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Abstract not available

Combustion modeling based on a multi-step global reaction mechanism [1] is applied to CFD (Computational Fluid Dynamics) analysis of a scaled swirl-stabilized 4th generation premixed DLE (Dry Low Emission) burner for gas turbines. The flexi-fuel burner consists of a MAIN premixed flame, a premixed PILOT flame and a confined RPL (Rich Pilot Lean) flame. Both steady-state RANS (Reynolds Averaged Nav

The Wilms' tumour gene 1 (WT1) protein is highly expressed in most leukaemias. Co-expression of WT1 and the fusion protein AML1-ETO in mice rapidly induces acute myeloid leukaemia (AML). Mechanisms behind expression of WT1, as well as consequences thereof, are still unclear. Here, we report that the fusion protein BCR/ABL1 increases expression of WT1 mRNA and protein via the phosphatidylinositol-3

Abstract not available

Abstract not available

Brain-derived neurotrophic factor (BDNF) and other neurotrophins are believed to play an important role in affective disorders. In this study we investigated plasma-BDNF response during an incremental exercise test in 18 patients suffering from moderate major depressive disorder (MDD) and 18 controls. The patients were not treated with antidepressants or neuroleptics. Possible associations between

Using NMR and Monte Carlo (MC) methods, we investigate the stability and dynamics of superoxide dismutase 1 (SOD1) in homogeneous crowding environments, where either bovine pancreatic trypsin inhibitor (BPTI) or the B1 domain of streptococcal protein G (PGB1) serves as a crowding agent. By NMR, we show that both crowders, and especially BPTI, cause a drastic loss in the overall stability of SOD1 i

Background: Information is scarce on long-term changes in energy intake (EI), dietary energy density (DED), and body composition in adolescents undergoing laparoscopic Roux-en-Y gastric bypass (RYGB). Objectives: To investigate long-term changes in EI, DED, and body composition in adolescents after LRYGB. Setting: University hospitals, multicenter study, Sweden. Methods: Eighty-five adolescents (6

Förevarande uppsats undersöker EU-domstolens praxis avseende värdeöverföringar mellan originaltillverkare av läkemedel och generikaföretag i samband med patentförlikningar (så kallade ‘RPPSs’) för att urskilja under vilka förutsättningar ett sådant förfarande utgör en syftesöverträdelse. Analysen visar att EU-domstolens avgöranden Generics och Lundbeck förtydligar bedömningen av mer okompliceradeThis thesis examines the CJEU’s case law on value transfers between originator and generic undertakings, in the context of patent settlements, to ascertain the criteria for determining when such a practice amounts to a restriction of competition by object. The thesis finds that the CJ’s rulings in Generics and Lundbeck clarifies the treatment of more straightforward RPPSs and follows established

Det råder en global kontinuerlig teknikutveckling som präglar internet med nya innovationer. Många onlinetjänster på internet bedriver sina verksamheter med hjälp av datainsamling av de digitala konsumenterna. Teknikutveckling kräver en insats från både onlinetjänster som behöver vara fortsatt anpassningsbara och digitala konsumenter som behöver begripa vilka konsekvenser utveckling har. Datainsam

The aim of this study is to investigate how staff who work with persons with mental impairment living in supportive housing describe and reflect on the clients´ self-determination and which options and challenges they experience with respect to putting the intent of the Swedish act concerning support and service for people with certain functional impairments (LSS) regarding self-determination into