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A short-term intervention trial with selenate, selenium-enriched yeast and selenium-enriched milk: effects on oxidative defence regulation

Increased Se intakes have been associated with decreased risk of cancer and CVD. Several mechanisms have been proposed, including antioxidant effects through selenoproteins, induction of carcinogen metabolism and effects on the blood lipid profile. In a 4 x 1 week randomised, double-blind cross-over study, healthy young men supplemented their usual diet with selenate, Se-enriched yeast, Se-enriche

Molecular structure of citric acid cross-linked starch films

The effect of citric acid (CA) on starch films has been examined. A new method to detect cross-linking of starch by CA in solution-cast films by molecular weight measurements is described. Furthermore, we managed to distinguished between free, mono- and di-esterified CA and quantify di-ester content within starch films by using a modification in the method of complexometric titration with copper(I

Methods, quality control and specimen management in an international multicentre investigation of type 1 diabetes: TEDDY

BackgroundThe vast array and quantity of longitudinal samples collected in The Environmental Determinants of Diabetes in the Young study present a series of challenges in terms of quality control procedures and data validity. To address this, pilot studies have been conducted to standardize and enhance both biospecimen collection and sample obtainment in terms of autoantibody collection, stool sam

Effects of heat on meat proteins - Implications on structure and quality of meat products

Globular and fibrous proteins are compared with regard to structural behaviour on heating, where the former expands and the latter contracts. The meat protein composition and structure is briefly described. The behaviour of the different meat proteins on heating is discussed. Most of the sarcoplasmic proteins aggregate between 40 and 60 ° C, but for some of them the coagulation can extend

Effects of low-dose warfarin and aspirin versus no treatment on stroke in a medium-risk patient population with atrial fibrillation.

Objectives. To assess the optimal stroke prevention treatment for patients with atrial fibrillation (AF) and a low-medium risk (<=4%) of stroke. Design. A total of 668 patients with persistent or permanent AF, without an indication for full dose and with adequate rate control on sotalol, were randomized to warfarin 1.25 mg + aspirin 75 mg daily (W/A, 334 patients) or no anticoagulation (C, 334 pa

Connecting Inflammation with Glutamate Agonism in Suicidality

The NMDA-receptor antagonist ketamine has proven efficient in reducing symptoms of suicidality, although the mechanisms explaining this effect have not been detailed in psychiatric patients. Recent evidence points towards a low-grade inflammation in brains of suicide victims. Inflammation leads to production of quinolinic acid (QUIN) and kynurenic acid (KYNA), an agonist and antagonist of the glut

Interventions for preoperative smoking cessation

Background Smokers have a substantially increased risk of postoperative complications. Preoperative smoking intervention may be effective in decreasing this incidence, and surgery may constitute a unique opportunity for smoking cessation interventions. Objectives The objectives of this review are to assess the effect of preoperative smoking intervention on smoking cessation at the time of surgery

Low-Rank Distributed Control with Application to Wind Energy

This thesis addresses three different topics in wind power plant operation. Most of the research is focused on controlling a wind farm that is required to meet a power set-point. In this mode of operation, the wind turbines are able to vary their power production as long as the total power demand is met. The research investigates how this freedom can be used in order to reduce the fatigue loads e

Randomized trial of plasma exchange or high-dosage Methylprednisolone as adjunctive therapy for severe renal vasculitis

Systemic vasculitis associated with autoantibodies to neutrophil cytoplasmic antigens (ANCA) is the most frequent cause of rapidly progressive glomerulonephritis. Renal failure at presentation carries an increased risk for ESRD and death despite immunosuppressive therapy. This study investigated whether the addition of plasma exchange was more effective than intravenous methylprednisolone in the a

Single-Dose Antibiotic Prophylaxis in Core Prostate Biopsy: Impact of Timing and Identification of Risk Factors.

objectives: To assess the level of infectious complications and the impact of timing of a single, prophylactic, oral dose of ciprofloxacin 750 mg given either 2 hours before or in conjunction with ultrasound -guided core biopsy of the prostate in men without recognised risk factors and to analyse potential risk factors. Methods: All men undergoing prostate biopsy for elevated prostate specific ant

Use of 1,10-phenanthroline in estimating metabolically active iron in plants

If calcifuges are forced to grow on a calcareous soil, they usually develop chlorosis. However, total leaf iron (Fe) does not often correlate well with Fe deficiency symptoms. The extraction of 'active' Fe by 1 M HCl or Fe chelators, e.g., 1,10-phenanthroline, may reflect the relation between chlorosis and Fe-concentration in the leaves better than total Fe does. Extraction of 'active' Fe from lea

Relatives' view on collaboration with nurses in acute wards: Development and testing of a new measure

Background: Collaboration between relatives and nurses in acute care settings is sparsely investigated, and that mostly from nurses' point of view. Feasible and valid instruments are needed for assessing collaboration, its prerequisites and outcome. Objectives: To develop and test an instrument to assess, from the relatives' perspective, collaboration between relatives of frail elderly patients an

Interaction Between Renal Function and Microalbuminuria for Cardiovascular Risk in Hypertension The Nordic Diltiazem Study

We investigated whether renal function and microalbuminuria are independent predictors and whether any interaction exists between them, regarding future cardiovascular disease in hypertensive patients (n=10 881) followed for 4.5 years. The primary end points (PEs) were fatal and nonfatal myocardial infarction and stroke and other cardiovascular deaths. Creatinine and glomerular filtration rate (GF

Låt oss prata om psykisk ohälsa - En kvalitativ innehållsanalys av hur psykisk ohälsa framställs i kvällspress utifrån ett stigmaperspektiv

The aim of this study was to achieve an understanding of how public media pictures mental illness with help from a stigma perspective. Throughout the investigation the Stigma Process by Link and Phelan (2001) has been used to understand and interpret the material acquired. In this study 36 articles from the largest Swedish evening papers have been analyzed and the articles have been taken within a

Towards a Green Global Golden Age? : ICT enabled cornucopian sustainability and a suggestion for its reform

This conceptual thesis analyses Carlota Pérez vision of a ‘Green Global Golden Age’ that is supposed to reconcile the tension between economic growth and sustainability (Pérez, 2016b). Aiming to address the pressing issue of continued unsustainability, Pérez’ proposed solution is based on the assumption that technological innovation in the field of Information and Communication Technologies (ICT)

Home ranges and temporal land tenure of Sunda clouded leopards (Neofelis diardi subsp.borneensis) in Indonesian Borneo

Little is known about the spatial ecology of the Sunda clouded leopard (Neofelis diardi). Being rare and elusive rainforest dwellers, studying them is difficult. Basic knowledge on their home ranges and social organization is lacking, yet is crucial for maintaining viable populations in protected areas, in the scope of this Vulnerable species’ conservation. This study uses 10 years’ worth of came

Diabetes mellitus in Adults - Aspects of Incidence, Autoimmunity and C-peptide

Popular Abstract in Swedish Diabetes är en livslång kronisk sjukdom som före upptäckten av insulin 1922 ledde till döden inom 0-5 år från debuten vid ungdomsdiabetes, och inom ca 5-20 år vid åldersdiabetes. Användningen av insulin ändrade detta helt. Istället blev långtidskomplikationer ett hot som förkortade och påverkade livet. Förutom svåra infektioner handlar det om småkärlskomplikationer drabType 1 and type 2 diabetes increase worldwide, leading to a heavy burden of disease and its complications. All 1666 adults aged 18-100 years with new onset diabetes in Kronoberg during 3 years were registered, and type of diabetes classified by pancreatic autoantibodies and C-peptide. Annual incidences of both type 1 and type 2 diabetes were higher than previously described (27.1/100 000 and 378/1

Kustöversvämningar och GIS : en studie om skånska kustnära kommuners arbete samt interpolationsmetodens betydelse av höjddata vid översvämningssimulering

Den globala uppvärmningen orsakar stigande havsnivåer till följd av avsmältning av landis samt termisk expansion av vattnet. Allvarliga konsekvenser befaras till följd av detta, stora landarealer kan komma att svämmas över vilket bland annat kan bidra till klimatflyktingar. Om havsnivån ökar drastiskt står vi i Sverige inför väldiga utmaningar eftersom stora delar av befolkningen är bosatta längs Global warming is causing rising sea levels due to melting of land ice and thermal expansion of water. This could lead to serious consequences around the world, such as environmental refugees. In case of a radical sea level rise, Sweden faces big challenges because many people live along the coasts. This thesis includes a study on how the Scanian coastal municipalities attack the problem of preven

The effect of intravenous ferric carboxymaltose on health-related quality of life in patients with chronic heart failure and iron deficiency: a subanalysis of the FAIR-HF study

Patients with chronic heart failure (CHF) show impaired health-related quality of life (HRQoL), an important target for therapeutic intervention. Impaired iron homeostasis may be one mechanism underlying the poor physical condition of CHF patients. This detailed subanalysis of the previously published FAIR-HF study evaluated baseline HRQoL in iron-deficient patients with CHF and the effect of intr