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It is well known that certain cancers have shown clusteringin educational and socioeconomic groups, but recent comprehensive data on clustering by education are limited. We determined standardized incidence ratios (SIRs), adjusted for several variables, for cancer among men and women in six educational groups based on the Swedish Family-Cancer Database. People were identified with a certain educat

Context: Residential care homes (RCHs) are a common place of death. Previous studies have reported a high prevalence of symptoms such as pain and shortness of breath among residents in the last week of life. Objectives: The aim of the study was to explore the presence of symptoms and symptom relief and identify factors associated with symptom relief of pain, nausea, anxiety, and shortness of breat

The present paper reports different applications which have a common data source: Automatic Road Analyzer (ARAN) of the Transport Infrastructure Laboratory of the University of Catania. Data surveyed with ARAN were used to develop performance indicators of the road asset. A BIM model makes possible to improve the flexibility in information access and to merge data with the aim to allow a complete

Sustainably produced renewable biomass has the potential to replace fossil-based feedstocks, for generation of biobased fuels and chemicals of industrial interest, in biorefineries. In this context, seaweeds contain a large fraction of carbohydrates that are a promising source for enzymatic and/or microbial biorefinery conversions. The thermoanaerobe Thermoanaerobacterium AK17 is a versatile ferme

INTRODUCTION: The incidence of pancreatic cancer is around 5 in 100,000, and the 5-year survival is poor. Pancreatic cancer patients have a high disease-specific burden of symptoms, and palliative chemotherapy has varying side effects. The American Society of Clinical Oncology (ASCO) suggests integrating specialized palliative care (SPC) with standard oncological treatment for pancreatic cancer pa

Background Effective cooperation between B-cells and T-cells within the tumor microenvironment may lead to the regression of established tumors. B-cells and T-cells can recognize tumor antigens with exquisite specificity via their receptor complexes. Nevertheless, whether a diverse intratumoral B-cells and T-cell receptor (BCR, TCR) repertoire affects the tumor immune microenvironment (TIME) and c

Meeting stricter legal emission limits and the simultaneous introduction of new synthetic fuels are key challenges for current and future research in the field of engine combustion. A deep knowledge of spray behavior is mandatory to address these problems, as air‐fuel mixture and spray propagation in gasoline direct injection (GDI) are essential processes to achieve a highly efficient and clean co

In an explorative manner, this article uses a data-driven digital history set-up to focus on how the Swedish Riksdag, its political parties and parliament members discussed media issues. By distant reading and topic modeling a dataset of more than 11,000 parliamentary minutes – approximately 400 million characters – the article gives a new perspective of Swedish media history in general and nation

We previously showed that SerpinE2 and the serine protease HtrA1 modulate fibro-blast growth factor (FGF) signaling in germ layer specification and head-to-tail development of Xenopus embryos. Here, we present an extracellular proteolytic mechanism involving this serpin-protease system in the developing neural crest (NC). Knockdown of SerpinE2 by injected antisense morpholino oligonucleotides did

The prevalence of violent conflicts over the last few decades has left numerous countries in the need of thorough rebuilding; from Afghanistan to Cambodia, Sri Lanka, Guatemala, Somalia or Rwanda. In order to assist in the recovery of these post-conflict societies, various peacebuilding strategies and transitional justice mechanisms have been implemented by a range of different actors. However, mo

Bygg- och fastighetsbranschen utgör i dagsläget en betydande andel av Sveriges naturresursutvinning samt klimatpåverkan, där påverkan från traditionella stommar av betong och stål länge har dominerat. Klimatintensiva processer såsom cement- och stålproduktion är bidragande faktorer till att branschen är i behov av en hållbar och cirkulär omställning. Återbruk och cirkulärt byggande erbjuder hållbaToday, the construction and real estate industry accounts for a sizable portion of the market´s material consumption and climate impact, with traditional structural materials such as concrete and steel long dominated. Processes such as cement and steel production contribute to the industry´s need for a sustainable transition and circular transition. Reuse and circular construction offer sustainabl

I denna rapport föreslås en metod som syftar till att fördjupa förståelsen för identifiering av verifieringsbehovet, som rekommenderas i de svenska byggreglerna för analytisk dimensionering av byggnadstekniskt brandskydd. Syftet med denna rapport är att ge vägledning åt ingenjörer att noggrant ta reda på vilken effekt en förändring av en byggnads utformning har på byggnadens brandskyddssystem. FöIn this report a method is proposed that aims to deepen the understanding for identification of the need for verification that is recommended in Swedish regulations for performance based design of fire safety in buildings. The purpose of this report is to provide guidance to engineers on how to thoroughly identify the effect that an alteration to a building design has on the buildings total fire s

På senare år har det diskuterats frenetiskt om arbetet mot gängkriminaliteten. Inom ramen för regeringens 34-punktsprogram, ett program bestående av flera förslag till åtgärder mot gängkriminaliteten i Sverige, infördes en ny tillfällig lag som gäller under en femårsperiod. I april 2020 trädde lagen (2020:62) om hemlig dataavläsning i kraft, för att möjliggöra för de brottsbekämpande myndigheternaOver the past years in Sweden, there has been a lot of discussions concerning the struggle on gang-related misconduct. Enclosed in the framework of the Swedish government's 34-point program, moreover an agenda comprising several proposals for measures to combat gang-related criminality, a new temporary legislation was introduced for a period of five years. In April 2020, the Secret Data Interc

The liberty of religion is not easy to define or regulate. It is closely connected to other liberties and rights. Starting from individual liberty, the consequence will be a right to religion or from religion, the right to change religion or confession, and the right to transition from religion to no religion, or from no religion to religion. It is obvious that the state, the religious denominatio

Tasquinimod (a quinoline-3-carboxyamide) is a small molecule immunotherapy with demonstrated effects on the tumor microenvironment (TME) involving immunomodulation, anti-angiogenesis and inhibition of metastasis. A target molecule of tasquinimod is the inflammatory protein S100A9 which has been shown to affect the accumulation and function of suppressive myeloid cell subsets in tumors. Given the m

Background: Depression and suicidal behavior have been linked to increased blood-brain barrier (BBB) permeability. Platelet-derived growth factor receptor beta (PDGFR-β) is widely expressed in pericytes and promotes BBB integrity. Here, we investigated cerebrospinal fluid (CSF) levels of PDGFR-β in suicide attempters and healthy controls and correlated PDGFR-β to depression symptom severity. Metho