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The DEK oncoprotein and its emerging roles in gene regulation.

The DEK oncogene is highly expressed in cells from most human tissues and overexpressed in a large and growing number of cancers. It also fuses with the NUP214 gene to form the DEK-NUP214 fusion gene in a subset of acute myeloid leukemia. Originally characterized as a member of this translocation, DEK has since been implicated in epigenetic and transcriptional regulation but its role in these proc

”Noa har inga fel”: om bristfokus i skolans utvecklingssamtal

It has been suggested that a parent–teacher–student conference should centre on the capacities and good qualities of the student. This article focuses on teacher discourse in situations where the students’ answers (in mathematics tests, written assignments etc.) are either entirely or almost entirely correct. The study shows that, in eight cases out of ten, the comments made reflect a “deficiency

Det ljusa och det mörka rummet. Fotografiets limbo mellan död och frihet

Artikeln uppmärksammar hur fotografiet på grund av sin speciella relation till tiden och rummet är förankrat dels i en livsbevarande praxis och dels i en dödsbringande frysning av tid och rum. Artikeln prövar om den mystik som omgärdar den fotografiska praxisen kan spåras till en sådan "dubbel identitet".

Kvarstående sömnstörning efter utmattningssyndrom godkänd som arbetsskada

Rättsläget när det gäller att få en godkänd arbetsskada efter utmattningssyndrom är synnerligen oklart, och det är snarare regel än undantag att dessa ärenden avslås. Vi beskriver hur ett sådant ärende bedömts av Försäkringskassan och Länsrätten. Ärendet gick inte vidare till Kammarrätten, eftersom försäkringskassan godtog Länsrättens dom. Därmed är inte domen vägledande rent juridiskt, men utslag

Relocating the owl of wisdom : Encyclopaedias in a life-historical perspective

Artikeln undersöker människors förhållningssätt till uppslagsverk och encyklopedier i ett livshistoriskt perspektiv under en period när encyklopedier har genomgått dramatiska förändringar. En frågelista som skickats till fasta så kallade meddelare knutna till Folklivsarkivet i Lund har använts som metod. Svaren har analyserats med hjälp av posthumanistisk teori. Analysen visar de sätt som tryckta Encyclopaedias are artefacts that both define and are defined by the culture in which they are produced and used. Encyclopaedias mirror the time of their creation, at the same time as understanding and use of encyclopaedias is tied to both time and space. From the 19th century until the present day encyclopaedias have changed from exclusive and costly Collections of books kept mainly in libraries

Using multifocal electroretinography hard exudates affect macular function in eyes with diabetic retinopathy

To evaluate the influence of hard exudates on macular function in patients with diabetic retinopathy. METHODS: Thirty seven eyes from 27 diabetic patients, aged 57 +/- 14 years, diabetes duration 12.5 +/- 9 years, not previously treated with photocoagulation, underwent fundus photography, multifocal electroretinography (mfERG) and optical coherence tomography (OCT). Hard exudates were graded from

Transient Control of Combustion Phasing and Lambda in a Six-Cylinder Port-Injected Natural-Gas Engine

Fuel economy and emissions are the two central parameters in heavy duty engines. High exhaust gas recirculation rates combined with turbocharging has been identified as a promising way to increase the maximum load and efficiency of heavy duty spark ignition engines. With stoichiometric conditions, a three way catalyst can be used, which keeps the regulated emissions at very low levels. The Lambda

Inequality, Institutions, and Change - The Case of Senegal

The chapter studies the relationship between inequality and institutional change in the long-run. The key message is that societies change slowly and unpredictably because of path dependency of economic, political, and social institutions. Prevalent inequalities between different groups rooted in history may help to explain why change does not take place. This has implications for the results that

The Early Church as a Narrative Fellowship. An Exploratory Study of the Performance of the Chreia

The early Church was a narrative fellowship which narrativized the Jesus tradition and per-formed it from memory. It did so by using specific narrative and mnemonic forms of commu-nication. The chreia combines features of narrativity, oral performance, and memory and con-stituted a basic element of the narrative mosaic of the Church. The author of the Gospel of Mark indicates a broader pattern of

Diurnal IOP fluctuation: not an independent risk factor for glaucomatous visual field loss in high-risk ocular hypertension.

Purpose: To establish whether intraocular pressure (IOP) fluctuations contribute to the risk of developing glaucoma in patients with high-risk ocular hypertension. Methods: Ninety patients included in the Malmo Ocular Hypertension Study were examined every 3 months with office-hours diurnal tension curves and computerised perimetry. Patients were followed up prospectively for 10 years or until gla

The Baltic salmon in battle with pollutants and disease. / Östersjölaxen i kamp mot miljögifter och sjukdom.

The Baltic salmon has during the latter part of the 20th century been subjected to several threats. Most notable have been the high levels of contaminant release and a disease that causes early life mortality of the young. Ever since utilization of water power from the Swedish rivers began in the 1940ies, thus deminishing the natural breeding areas for the salmons, an extensive hatchery program ha

Law, Deviation and Paradigmatic Change: Copyright and its Metaphors

Drawing on debates in Sweden about Internet freedom, particularly those connected to copyright and file sharing, and on the European legislative trend of amending copyright, this chapter analyses metaphors and conceptions in terms of a societal paradigmatic shift and the collision of mentalities. Kuhnian paradigms are wedded with the mentalities of the French Annales School of historic research. T

Enabling design

Designed to meet the diverse needs of therapists, this book presents a new approach to rehabilitation that integrates ergonomics concepts to address the wide range of problems commonly encountered by professionals. The first section addresses general concepts such as anthropometry and tissue mechanics. The next section explores whole body biomechanics, demonstrating the ergonomic effects of physio