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INTRODUCTION: Esophageal squamous cell carcinoma (ESCC) carries a poor prognosis, but earlier tumor detection would improve survival. We aimed to develop and externally validate a risk prediction model based on exposure to readily available risk factors to identify high-risk individuals of ESCC.METHODS: Competing risk regression modeling was used to develop a risk prediction model. Individuals' ab

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Women have always played a central role in smallholder agriculture in many farming systems of the Global South. However, they have had, and still have, low access to agricultural information, and even less ability to enact on training or advice received, in comparison to male farmers. The paper investigates what is needed for female smallholders to better benefit from agricultural advice and train

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A crystallogenesis study of human transthyretin using the counter-diffusion method is described as an alternative to conventional convective vapour diffusion and batch approaches for protein crystallization. The X-ray diffraction results show systematic trends that exhibit unique patterns of crystallization and high crystal quality as well as a remarkable degree of coherence within extended crysta

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INTRODUCTION: Behavioral and psychological symptoms of dementia (BPSD) are a common driver of suffering and high care needs. We describe the Swedish BPSD registry, founded in 2010 to develop an evidence base for quality improvement in the care of patients with BPSD. Further, we illustrate the potential of the registry by evaluating how individual BPSD affects mortality. METHODS: The registry provi

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In several circumstances, a level-three automated vehicle cannot continue driving in an automated driving mode and requests a human driver to take over. In this study, a series of experiments to examine how to provide a TOR was conducted. First, for forty-one persons, a HUD icon, earcon, seat vibration, and combinations were compared. The results indicated that the HUD icon-earcon and HUD icon-sea

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Melanin pigments play a critical role in physiological processes and shaping animal behaviour. Fossil melanin is a unique resource for understanding the functional evolution of melanin but the impact of fossilisation on molecular signatures for eumelanin and, especially, phaeomelanin is not fully understood. Here we present a model for the chemical taphonomy of fossil eumelanin and phaeomelanin ba

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The respiratory tract deposited fraction (DF) is the link between exposure and health effects of airborne particles. Here, we investigate how breathing pattern alterations at increasing physical activity affect DF in different regions of the respiratory tract and compare DF between adults and children (5 and 10 years old). We performed a literature review on the alteration of tidal volume with min

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In global cities, the impacts of gentrification on the lives and well-being of socially vulnerable residents have occupied political agendas. Yet to date, research on how gentrification affects a multiplicity of health outcomes has remained scarce. While much of the nascent quantitative research helps to identify associations between gentrification and determined health outcomes, it tends to draw

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Municipal climate resiliency and re-naturing plans are promoting greening and green (re)development, such as the inclusion of new parks, greenways, or rehabilitated shorelines, frequently as a-political, win-win solutions for all residents. Greenwashing and (re)development of green amenities in vulnerable neighborhoods—those often most in need of support toward resilience and adaptation—expose res

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Research on personality traits predicting life outcomes has typically been investigated using the Big Five factors and only occasionally their facets. However, recent research suggests that the use of items (reflecting personality nuances) can account for more predictive variance. The aim of the present study was to examine the predictive validity for various life outcomes comparing the hierarchic

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This article introduces a novel testing system for investigating rock hydromechanical behavior with neutron and X-ray imaging techniques. The system comprises four subsystems: an axial compression system, a confining pressure system, a fluid flow system, and a triaxial cell. In order to enable imaging with both modalities to track fluid flow and deformation in situ and 3D, the cell was designed to

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The Saccharomyces cerevisiae Elongator complex consisting of the six Elp1-Elp6 proteins has been proposed to participate in three distinct cellular processes: transcriptional elongation, polarized exocytosis, and formation of modified wobble uridines in tRNA. Therefore it was important to clarify whether Elongator has three distinct functions or whether it regulates one key process that leads to m

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The first evidence for the Higgs boson decay to a Z boson and a photon is presented, with a statistical significance of 3.4 standard deviations. The result is derived from a combined analysis of the searches performed by the ATLAS and CMS Collaborations with proton-proton collision datasets collected at the CERN Large Hadron Collider (LHC) from 2015 to 2018. These correspond to integrated luminosi

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The main objective of this paper is to develop a readiness index model that can serve as an analytical tool for exploring the achievements of the electrification of transportation systems. We have applied this readiness index model to evaluate the readiness positioning of China, Norway, and Sweden towards transportation electrification. We have chosen these three countries as they represent divers

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Introduction: The Interpersonal-Psychological Theory of Suicide proposes that capability for suicide is acquired through exposure to painful and provocative events (PPEs). Although there is robust evidence for a positive association between aggregate measures of PPEs and risk for suicidal behavior, little is known about the contributions of physical injuries. The present study investigated the rel

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A novel laboratory methodology for analysing hot asphalt fumes from various paving materials is presented and evaluated. This method facilitates comparative assessments, aiming to enhance occupational safety for asphalt workers and ensure safe implementation of new paving materials. Comparative analyses of emissions to air were conducted on standard asphalt and rubber-modified asphalt at different

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Metal cutting technology plays an important role in the automotive and aeronautic sectors, both of whichare important for the Swedish economy. Both make use of traditional grey cast iron and difficult-to-machine materials like titanium alloys and compacted graphite iron. The tools used to machine thesematerials wear at varying rates depending on factors such as contact temperature, pressure, and t

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We present a micro-Raman study of InP/InGaP tandem junction photovoltaic nanowires. These nanowires render possible InGaP compositions that cannot be made in thin films due to strain. The micro-Raman spectra acquired along the nanowires reveal the existence of compositional changes in the InGaP alloy associated with the doping sequence. The heavily Zn-doped InxGa1-xP (x is the In molar fraction) s