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Background: Complement C2 deficiency is the most common genetically determined complete complement deficiency and is associated with a number of diseases. Most prominent are the associations with recurrent serious infections in young children and the development of systemic lupus erythematosus (SLE) in adults. The links with these diseases reflect the important role complement C2 plays in both inn
We present a locus-specific protocol suitable for the investigation, from extracted DNA, into natural inter- and intra-specific genetic variation in a group of nine innate immune genes, all belonging to the β-defensin gene family. The products of these genes encode peptides with antimicrobial properties and form part of the innate immune system. The protocol amplifies the exon coding for the pepti
A search is presented for production of dark-matter particles recoiling against a leptonically decaying Z boson in 20.3 fb(-1) of pp collisions at root s = 8 TeV with the ATLAS detector at the Large Hadron Collider. Events with large missing transverse momentum and two oppositely charged electrons or muons consistent with the decay of a Z boson are analyzed. No excess above the Standard Model pred
Research within contingency theory recognizes and postulates the relevance of contextual factors to the design of organizations. Thus organizations are dependent on the environments in which they operate and on the technologies they utilize. Organizations therefore need to process information about their environments and technologies. Information systems, including computerized information sytems,
Activation measures were implemented as a condition for social assistance in Sweden in the 1990s. Generally, the goal has been to promote the transition from welfare to work and to(re)integrate people dependent on social assistance into the labour market. Social assistance is regulated by the Social Services Act, which is a framework law that gives municipalities and individual social workers exte
Abstract: This thesis analyzes the distribution of profits to labor. The factor share distribution has attracted mounting attention from researchers in the last decades, as it has been identified as a central determining factor for economic inequality. However, how the factor share distribution has developed historically is debated. By analyzing the historical wage share for manufacturing workers
A search is presented for direct chargino production based on a disappearing-track signature using 20.3 fb(-1) of proton-proton collisions at root s = 8 TeV collected with the ATLAS experiment at the LHC. In anomaly-mediated supersymmetry breaking (AMSB) models, the lightest chargino is nearly mass degenerate with the lightest neutralino and its lifetime is long enough to be detected in the tracki
The ability of von Willebrand factor (VWF) to bind platelet GP Ib and promote platelet plug formation is measured in vitro using the ristocetin cofactor (VWF:RCo) assay. Automated assay systems make testing more accessible for diagnosis, but do not necessarily improve sensitivity and accuracy.
Osteoporosis is a widespread problem afflicting millions of people. Drynol Cibotinis is a newly developed proprietary botanical combination of eight botanicals including Angelica sinensis, Glycine max, Wild yam, Ligustrum lucidum, Astragalus membranaceus, Cuscuta chinensis, Psoraleae corylifoliae, and Drynaria fortune. Each of the botanicals has been used in traditional Chinese medicine to treat o
Buildings account for 40% of energy use and about one third of CO2 emissions in the EU. The huge energy saving potentials offered by the building sector has been targeted by a large number of policy instruments. To improve policy intervention in this area, more information on the extent to which the applied policy instruments are supporting the development and dissemination of different types of e
Thesis purpose: The purpose of this study is to investigate the interdependencies within the process of partner selection in the fashion and design sector and the emanating criteria for finding the ideal co-branding partner in order to use co-branding as a strategic brand activation tool. Methodology: Multiple Case Study Theoretical perspective: Brand Building and Brand Activation, Relationship Ma
Detta examensarbete behandlar frågan kring vilken påverkan som idrottsarenor har på fastighetsvärden. Studien grundas i de stora arenaprojekt som har genomförts i Sverige under de senaste åren. Bara i Stockholmsområdet har två stora idrottsarenor byggts och en stor idrottsarena rivits. Projekt som dessa är väldigt kapitalkrävande varpå det är viktigt för de inblandade i projekten att ta reda på va
PET waste is the most visible environmental threat in the Maldives, a Small Island Developing State (SIDS). The thesis aims to propose the deposit refund system as a policy intervention, and evaluates the feasibility of introducing the system in the Maldives. In order to see how other SIDS have implemented the policy, the research uses policy evaluation framework to analyse the implementation mech
Under the growing influence of dominant discourses such as ecological modernisation and neo- liberalisation, proposed alternative conservation approaches focus more and more on efficiency. In the realm of biodiversity conservation, synthetic biology - the application of engineering to facilitate and accelerate the design or modification of genetic materials in living organisms – has emerged as an
Many citizens in Ranchi, Jharkhand, suffer from the consequences of contaminated drinking water. The city’s water governance system therefore urgently needs to find ways to bring safe drinking water to its people. Prevalent models in water governance however do not provide effective guidance for the necessary transition process. They lack heuristics that facilitate an in-depth understanding of con
This thesis looks at the issues of land grabbing and climate change in Sub-Saharan Africa. Taking the situations of small-scale farmers – the dominant group of people population-wise and producers of 90 percent of the subcontinent’s food – as its focus, it also looks at how climate change might make land grabbing worse. It is argued that climate change will do so because of: decreased agricultural
Building on previous work on the agenda-shaping powers of the Council Presidency, this heuristic case study identifies and explores a set of important factors that influence the Presidency´s ability to shape the EU-political agenda. The primary material consists of a set of interviews with Portuguese and Commission officials, treating the Portuguese Presidency in 2007. Four main findings are discu
