregård et al. 2005; Rosvall et al. 2009; Nilsson, Eriksson & Palmqvist 2009). Exempel på problem som kan uppstå på grund av buller är sömnsvårigheter, hjärt- och kärlsjukdomar, minskad inlärning och reducerad kognitiv förmåga (Berglund, Lindvall & Schwela 1999). Dessa typer av hälsoproblem leder till lidande för den enskNoise has negative health effects according to a number of studies (Barregård et al. 2005; Rosvall et al. 2009; Nilsson, Eriksson & Palmqvist 2009). Example of problems that can occur from exposure to noise is sleeping disturbances, heart diseases, lessened learning and reduced cognitive performance (Berglund, Lindvall & Schwela 1999). This kind of problems cause suffering on a personal le

#slutakidnappavårabarn - socialtjänstens hantering av felaktig information. En kvalitativ studie om enheten för barn och unga

The purpose of this study is to examine how social service handles incorrect information about them that is spreading on social media. This study is based on a qualitative method. In order to achieve the purpose of this work, the focus has been on the unit of child protection services and seven social workers have been interviewed. The study shows that social workers only handle incorrect informat