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Non-small-cell lung cancer (NSCLC) is the leading cause of cancer-related death worldwide, with ~40–50% of patients diagnosed with non-metastatic disease (stages IA–IIIC). The treatment landscape is evolving rapidly as immunotherapies and targeted therapy are introduced in the non-metastatic setting, creating a need to assess patient outcomes prior to their introduction. This real-world study usin
Background: Many patients with psychotic disorders have persistent paranoid ideation and avoid social situations because of suspiciousness and anxiety. We investigated the effects of virtual-reality-based cognitive behavioural therapy (VR-CBT) on paranoid thoughts and social participation. Methods: In this randomised controlled trial at seven Dutch mental health centres, outpatients aged 18–65 yea
The present thesis investigated Swedish nouns differing in concreteness, specificity and emotional content using linguistic, psycholinguistic and neurolinguistic methods. The focus of Paper I was a semantic analysis of discourse produced by a person with a lesion in visual (left occipital) cortex. The results showed that the lesion site was related to with problems processing concrete nouns relateThe present thesis investigated Swedish nouns differing in concreteness, specificity and emotional content using linguistic, psycholinguistic and neurolinguistic methods. The focus of Paper I was a semantic analysis of discourse produced by a person with a lesion in visual (left occipital) cortex. The results showed that the lesion site was related to with problems processing concrete nouns relate
Ageing societies are facing major housing challenges. Understanding and addressing older adults' diverse housing needs and preferences are crucial. Having access to suitable and sustainable housing options can improve social cohesion, independence, health, and well-being. Participatory processes in housing development can enhance inclusion and democratic participation. This study uses Ramlösa Port
Understanding the structure-property relationship in electrocatalysts under working conditions is crucial for the rational design of novel and improved catalytic materials. This paper presents the Aarhus University reactor for electrochemical studies using X-rays (AUREX) operando electrocatalytic flow cell, designed as an easy-To-use versatile setup with a minimal background contribution and a uni
Background: The spread of tau pathology closely correlates with the disease course and cognitive decline in Alzheimer’s disease (AD). Tau-targeting immunotherapies are being developed to stop the spread of tau pathology and thus halt disease progression. In this post hoc analysis of the ADAMANT clinical trial, we examined the performance of AADvac1, an active immunotherapy targeting the microtubul
Background Most women who are high-risk human papilloma virus (hrHPV) positive in a cervical cancer screening test will spontaneously heal from their infection. Visual inspection with acetic acid (VIA) is recommended by the World Health Organization as a triage test for cervical screening, however its accuracy as a triage test has been questioned. In this study, we aimed to examine the sensitivity
Physics classrooms are still clearly marked by practices belonging to a certaineducational past, while teachers are increasingly being asked to teach in lignment with current equality, diversity and inclusion agendas. At the core of this temporal disconnect are teachers’ practices, which are strongly marked by normative regimes in terms of gender, race, ethnicity, class and other social factors. M
Background: Several diagnostic prediction models to help clinicians discriminate between benign and malignant adnexal masses are available. This study is a head-to-head comparison of the performance of the Assessment of Different NEoplasias in the adneXa (ADNEX) model with that of the Risk of Ovarian Malignancy Algorithm (ROMA). Methods: This is a retrospective study based on prospectively include
OBJECTIVES: To explore broadened entry criteria of the 2021 European Resuscitation Council/European Society of Intensive Care Medicine (ERC/ ESICM) algorithm for neuroprognostication including patients with ongoing sedation and Glasgow Coma Scale-Motor score (GCS-M) scores 4–5. DESIGN: Retrospective multicenter observational study. SETTING: Four ICUs, Skane, Sweden. PATIENTS: Postcardiac arrest pa
I argue that Lisa Shapiro’s rational reconstruction of Descartes’s provisional moral code in terms of a broad conception of morality supplies us with an interpretative framework that make historiographical sense of the reception of Descartes’s moral philosophy in an Anglophone context on three occasions: the appeal to Descartes made by Henry More, Henry Sidgwick’s abrupt dismissal, and the ensuing
The majority of approaches for mass appraisal are based on global statistical models that take into account property characteristics, and, in developing countries, location variables are not often explicitly considered. The present study uses Geographic Information Systems (GIS) as an analytical tool to develop a number of location variables and to analyze their impact in the value of properties.
This study aims to evaluate the usability of ecotope maps to predict aquatic ecological consequences of floodplain landscape changes. If successful, this method will be applied to evaluate ecological rehabilitation measures that will be carried out in order to improve the ecological status of the large river plains. Ecological value is reflected in indicator metrics for fish, aquatic vegetation, a
This thesis looks at the issues of land grabbing and climate change in Sub-Saharan Africa. Taking the situations of small-scale farmers – the dominant group of people population-wise and producers of 90 percent of the subcontinent’s food – as its focus, it also looks at how climate change might make land grabbing worse. It is argued that climate change will do so because of: decreased agricultural
Building on previous work on the agenda-shaping powers of the Council Presidency, this heuristic case study identifies and explores a set of important factors that influence the Presidency´s ability to shape the EU-political agenda. The primary material consists of a set of interviews with Portuguese and Commission officials, treating the Portuguese Presidency in 2007. Four main findings are discu
Due to human-induced environmental changes, many natural populations are undergoing extensive fitness declines. Natural or sexual selection could potentially shift the phenotypic mean of critical traits towards new phenotypic optima, promoting evolutionary rescue. However, this process has rarely been studied in natural populations. Furthermore, the population fitness can also be increased by gene
Artificial intelligence (AI) technologies are being widely employed globally to enhance marine safety services and address challenges within the maritime sector. Nevertheless, the provision of these services in East Africa, particularly within the Lake Victoria basin, is deficient and inadequate. Consequently, a study needs to be undertaken to pinpoint certain domains in marine safety that may be
