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Background: Over the past decade, several PET tracers were developed to visualise and quantify tau pathology in vivo. However, all these tracers have distinct off-target binding, different dynamic ranges and likely different levels of non-specific binding resulting in large variability in semiquantification. We propose to standardise the sampling and the quantification across all available tau tra
For most applications trying to interpret the real world uncertainties will be an important factor to consider, which is also true for Life-Cycle Assessment used for estimating total environmental impact during the life-cycle of products, services, buildings, structures, roads etc. The construction and usage of infrastructure are major causes of emissions and energy use, thus making it even more i
Nature-based tourism in the fragile Arctic environments is emerging as a major environmental concern, mainly due to extreme seasonality in these locations, the lack of suitable infrastructures and planning, and its interference with fragile ecosystems. In Iceland tourism has increased exponentially during the past decades, causing more environmental impacts on the country's natural recourses. Hiki
Previous experiments demonstrated improved outcome following prolonged cerebral ischemia given controlled brain reperfusion using extracorporeal circulation. The current study further investigates this. Young adult pigs were exposed to 30 min of global normothermic cerebral ischemia, achieved through intrathoracic clamping of cerebral arteries, followed by 20 min of isolated mechanical brain reper
Laser-induced fluorescence is a clinical diagnostic tool, used for tumor demarcation and detection. The technique relies on the injection or topical application of a light sensitive drug called a photosensitizer. This substance has the ability to be accumulated to higher concentrations in cancer cells than in normal cells. This accumulation procedure takes from a few hours to several days, dependin
It has recently been established in our group that amphiphilic block copolymers consisting of a hydrophilic and a hydrophobic part can self-assemble in the presence of selective solvents (“water” and “oil”) into a variety of different solution and lyotropic liquid crystalline microstructures. The effects of the “oil” type, hydrophilic block size and hydrophobic block type on the phase behavior and
BACKGROUND: Tumor development requires angiogenesis, and antiangiogenesis has been introduced in the treatment of cancer patients; however, how the cardiovascular phenotype correlates with cancer risk remains ill-defined. Here, we hypothesized that vasoactive peptides previously implicated in angiogenesis regulation predict long-term cancer risk.METHODS: We measured midregional proatrial natriuret
We relate variation in the timing of arrival by migrating birds breeding at northerly latitudes to individual differences in the prior accumulation of energy stores. Balancing starvation risks early in the season against the almost universal declining trend in reproductive prospects with advancing date is seen as an individual decision with fitness consequences. We review three studies implicating
We have performed a comparison of ten models that predict the temporal behavior of laser-induced incandescence (LII) of soot. In this paper we present a summary of the models and comparisons of calculated temperatures, diameters, signals, and energy-balance terms. The models were run assuming laser heating at 532 nm at fluences of 0.05 and 0.70 J/cm(2) with a laser temporal profile provided. Calcu
Ever-increasing global water shortages necessitate more advanced and cost-effective water purification methods. Herein, a novel slow filtration system using natural raw zeolite is proposed as an alternative to traditional quartz sand as a filter medium. The system demonstrates excellent performance in reducing turbidity and removing methylene blue (MB). The natural zeolite-based filtration system
In pursuit of sustainable development within the building industry, there is a shift towards design strategies that are energy efficient and environmentally friendly. The European Commission has a goal of becoming climate-neutral by 2050 and the United Nations has also developed Agenda 2030 to aid in the reduction of the environmental impact. The city of Malmö has also developed a local plan for a
Fully precise static analysis of program behavior is undecidable in theory and infeasible in practice. While individual static analyses can prove specialized invariants about program behavior or resolve narrow ambiguities, real programs are complex composites of many different abstractions and programming patterns. State-of-the-art approaches to program analysis thus generally rely on composite an
Two-dimensional terahertz spectroscopy (2DTS) is a low-frequency analog of two-dimensional optical spectroscopy that is rapidly maturing as a probe of a wide variety of condensed matter systems. However, a persistent problem with 2DTS is the long experimental acquisition times, which prevent its broader adoption. A potential solution, requiring no increase in experimental complexity, is signal rec
The proportionality between crime and punishment is made, and the way it is made makes for a certain kind of criminal law. By analyzing how punitive measures are justified in Swedish criminal law and crime policy through appeals to proportionality, the Article demonstrates how proportionality has been made and remade to legitimize an increasingly punitive crime policy, obscuring the reasons for th
Elastic fibers containing elastin play an important role in tendon functionality, but the knowledge on presence and function of elastin during tendon healing is limited. The aim of this study was to investigate elastin content and distribution in intact and healing Achilles tendons and to understand how elastin influence the viscoelastic properties of tendons. The right Achilles tendon was complet
Electrical impedance tomography (EIT) is a noninvasive imaging modality, where imperceptible currents are applied to the skin and the resulting surface voltages are measured. It has the potential to distinguish between ischaemic and haemorrhagic stroke with a portable and inexpensive device. The image reconstruction relies on an accurate forward model of the experimental setup. Because of the rela
A thorough understanding of the longitudinal phase space (LPS) of the electron beam is of great advantage to any modern linear accelerator (linac), and of critical importance for operating a free electron laser (FEL). While a transverse deflecting structure (TDS) allows full characterization of a beam’s LPS, measurements with a TDS system are often destructive and operationally complex. We present
