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PURPOSE: Graft failure in heart transplant recipients is still the leading cumulative cause of death, rejection related injuries likely being an important contributor. In this study we used a genome-wide association approach using whole-genome data from chromosome 6 to analyze genetic associations with survival after heart transplantation. METHODS: The study included recipient samples from patient

It was believed that Cdk2-cyclin E complexes are essential to drive cells through the G1-S phase transition. However, it was discovered recently that the mitotic kinase Cdk1 (Cdc2a) compensates for the loss of Cdk2. In the present study, we tested whether Cdk2 can compensate for the loss of Cdk1. We generated a knockin mouse in which the Cdk2 cDNA was knocked into the Cdk1 locus (Cdk1Cdk2KI). Subs

We argue that there is a need for a more elaborate and sophisticated discussion of if, and then how, the public library fulfils its social role to con- tribute to democracy. Therefore, we have formed the Lund Critical Library Studies group with a shared interest of contributing to a more nuanced and rich discussion about public libraries. This allows us to engage in discussions on how the library

Today, the underlying theoretical and methodological foundations as well as implementations in the field of accessibility are largely based on plans, metrics and heuristics. There is an obvious tension between these norms and those of the overall spirit of the times, which leans heavily towards improvisations, diversity, and ever-changing affordances. The parallel evolution of human computer inter

While educational research (EdR) and the Scholarship of Teaching and Learning (SoTL) are overlapping fields there remains considerable friction between the two. Shulman, (2011, p. 5), recounts a situation when an EdR colleague accused him “of contributing to the bastardization of the field by encouraging faculty members who were never trained to conduct educational or social science research to en

Mouse embryonic stem cell (mESC) lines were derived by crossing heterozygous transgenic (tg) mice expressing green fluorescent protein (GFP) under the control of the rat tyrosine hydroxylase (TH) promoter, with homozygous alpha-synuclein (aSYN) mice expressing human mutant SNCAA53T under the control of the mouse Prion promoter (MoPrP), or wildtype (WT) mice. The expression of GFP and human aSYN wa

European Resuscitation Council (ERC) issued updated guidelines for postresuscitation care in 2015. This paper provides updated Swedish recommendations for neurological prognostication of patients remaining unconscious after cardiac arrest (CA). The prognostication should be based on independent methods; clinical and neurophysiological examinations, imaging and biomarkers. It should not be performe

This paper deals with those provisions of the new EU Regulation No. 2015/848 on Insolvency Proceedings (Recast) that create a system of national insolvency registers and establish a decentralized system for the interconnection of such registers by means of the European e-Justice Portal.

This paper describes some research stimulated by a fundamental shift that is occurring in the manufacture and marketing of aero engines for commercial and defence purposes, away from the selling of products to the provision of services. The collaborating aerospace company offers contracts under which it remains responsible for the maintenance of engines which have been purchased by airlines throug

Syftet med rapporten är identifiera och analysera uppfattningar om brott i Bosnien under och efter kriget samt beskriva i vilken mån inblandande parter i en konflikt kan förlåta varandra eller försonas. Den empiriska delen av uppsatsen bygger på observationer i Ljubija, tidningsartiklar från området samt fjorton intervjuer. I analysdelen diskuteras det empiriska materialet med utgångspunkt från DuWhat is percieved as a crime in war time varies depending on the war at issue, the eventual peace, the victors and the victims. This study focuses on the resolution of rules that occured in Ljubija, a town in the north-western part of Bosnia-Herzegovina, during the the war 1992-1995, and how it created new conflicts and group formations that live on after the war. After the war a competition for t

Sjuktalet och arbetslöheten samvarierar, genom att sjukfrånvaron tenderar att öka då arbetslösheten minskar, och vice versa. I uppsatsen diskuteras denna samvariation samt dess rekation till förtidspensionering, och den dolda arbetslösheten.