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For the development of single–ion irradiation system for living cells at the Lund Ion Beam Analysis facility (LIBAF) newly developed pre-cell (PC) detectors have been investigated. Central to the thesis is the fabrication and initial characterization of more than 100 ultra-thin silicon detectors having different thicknesses down to 5 μm with active areas ranging from 0.71 to 0.172 mm2, to be used

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This book chapter discusses and evaluates four different efforts to extend human life: Normalize ageing, Optimize ageing, Retard ageing and postpone death, and Eliminate or overcome ageing and death. I suggest that improved treatment of disease and handicap at all ages should be welcomed. As a secondary effect, this may in many cases result in an extension of individual lives. However, the direct

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Background Overweight, defined by body mass index (BMI), is correlated to complications following pancreaticoduodenectomy (PD). The aim of this study was to evaluate the impact of body constitution, measured with different anthropometric measures, and diabetes on complications following PD. Materials and methods Patients who underwent PD between 2000 and 2015 at Skåne University Hospital were retr

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The contribution of forest harvesting to base cation losses and soil acidification has increased in recent years in Sweden, as the demand for bioenergy has increased and the sulphur deposition has decreased. Thus, new policy tools are required to evaluate the progress of the recovery from acidification, and as a basis for forest management recommendations. In this study we introduce and test a con

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Objective: The primary objective was to evaluate 6-month outcomes for brief and extensive automated telephony interventions targeting problematic alcohol use, in comparison to an assessment-only control group. The secondary objective was to compare levels of problematic alcohol use (hazardous, harmful or probable dependence), gender and age among study participants from clinical psychiatric and ad

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Purpose: Managing focal cartilage injuries in the middle-aged patient poses a challenge. Focal prosthetic inlay resurfacing has been proposed to be a bridge between biologics and conventional joint arthroplasty. Patient selection and accurate implant positioning is crucial to avoid increased contact pressure to the opposite cartilage surface. A customized femoral condyle implant for focal cartilag

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Background: Sweden has closed all institutions and imposed legislation to ensure service and support for individuals with intellectual disability (ID). Understanding mortality among older individuals with ID is essential to inform development of health promotion and disease control strategies. We investigated patterns and risk of mortality among older adults with ID in Sweden. Methods: This retros

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A dose survey of positron emission tomography (PET) examinations was performed in 12 regions of the Russian Federation, where the effective dose values were assessed for the various types of PET examinations. The comparison to similar published data show that the patient doses in Russia are higher than in other countries. Low-dose CT protocols and justification of multiphase CT protocols should be

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Physiological processes of terrestrial plants regulate the land-atmosphere exchange of carbon, water, and energy, yet few studies have explored the acclimation responses of mature boreal conifer trees to climate change. Here we explored the acclimation responses of photosynthesis, respiration, and stomatal conductance to elevated temperature and/or CO2 concentration ([CO2]) in a 3-year field exper

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Background: The aim of this study was to investigate graft preservation, major bleeding, and reinfection rate using negative pressure wound therapy (NPWT) for perivascular surgical site infections (SSIs) in the groin after vascular surgery and factors associated with failure of treatment. Methods: Retrospective data were collected during 2004-2015. Failure of wound treatment was defined as a wound

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Many automated gating algorithms for flow cytometry data are based on the concept of unimodal cell populations. However, in this article, we show that criteria previously used to make decisions on unimodality cannot adequately distinguish unimodal from bimodal densities. We show that dip and bandwidth tests for unimodality, taken from the statistics literature, can do this with consistent and low

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Our goal was to test a cascade model to identify developmental pathways, or chains of risk, from neighborhood deprivation in childhood to alcohol use disorder (AUD) in young adulthood. Using Swedish general population data, we examined whether exposure to neighborhood deprivation during early and middle childhood was associated with indicators of social functioning in adolescence and emerging adul

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Fluorescent molecularly imprinted polymers (MIPs) have received considerable attention for their promising applications in sensing, imaging and diagnostics. Different synthetic methods have been reported to prepare fluorescent MIPs. Here, one-pot polymerization method was developed to synthesize fluorescent MIP nanoparticles (NPs) bearing a suitable fluorescent label as the fluorescence acceptor.

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BACKGROUND: Current guidelines for accessing graphs non-visually are based on giving access to underlying tabular data and reading the values one by one. When data sets are large, it becomes impossible to get an overview.OBJECTIVE: This work presents a proof-of-concept of automated audio description of data sets up to 100 data points that can be used by persons with visual impairment or persons wh

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Importance: Twin studies have assessed sibling resemblance for major depression (MD) but cannot address sources of resemblance across generations. Objective: To clarify the relative importance of genetic and rearing effects on the parent-offspring resemblance for MD. Design: This Swedish population register-based study examined parents and children from the following 5 family types: intact (2 041

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The ATLAS experiment at the CERN Large Hadron Collider has performed searches for new, heavy bosons decaying to WW, WZ and ZZ final states in multiple decay channels using 20.3 fb−1 of pp collision data at s=8 TeV. In the current study, the results of these searches are combined to provide a more stringent test of models predicting heavy resonances with couplings to vector bosons. Direct searches

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In the EUV spectrum of foil-excited 24 MeV Ni ions the decays of the 3 s 3 p3 and 3 s2 3 p 3 d levels to the 3 s2 3 p2 levels of the ground configuration have been observed. For most of the levels decay curves have been obtained. The lifetime results compare well with predictions from semi-empirically scaled HXR calculations. Some problems with cascade repopulations will be discussed.

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Eddy covariance (EC) measurements are often used to validate net ecosystem productivity (NEP) estimated from satellite remote sensing data and biogeochemical models. However, EC measurements represent an integrated flux over their footprint area, which usually differs from respective model grids or remote sensing pixels. Quantifying the uncertainties of scale mismatch associated with gridded flux

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Harmonic periods have wide applicability in industrial real-time systems. Rate monotonic (RM) is able to schedule task sets with harmonic periods up to 100% utilization. Also, if there is no release jitter and execution time variation, RM and EDF generate the same schedule for each instance of a task. As a result, all instances of a task are interfered by the same amount of workload. This property