Filtyp
Background: Epidemiological evidence on weight change and atrial fibrillation (AF) remains limited and inconsistent. Previous studies on body mass index (BMI) in youth and AF rarely considered subsequent BMI. This study aimed to assess the associations of AF with weight change and BMI in youth, as well as modified effect by genetic susceptibility of AF. Methods: The study included 21,761 individua
BACKGROUND: Dual antiplatelet therapy (DAPT) reduces ischemic events but increases bleeding risk, especially in patients with high bleeding risk (HBR). This study aimed to compare outcomes of abbreviated versus standard DAPT strategies in patients with HBR with acute coronary syndrome undergoing percutaneous coronary intervention. METHODS AND RESULTS: Patients from the SWEDEHEART (Swedish Web-syst
Hotspot tracks (quasilinear chains of seamounts, ridges, and other volcanic structures) provide important records of plate motions, as well as mantle geodynamics, magma flux, and mantle source compositions. The Tristan-Gough-Walvis Ridge (TGW) hotspot track, extending from the active volcanic islands of Tristan da Cunha and Gough through a province of guyots and then along Walvis Ridge to the Eten
Background: Alzheimer’s disease (AD) is a common, complex and multifactorial disease that may require screening across multiple routes of referral to enable early detection and subsequent future implementation of tailored interventions. Blood- and eye-based biomarkers show promise as low-cost, scalable and patient-friendly tools for early AD detection given their ability to provide information on
Importance: Identification and preservation of parathyroid glands (PGs) remain challenging despite advances in surgical techniques. Considerable morbidity and even mortality result from hypoparathyroidism caused by devascularization or inadvertent removal of PGs. Emerging imaging technologies hold promise to improve identification and preservation of PGs during thyroid surgery. Observation: This n
BACKGROUND: Autistic people are more likely to report problematic alcohol and other substance use when compared to the general population. Evidence suggests that up to one in three autistic adults may have an alcohol or other substance use disorder (AUD/SUD), although the evidence base for behavioural addictions is less clear. Autistic people may use substances or engage in potentially addictive b
Background: Cleft lip with cleft palate (CLP) is a congenital condition that affects both the oral cavity and the lips. This study estimated the prevalence and mortality of CLP using surveillance data collected from birth defect registries around the world. Methods: Data from 22 population- and hospital-based surveillance programs affiliated with the International Clearinghouse for Birth Defects S
Purpose To determine the potential association between genitourinary (GU) toxicity and planning dose-volume parameters for GU pelvic structures after high-dose intensity modulated radiation therapy in localized prostate cancer patients. Methods and Materials A total of 268 patients who underwent intensity modulated radiation therapy to a prescribed dose of 86.4 Gy in 48 fractions during June 2004-
We propose a novel analytical time-domain model for migration of Raman scattered photons in inhomogeneous two-layer diffusive media. Based on this model, the methods for reconstruction of the Raman spectra of the two layers are developed, tested in simulations and validated on phantom measurements data.
Background: Approximately 40% of cancer patients/survivors develop chronic cancer-related pain (CRP), which is often associated with greater levels of fatigue and cancer worry, all of which are associated with poorer functioning, wellbeing, and greater healthcare costs. Psychological Flexibility (PF) refers to one’s level of openness to and acceptance of physical/emotional experiences and willingn
Soil erosion poses a significant environmental challenge in Dehradun due to its complex, steep terrain, heavy rainfall, and rapid urbanization. This study employed a Google Earth Engine-based approach to assess the average soil loss annually using the Revised Universal Soil Loss Equation (RUSLE). The analysis used various factors, including rainfall-runoff erosivity (R), soil erodibility (K), slop
In this work we introduce the concept of natural ageing via precipitation arising from eutectic cell structure (PEC-ageing). Natural age-strengthening in grey cast iron at room temperature is long recognised yet still poorly understood, despite its beneficial effect on tensile strength and machinability. We investigate its underlying mechanisms by comparing fresh and naturally aged industrial grey
Objective: The European Society for Vascular Surgery (ESVS) has developed clinical practice guidelines for thecare of patients with diseases of the mesenteric and renal arteries and veins, in succession to the first 2017guidelines, with the aim of assisting physicians and patients in selecting the best management strategy.Methods: These guidelines are based on scientific evidence and expert opinio
BACKGROUND: Wolff-Parkinson-White (WPW) syndrome is a rare cardiac disorder that predispose to supraventricular arrhythmias. Prognosis is usually benign, yet there is an increased lifetime risk of sudden death. While typically sporadic, familial clustering has been reported. This study aimed to assess the risk of WPW, arrhythmias, and mortality among siblings of individuals with WPW.METHODS: This
Low-dimensional topological states have transformed our understanding of charge transportation through quantum materials. Many relevant observations have been connected to bismuth (Bi) containing materials or ultrathin Bi films. Here, we studied sub-monolayer amounts of Bi deposition on the In-terminated InSb(111)A surface using various complementary surface science techniques. Bi deposition at el
Investigating metal-semiconductor interfaces is crucial for enabling ultra-thin film growth and tuning the electronic properties. Here we have studied the atomic mechanism of Bi incorporation into the surface of InSb, the III-V semiconductor with the largest spin-orbit coupling, using surface science techniques and theoretical modeling. Bi deposition onto Sb-terminated InSb(111) surfaces at elevat
This paper examines the implications of platforms as a repertoire for knowing and relating the intensities of pandemic restrictions on teaching and schoolwork. Building on platformisation in education, what work platforms do in unpredictable everyday pedagogical encounters is investigated. Specifically, the paper explores a methodological potential with platforms’ capabilities to pull some things
The reliability of a critical industrial component is decided by the durability of the weakest joint or spot. For applications involving high-temperature operational conditions especially coupled with corrosive environments like fuel cell interconnections, molten metal baths, etc., the joints are the most vulnerable regions for catastrophic failure due to localized material degradation by selectiv
Purpose: Positron emission tomography (PET) is increasingly used in neuro-oncology. However, little is known about its application across European institutions and reasons for variable implementation. Methods: Between June and August 2024, members of the European Organisation for Research and Treatment of Cancer - Brain Tumour Group (EORTC-BTG) completed a cross-sectional online survey on PET use
Drawing on archival material from the Danish Guinea Company and central administration, this article discusses the uses of the discourse of the law of nature and nations in the Danish-Dutch war of 1776–1778 on the Guinea Coast and its aftermath. It shows how Danish and Dutch administrators drew on the law of nature and nations to justify their competing claims in the war, which in turn hinged on c
