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Forced expression of the Wilms tumor 1 (WT1) gene inhibits proliferation of human hematopoietic CD34(+) progenitor cells

The Wilms tumor gene (WT1) encodes a zinc-finger containing transcription factor present in primitive hematopoietic progenitor cells. WT1 is also highly expressed in most cases of acute myeloid leukemia. Moreover, WT1 can interfere with induced differentiation of leukemic cell lines. These data suggest a function of WT1 in the maintenance of a primitive phenotype and a role in leukemogenesis by in

Kvinnobilder - helgonnamn

The basis of this paper is a comparative study, on the one hand of the frequency of saints' names among the women in medieval Denmark, and on the other of the occurrence of pictures of female saints in the same region. As to certain names, e g Catherine, Barbara and Anne, there is a correspondence of frequency and time, which suggests a deliberate popularization of the saints in question. Othr cas

SSF of steam-pretreated wheat straw with the addition of saccharified or fermented wheat meal in integrated bioethanol production

Background: Integration of second-generation (2G) bioethanol production with existing first-generation (1G) production may facilitate commercial production of ethanol from cellulosic material. Since 2G hydrolysates have a low sugar concentration and 1G streams often have to be diluted prior to fermentation, mixing of streams is beneficial. Improved ethanol concentrations in the 2G production proce

Health officials' perceptions of and preparedness for the impacts of climate variability on human health in the Somali region of Ethiopia

A proactive strategy to respond effectively to health impacts related to climate variability, particularly within vulnerable populations, is of vital importance. Such a strategy can be attained if health officials have a deep understanding of how climate variability affects human health and if the resources available for the health care sector are sufficient. This study assessed the perceptions an

Novel AAV-Based Rat Model of Forebrain Synucleinopathy Shows Extensive Pathologies and Progressive Loss of Cholinergic Interneurons.

Synucleinopathies, characterized by intracellular aggregation of α-synuclein protein, share a number of features in pathology and disease progression. However, the vulnerable cell population differs significantly between the disorders, despite being caused by the same protein. While the vulnerability of dopamine cells in the substantia nigra to α-synuclein over-expression, and its link to Parkinso

On ASLA

The Swedish Association for Applied Linguistics, ASLA (Association suédoise de linguistique appliquée) was formally founded as an autonomous Swedish affiliate of AILA in 1966. The constituting meeting was held at Lund University on April 12, 1966 during which the first chairperson, Professor Bertil Malmberg, was elected. This means that ASLA will be celebrating its 50th anniversary in 2016. Howeve

Reply to commentaries

In our response, we address four themes arising from the commentaries. First, we discuss the distinction between cognition and metacognition and show how to draw it within our framework. Next, we explain how metacognition differs from social cognition. The underlying mechanisms of metacognitive development are then elucidated in terms of interaction patterns. Finally, we consider measures of metac

Kvinnor - vakna, våga! : En studie kring pedagogen och samhällsvisionären Honorine Hermelin Grønbech

Popular AbstractAvhandlingen är en pedagogikhistorisk kvinnobiografi. Min empiri bygger främst på ett biografiskt material bestående av litteratur av och om Honorine Hermelin Grønbech, samt brev från och till henne, radio- och TV-program jämte material kring skolan, protokoll, föreläsningsanteckningar samt samtal med tidsvittnen. Mot bakgrund av en pedagogy-historical and a women’s historical contThe aim of the dissertation is to analyse, in the light of the history of education and of women, ”biographical sections” of the life and work of the Swedish educationalist Honorine Hermelin Grønbech (1886-1977). The focus is on adult education, and in particular female civic education, which set out to encourage Swedish women to exercise their newly won rights of citizenship (1921). The publicat

Velocity measurement by a vision sensor

Vision sensors are of increasing interest for non-intrusive, remote measurements in industrial as well as consumer products. Their operation is based on intelligent techniques for image understanding, followed by robust quantification of the detected phenomenon. A well-known application area is movement detection and isolation. This paper discusses how movement can be detected and quantified by me

Investigating hardware micro-instruction folding in a Java embedded processor

Bytecode folding is an effective technique for speeding up execution in Java virtual machines. This paper investigates a hardware implementation of the aforementioned technique on BlueJEP, a Java embedded processor. Since BlueJEP is a micro-programmed stack machine, we adopt a micro-instruction oriented approach, folding up to four microinstructions (corresponding to up to four bytecodes, on occas

Konkurrensen om offerrollen i överlevandes berättelser efter kriget i Bosnien

I denna artikel analyseras muntligt gestaltade erfarenheter hos 27 överlevande efter kriget i nordvästra Bosnien under 1990-talet. Syftet är att dels beskriva hur de intervjuade framställer det sociala fenomenet «offerskap», dels analysera diskursiva mönster som medverkar i konstruktionen av kategorin «offer». Aktörernas anspråk på statusen «offer» skapar en konkurrens om offerrollen efter kriget.The aim of this article is to analyse verbally portrayed experiences of 27 survivors of the 1990’s war in northwestern Bosnia. My focus is on describing how the interviewees portray the social phenomenon of «victimhood» and on analysing the discursive patterns that contribute to construction of the category «victim». When, after the war, different actors claim this «victim» status, it sparks a com

Evaluating life: Working with ethical dilemmas in education for sustainable development

Codifications of human rights are widely understood as politically established instruments for evaluating human life. The call for such an apparatus emerges as a response to the age-old problem of social organization, constituting – in extension – a means by which to cope with the overall problem of survival. However, evaluating life is inherently problematic. It is problematic as it presupposes a

Postmodern vitalism: från D'Arcy Thompson till Mandelbrot

Man har gett namnet ”vitalister” till de tänkare som tillskriver den levande materian en särskild status. Den särskilda statusen kräver vissa uppoffringar. Vitalismen är tvungen att erkänna ett orsaksbegrepp som avviker markant från det dominerande mekanistiska modellen i det modernistiska programmet. Den vitala ”kraften” eller ”principen”, agerar genom den organiska vävnaden för att orsaka den rö