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Objective: Acceptance and commitment therapy (ACT) is a transdiagnostic, behavioral treatment focusing on common processes behind different diagnoses. Internet-based treatment programs can improve access to treatment and easily be integrated into the individual’s life. Method: This single-arm, pre-post-follow-up pilot study examined the acceptability, safety, and effectiveness of internet-based AC
Cement manufacturing and utilization is one of the majorly responsible factors for global CO2 emissions. In light of sustainability and climate change concerns, it is essential to find alternative solutions to reduce the carbon footprint of cement. Secondary cementitious materials (SCMs) are helpful in reducing carbon emissions from concrete. One such solution is the use of agricultural waste as S
We present a methodological workflow using two open science tools that we developed. The first, FBAdLibrian, collects images from the Facebook Ad Library. The second, Pykognition, simplifies facial and emotion detection in images using computer vision. We provide a methodological workflow for using these tools and apply them to a case study of the 2020 US primary elections. We find that unique ima
OBJECTIVE: To describe data completeness, targeting and reliability of the Swedish version of the Spinal Cord Independence Measure Self-Report (s-SCIM-SR). DESIGN: Translation and reliability study. SUBJECTS: Programme participants (n = 48) and peer mentors (n = 42) with spinal cord injury enrolled in the INTERnational Project for the Evaluation of "activE Rehabilitation" (inter-PEER). METHODS: Th
Resection of advanced rectal cancer might result in significant tissue loss, including pelvic floor and parts of the vaginal wall. Pelvic floor reconstruction using a musculocutaneous flap offers optimized healing abilities and the possibility of vaginal reconstruction. In Skåne University Hospital, two different flap techniques are used to reconstruct the perineum: the vertical rectus abdominis m
This chapter compares two digital workflows and tool selection for best practice renovation simulation in Portugal and Sweden. Both workflows are part of ongoing research projects that seek to provide a robust workflow adapted to different user needs and scale implementation. While in Portugal, the focus is on the building, the assessment is scaled up to the neighbourhood in Sweden. Geographic inf
Background: Assessing malignancy risk is important to choose appropriate management of ovarian tumors. We compared six algorithms to estimate the probabilities that an ovarian tumor is benign, borderline malignant, stage I primary invasive, stage II-IV primary invasive, or secondary metastatic. Methods: This retrospective cohort study used 5909 patients recruited from 1999 to 2012 for model develo
Background: Addressing attitudes is central to achieving sexual and reproductive health and rights (SRHR) and Agenda 2030. We aimed to develop a comprehensive index to measure attitudinal support for SRHR, expanding opportunities for global trend analyses and tailored interventions. Methods: We designed a new module capturing attitudes towards different dimensions of SRHR, collected via the nation
Background: The absence of Epithelial Membrane Protein 3 (EMP3) on red blood cells (RBCs) underlies the MAM-negative (MAM−) phenotype. EMP3 is a ubiquitous protein found at low levels in most tissues but with higher expression in hematopoietic cells. Low levels of CD44 are a signature of MAM− RBCs due its proposed physical interaction with EMP3, indicating that EMP3 stabilises CD44 in the membrane
BACKGROUND: Recent studies have reported that reduced-dose trimethoprim-sulfamethoxazole (TMP-SMX) may be effective in the treatment of Pneumocystis jirovecii pneumonia (PJP), but data are lacking for patients with hematologic malignancies.METHODS: This retrospective study included all adult hematologic patients with PJP between 2013 and 2017 at 6 Swedish university hospitals. Treatment with 7.5-1
Background/Aim: Anterior resection is the gold standard surgery for high and middle rectal tumors. In cases where anterior resection is not feasible, the surgeon resorts to a non-restorative approach such as Hartmann’s procedure or abdominoperineal resection. It is not well studied how Hartmann’s procedure impacts quality of life. This cross-sectional cohort study compares the long-term quality of
Precision-cut lung slices (PCLS) have gained increasing interest as a model to study lung biology/disease and screening novel therapeutics. In particular, PCLS derived from human tissue can better recapitulate some aspects of lung biology/disease as compared to animal models. Several experimental readouts have been established for use with PCLS, but obtaining high yield and quality RNA for downstr
The demand for better methods for condition control and monitoring of embankment dams will increase in a near future as a result of expected more extreme weather situations. Furthermore the availability demand on hydropower will increase as a result of switching from fossil fuels to wind and solar power, in some countries in combination with decommissioning of nuclear power. Temperature monitoring
Many questions concerning the UPC’s jurisdiction during the transitional period for European Patents under Article 83 UPCA remain unsolved. Focusing on the “opt in” and “opt out” choices under Article 83 (3) & (4), this paper discusses the legal nature and prerequisites of these provisions, as well as the options and strategic choices that patent proprietors and applicants are facing. Consider
Jordan has one of the lowest available water supplies in the world; meanwhile, Jordan has seen a large increase in population and refugee’s fluxes, leading to an increase in water demand. To address this unprecedented water scarcity, Jordan’s water must be used where its social and economic value is highest. Jordan must treat and reuse virtually every drop of water. With using brackish water (i.e,
Symptomatic venous thromboembolism (VTE) occurs in five percent of children treated for acute lymphoblastic leukemia (ALL), but whether a genetic predisposition exists across different ALL treatment regimens has not been well studied. Methods: We undertook a genome-wide association study (GWAS) meta-analysis for VTE in consecutively treated children in the Nordic/Baltic acute lymphoblastic leukemi
The widespread occurrence of lower Eocene chert and porcellanite has been viewed as a major paleoceanographic issue since the advent of ocean drilling, and both biotic and abiotic forcings have been proposed to explain it. We present a reconstruction of indurated siliceous sediment (ISS) and preserved biosiliceous sediment (PBS) occurrences in the Atlantic Ocean through the Paleocene and Eocene (~
Fatigue is one of the principal damage mechanisms in a slender concrete structure under cyclic loads. And needs to be calculated locally through all the structure, considering the lading conditions and the particularities of concrete. The model presented here is capable to account for the fatigue damage in a probabilistic way, relating the annual loading conditions for each point and the degradati
A new target chamber as well as a new 7-axes translation stage with goniometer will shortly be implemented at the LIPSION nanoprobe in Leipzig. This new stage should enable linear motion as well as rotary motion with high precision, positioning accuracy and repeatability. These different features have been investigated online as well as offline, with encouraging results. Along with the new equipme
