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The purpose of this study is to explore the behavior of a dense jet and bottom plume, composed of brine water of heavier effluent into a quiescent homogeneous ambient, discharged into a receiving body of lighter fresh water (tank). This situation is common in connection with freshwater production from sea water (desalination), which produces a brine waste stream, usually discharged back into sea w
Popular Abstract in Swedish Bakgrund Streptococcus pyogenes, eller grupp A streptokocker, är en av de vanligaste sjukdomsframkallande bakterierna hos människan. De orsakar ofta relativt harmlösa och lättbehandlade ytliga infektioner i hals (halsfluss) och hud (svinkoppor) men kan också ge djupare och livshotande infektioner. Dessutom förekommer följdsjukdomar efter infektioner med grupp A streptoPathogenic bacteria often produce potent proteases capable of destroying host tissue thereby providing the bacteria with tools for spreading and nutrient access. This thesis describes how group A, C and G streptococci can acquire surface bound protease activity through an alternative mechanism, namely by binding and activation of the human protease precursor plasminogen. Group A streptococci of c
Based on polymerase chain reaction (PCR) utilizing degenerate primers directed to the second and sixth transmembrane domains of several G-protein-coupled neurotransmitter receptors and screening of a human B-lymphoblast cDNA library, we isolated a cDNA whose predicted amino acid sequence shows considerable homology with human chemoattractant receptors, e.g., 30% overall identity with the C5a anaph
Enzymatic degradation of model cellulose films prepared by a spin-coating technique was investigated by ellipsometry. The cellulose films were prior to degradation characterized by ellipsometry, contact angle measurements, ESCA (electron spectroscopy for chemical analysis) and AFM (atomic force microscopy). At enzyme addition to preformed cellulose films an initial adsorption was observed, which w
Excited-state dynamics and solvent-solute interactions of 1,1'-diethyl-2,2'-cyanine iodine (1122C) in alcoholic solutions are investigated using time-integrated three-pulse photon-echo spectroscopy. 1122C serves as a model compound for ultrafast photoinduced isomerizationa key process in the light reception of plants, bacteria, and human vision. The photoreaction in 1122C is interrogated in depend
When solving elliptic boundary value problems using integral equation methods one may need to evaluate potentials represented by a convolution of discretized layer density sources against a kernel. Standard quadrature accelerated with a fast hierarchical method for potential field evaluation gives accurate results far away from the sources. Close to the sources this is not so. Cancellation an
Alla ryggradsdjur har ett immunförsvar vars funktion är att skydda oss mot mikroorganismer som kan orsaka sjukdom, såsom bakterier och virus. Dessa sjukdomsframkallande ämnen kallas patogener. Immunförsvaret behöver kunna skilja mellan proteiner som kommer från den egna kroppen och från patogener. Molekylerna som kodas av gener i major histocompatibility complex (MHC) har en viktig del i denna ige
The crustal segment Volgo-Uralia is the least known part of the East European Craton. Its crystalline crust is hidden beneath a thick Neoproterozoic to Phanerozoic cover but disclosed by thousands of drill holes. In conjunction with the recent "Tatseis" reflection seismic profile, we conducted the first isotopic study of the Bakaly granitoid block in eastern Volgo-Uralia, which represents a subsur
Före 2005 dömdes gärningspersoner som sexuellt utnyttjat en person som befunnit sig i ett hjälplöst tillstånd för sexuellt utnyttjande enligt 6 kap. 3 § Brottsbalken (BrB). Endast om det var gärningspersonen som själv hade medverkat till offrets hjälplösa tillstånd kunde denne åtalas för våldtäkt. Föranlett av ett stort missnöje och hätsk debatt i media trädde 2005 den nya sexualbrottslagstiftningPrior to 2005, offending persons involved in sexual exploitation of a person who found themselves in a vulnerable situation, were sentenced pursuant to Chapter 6 § 3 The Criminal Code. Only if the offending person had contributed to the victim's vulnerable situation, could he be prosecuted for rape. In 2005, the new sexual offenses law came into force, which was due to a great dissatisfaction
We present a comparison of two-dimensional separation methods and how they affect the degree of coverage of protein expression in complex mixtures. We investigated the relative merits of various protein and peptide separations prior to acidic reversed-phase chromatography directly coupled to an ion trap mass spectrometer. The first dimensions investigated were density gradient organelle fractionat
The spatial distribution of an anti-cancer drug and its intended target within a tumor plays a major role on determining how effective the drug can be at tackling the tumor. This study provides data regarding the lateral distribution of sunitinib, an oral antiangiogenic receptor tyrosine kinase inhibitor using an in vitro animal model as well as an in vitro experimental model that involved deposit
More than six decades ago, Aníbal Pinto Santa Cruz (1959) published his pivotal work, Chile, a case of frustrated development. Almost 65 years later, this concept has been reborn under the massive protests and social unrest of 2019, the COVID pandemic, and the new lithium cycle. Chile, the former “Latin American Miracle,” has become an unstable and troublesome state, not particularly different fro
BACKGROUND: Before this study started, the standard postoperative chemotherapy regimen for stage II-III Wilms' tumour pretreated with chemotherapy was to include doxorubicin. However, avoidance of doxorubicin-related cardiotoxicity effects is important to improve long-term outcomes for childhood cancers that have excellent prognosis. We aimed to assess whether doxorubicin can be omitted safely fro
this paper considers flow around arbitrarily shaped objects. The boundary conditions on the solidboundaries have been applied by replacing the boundary with a surface force distribution on the surface,such that the required boundary conditions are satisfied. The velocity on the boundary is determined byinterpolation or by local (Gaussian space) average. The source terms are determined
Retaining glycoside hydrolases are enzymes that catalyse the breakdown down of glycans through hydrolysis. Due to the double-replacement mechanism of the retaining glycoside hydrolases (GHs), which form an intermediate with part of the glycan covalently attached to the enzyme, some GHs are able to catalyse synthesis reactions called transglycosylation. In transglycosylation reactions a hydroxyl-co
I svenska domstolar utvecklades under en period av över 30 år en påföljds-praxis i narkotikamål som i hög grad avvek från vad som gäller för andra brottstyper. Straffvärdebedömningen inom området styrdes i princip helt och hållet av tabeller grundade på arten och mängden narkotika. En omfattande praxisomläggning ägde rum åren 2011 till 2013. Omläggningen medförde att samtliga relevanta omständigheIn Swedish courts, over a period of more than 30 years, a practice of punishment was developed in drug cases, which largely differed from those of other types of crime. The penal value assessment in the area was basically governed entirely by tables based on the art and amount of drugs. A comprehensive practice review took place between 2011 and 2013. The conclusion was that all relevant circumsta
Sweden is well known for having the world’s most efficient waste management system. Mainstream evaluation of the waste management system generally focuses on economics or psychology perspectives using solely quantitative methods to examine recycling outputs but not waste inputs. However, a rising movement within scholarly literature as well as public discourse points out a need to focus on prevent
Purpose: By studying different sets of data divided by type of economic political context, this thesis investigates if the usage of accounts differs between countries. In more specific, the purpose of this thesis is to investigate if the use of accounts in the CEO letters of Swedish-, UK- and German-based companies differ as a result of having businesses in different political economies. Theoreti
