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A systematic review of radiation therapy trials in several turnout types was performed by The Swedish Council of Technology Assessment in Health Care (SBU). The procedures for evaluation of the scientific literature are described separately (Acta Oncol 2003; 42: 357-365). This synthesis of the literature on radiation therapy for rectal cancer is based on data from 42 randomized trials and 3 meta-a
Popular Abstract in Swedish Äldre människor har ofta många hälsoproblem som t.ex. svårigheter att gå, se, höra, smärta och inkontinens men hur vanligt det är bland de allra äldsta är lite under¬sökt. De olika hälsoproblemen kan finnas samtidigt och i särskilda mönster men få studier har gjorts om detta. När ett hälsoproblem läggs till ett annat kommer det kanske till en punkt när behov av hjälp ärAim: The aim of this thesis was to investigate type, degree and patterns of health complaints, need for help and health-related quality of life across gender among persons aged 75?105 as well as to identify how patterns of health complaints, gender, age and socio-economic factors related to need for help with daily activities and quality of life (Paper I). The aim was also to investigate the preva
Bioethanol has received increasing attention as an alternative to petrol due to the current dependency on supplies from other countries and due to the increased concentration of the greenhouse gas carbon dioxide in the atmosphere. In this thesis, the development of 2nd generation production processes for bioethanol production from the lignocellulosic part of biomass is discussed. The conversion of
We have monitored electrical activity, voltage-gated Ca2+ currents, and exocytosis in single rat glucagon-secreting pancreatic A-cells. The A-cells were electrically excitable and generated spontaneous Na+- and Ca2+-dependent action potentials. Under basal conditions, exocytosis was tightly linked to Ca2+ influx through omega-conotoxin-GVIA-sensitive (N-type) Ca2+ channels. Stimulation of the A-ce
Background: Ideas of patient involvement are related to notions of self-determination and autonomy, which are not always in alignment with complex interactions and communication in clinical practice.Aim: To illuminate and discuss patient involvement in routine clinical care situations in nursing practice from an ethical perspective.Method: A case study based on an anthropological field study amongBackground:Ideas of patient involvement are related to notions of self-determination and autonomy, which are not always in alignment with complex interactions and communication in clinical practice.Aim:To illuminate and discuss patient involvement in routine clinical care situations in nursing practice from an ethical perspective.Method:A case study based on an anthropological field study among pa
Background: Popliteal artery aneurysm (PAA) carries a risk of sudden thromboembolism, resulting in acute limb ischemia (ALI). Since 2010, all 65 year-old-men in Region Skåne are invited for abdominal aortic aneurysm (AAA) screening, and subsequently for PAA if AAA is detected. The aims of the study were to explore if the ratio of PAAs treated electively compared with acute has changed since the im
Planthoppers (Hemiptera: Fulgoromorpha) are a species-rich and globally distributed insect clade with high economic, ecological and evolutionary importance. However, the relationships among planthopper lineages and families remain unclear. Previous efforts based on inconsistent morphological traits, a few genes or limited sampling often resulted in conflicting tree topologies. Here, we used genome
Purpose: To assess implementation of an electronic patient reported outcomes platform, Recovery Tracker, which characterizes short term recovery following radical orchiectomy in patients with testicular cancer. Methods: Recovery Tracker was assigned based on procedure codes to patients undergoing radical orchiectomy at our institution. Patients were surveyed daily for the 10-day postoperative peri
Background: Sonographers have a high risk of musculoskeletal disorders. Sonography involves strenuous postures in the neck and upper limbs, and is visually demanding. Echocardiography is especially challenging, with static postures and monotonous movements. Aim: The overall aim of this thesis was to identify ergonomic risk factors for pain in sonographers, and to propose actions for sustainable wo
Nature-based tourism in the fragile Arctic environments is emerging as a major environmental concern, mainly due to extreme seasonality in these locations, the lack of suitable infrastructures and planning, and its interference with fragile ecosystems. In Iceland tourism has increased exponentially during the past decades, causing more environmental impacts on the country's natural recourses. Hiki
A number of deleterious health effects have been identified from exposure to outdoor airborne particulate matter. Given that in developed countries we spend majority of our time indoors, in private homes about 65 % (Brashe et al., 2005), the understanding of this exposure is important, yet knowledge is sparse. Particle levels indoors are affected by indoor sources, infiltration from outdoors or pa
INTRODUCTION: Several lines of evidence indicate that increased inflammation is associated with Post-Traumatic Stress Disorder (PTSD). We have previously reported that peripheral inflammatory markers are significantly higher in combat-exposed veterans with than without PTSD. This study was designed to replicate these findings in a new study cohort using the same population and recruitment strategi
Background: Over the past decade, several PET tracers were developed to visualise and quantify tau pathology in vivo. However, all these tracers have distinct off-target binding, different dynamic ranges and likely different levels of non-specific binding resulting in large variability in semiquantification. We propose to standardise the sampling and the quantification across all available tau tra
CONTEXT: Pharmacodynamic studies have shown that persistently high platelet reactivity is common in patients with diabetes in spite of clopidogrel treatment. Clinical trials have not convincingly demonstrated that clopidogrel benefits patients with diabetes as much patients without diabetes.OBJECTIVES: To estimate the clinical effectiveness associated with clopidogrel treatment after myocardial in
Restenosis is a major problem after balloon angioplasty and stent implantation. The aim of this study is to introduce gadolinium neutron capture brachytherapy (GdNCB) as a suitable modality for treatment of stenosis. The utility of GdNCB in intravascular brachytherapy (IVBT) of stent stenosis is investigated by using the GEANT4 and MCNP4B Monte Carlo radiation transport codes. To study capture rat
Objective: To estimate the probability of vaginal events (diagnosis and/or surgery) following radical cystectomy (RC) and explore possible risk factors in a nationwide population-based observational registry based study. Patients and Methods: Women undergoing RC for urinary bladder cancer in Sweden, from 1 January 1997 to 31 December 2019, were identified within national registries. Women with any
This study investigates whether incorporating news-based sentiment into the GARCH-MIDAS framework improves volatility forecasts for the OMXS30 in- dex. The sentiment measure is constructed from Swedish business news articles published in Dagens Industri (DI) between 1995 and 2024, using Latent Dirichlet Allocation (LDA) to identify thematic topics and topic-representative articles. The resulting s
Introduction.In policy and political debate, media and information literacy (MIL) is increasingly framed as a civic responsibility and a strategic response to the contemporary ‘information crisis’, marked by disinformation and digital insecurity. This positions MIL as essential to democratic resilience and national security but risks excluding individuals who lack the resources or capacities to meIntroductionIn policy and political debate, media and information literacy (MIL) is increasingly framed as a civic responsibility and a strategic response to the contemporary ‘information crisis’, marked by disinformation and digital insecurity. This positions MIL as essential to democratic resilience and national security but risks excluding individuals who lack the resources or capacities to mee
