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The advent of novel agents for multiple myeloma (MM) is cause for a re-examination of the incidence of second primary malignancies (SPMs). We examined the SPM rate in MM patients who were enrolled in the prospective observational CALM (Collaboration to Collect Autologous Transplant outcome in Lymphoma and Myeloma) study. Between 2008 and 2012, 3204 patients with MM underwent a first autologous hem

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Background Previous trials of corticosteroid or antiviral treatments for Bell's palsy have been underpowered or have had insufficient follow-up. The aim of this study was to compare the short-term and long-term effects of prednisolone and valaciclovir in the recovery of the affected facial nerve in a large number of patients. Methods In this randomised, double-blind, placebo-controlled, multicentr

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Aims: Utilization of cheap and readily available agricultural residues as cheap carbon sources for poly(3-hydroxybutyrate) (PHB) production by Halomonas boliviensis. Methods and results: Wheat bran was hydrolysed by a crude enzyme preparation from Aspergillus oryzae NM1 to provide a mixture of reducing sugars composed mainly of glucose, mannose, xylose and arabinose. Growth of H. boliviensis using

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This statement provides a concise list of diagnostic terms for ECG interpretation that can be shared by students, teachers, and readers of electrocardiography. This effort was motivated by the existence of multiple automated diagnostic code sets containing imprecise and overlapping terms. An intended outcome of this statement list is greater uniformity of ECG diagnosis and a resultant improvement

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At the University Hospital of Malmo, Sweden, standardized trauma charts were used for registration of all jaw fractures from 1972 to 1976. During the year 2005 the aim was to interview all patients treated non-surgically for unilateral mandibular condylar fractures during this period. In total, 49 patients with unilateral condylar fractures were treated non-surgically in 1972-1976. Of these, 23 pa

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Savanner är ett landskap med både träd och gräs som skapar en miljö som varken är skog eller gräsmark. Savanner tar upp cirka en sjättedel av världens totala landyta och de har på grund av detta en stor betydelse för den globala kolbalansen. De flesta savanner har två distinkta säsonger, en regnperiod då vegetationen grönskar samt en period med torka utan nederbörd. Detta gör att förändringar i deSavannahs are land areas where grass and trees co-exists to create a landscape that is neither a grassland nor a forest. It is estimated that savannahs cover approximately one sixth of the global land surface. They also play an important role in the global carbon cycle due to their total size. Most savannahs are characterized with two distinct seasons, one dry season and one wet season where a maj

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Conventional wastewater treatment plants are designed for treating manmade wastewater (e.g., from households and industries) and to protect the environment (e.g., receiving water bodies) and humans from adverse effects.The objective of this work was to investigate the feasibility of treating municipal wastewater without a biological treatment step by applying different separation processes, such a

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This dissertation deals with the effects of nuclear structure on the α-decay properties, and on the fission-yielddistributions from the decay of heavy nuclei. The nuclear-structure and decay properties of superheavynuclei is one of the central topics for investigation. α decay is treated in a microscopic approach employingSkyrme-Hartree-Fock-Bogoliubov wave functions to describe the formation of a

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OBJECTIVES: The aim of this study was to investigate whether there is an association between socioeconomic status, occupation and hospitalization for Parkinson's disease (PD).METHODS: A nationwide database was constructed by linking the Swedish Census to the Hospital Discharge Register to obtain data on all first adult hospitalizations for PD diagnosed in Sweden during the study period from 1987 t

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Background: The mechanically expandable Lotus Valve System is a fully repositionable and retrievable valve with an adaptive seal to minimize paravalvular leak (PVL). The aim of this study was to evaluate the short- and long-term safety and efficacy of the new device with focus on a new implantation technique to reduce the need for a permane

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Objective: To evaluate if perceived barriers to accessing mental healthcare (MHC) among individuals with symptoms of depression are associated with their socio-economic position (SEP). Design: Cross-sectional questionnaire-based population survey from the Lolland-Falster Health Study (LOFUS) 2016-17 of 5076 participants. Participants: The study included 372 individuals, with positive scores for de

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Large multiobject spectroscopic surveys require automated algorithms to optimize their observing strategy. One of the most ambitious upcoming spectroscopic surveys is the 4MOST survey. The 4MOST survey facility is a fibre-fed spectroscopic instrument on the VISTA telescope with a large enough field of view to survey a large fraction of the southern sky within a few years. Several Galactic and extr

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Background: Previous studies suggested that automated peritoneal dialysis (APD) could be improved in terms of shorter treatment times and lower glucose absorption using bimodal treatment regimens, having ‘ultrafiltration (UF) cycles’ using a high glucose concentration and ‘clearance cycles’ using low or no glucose. The purpose of this study is to explore such regimes further using mathematical opt

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In-situ soot characterization has been successfully performed in a 100 kWth down-fired oxy-fuel test furnace using laser-induced incandescence (LII) and extinction measurements. Primarily non-premixed propane flames were investigated in oxy-fuel mode with various concentrations of oxygen in the oxidant. The turbulent flame character was manifested through two-dimensional single-shot LII signals fr

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A decision is the result of comparing one or more alternatives with respect to one or more criteria that we consider relevant to the decision. Decision making can be considered as one of the most important challenges that analysts and experts encounter to solve complex problems. In recent decades, different methods and algorithms have been presented to support decision making. Multi-criteria analy

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People with repeated rapid meal ingestion have been reported to have increased risk of insulin resistance, impaired glucose tolerance and obesity. To explore whether speed of eating a breakfast influences the postprandial rise of glucose, insulin and the incretin hormones, 24 healthy subjects (12 men and 12 women, mean age 62 years) ingested a standardized solid breakfast consisting of 524 kcal (6

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Evacuation times can be shortened in fire scenarios if people choose appropriate routes. Way-finding systems can be used to aid this process, thus their effectiveness needs to be evaluated. In the present study, the way-finding evacuation systems of the Future Circular Collider (FCC) of the European Organization for Nuclear Research (CERN) are investigated as its evacuation design presents several